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Cell-to-cell variability is inherent to numerous biological processes, including cell migration. Quantifying and characterizing the variability of migrating cells is challenging, as it requires monitoring many cells for long time windows…

Biological Physics · Physics 2021-05-06 David B. Brückner , Alexandra Fink , Joachim O. Rädler , Chase P. Broedersz

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

The dynamics of urban systems can be understood from an evolutionary perspective, in some sense extending biological and cultural evolution. Models for systems of cities implementing elementary evolutionary processes remain however to be…

Physics and Society · Physics 2020-05-01 Juste Raimbault

Evolution has fascinated quantitative and physical scientists for decades: how can the random process of mutation, recombination, and duplication of genetic information generate the diversity of life? What determines the rate of evolution?…

Populations and Evolution · Quantitative Biology 2018-04-23 Richard A. Neher , Aleksandra M. Walczak

Computer experiments that mirror the evolutionary dynamics of sexual and asexual organisms as they occur in nature, tested features proposed to explain the evolution of sexual recombination. Results show that this evolution is better…

Populations and Evolution · Quantitative Biology 2018-04-18 Klaus Jaffe

The study of neural computation aims to understand the function of a neural system as an information processing machine. Neural systems are undoubtedly complex, necessitating principled and automated tools to abstract away details to…

Dynamical Systems · Mathematics 2025-07-09 Abel Sagodi , Il Memming Park

For decades, complex networks, such as social networks, biological networks, chemical networks, technological networks, have been used to study the evolution and dynamics of different kinds of complex systems. These complex systems can be…

Social and Information Networks · Computer Science 2020-12-16 Akrati Saxena

We extend the notions of multipole and subsystem symmetries to more general {\it spatially modulated} symmetries. We uncover two instances with exponential and (quasi)-periodic modulations, and provide simple microscopic models in one, two…

Statistical Mechanics · Physics 2021-10-19 Pablo Sala , Julius Lehmann , Tibor Rakovszky , Frank Pollmann

This topic review communicates working experiences regarding interaction of a multiplicity of processes. Our experiences come from climate change modelling, materials science, cell physiology and public health, and macroeconomic modelling.…

General Economics · Economics 2020-02-07 Bernhelm Booss-Bavnbek , Rasmus Kristoffer Pedersen , Ulf Rørbæk Pedersen

We examine the feasibility of predicting and subsequently managing the future evolution of a Complex Adaptive System. Our archetypal system mimics a competitive population of mechanical, biological, informational or human objects. We show…

Disordered Systems and Neural Networks · Physics 2007-05-23 David M. D. Smith , Neil F. Johnson

The paper presents the investigation and implementation of the relationship between diversity and the performance of multiple classifiers on classification accuracy. The study is critical as to build classifiers that are strong and can…

Artificial Intelligence · Computer Science 2008-10-22 R. Musehane , F. Netshiongolwe , F. V. Nelwamondo , L. Masisi , T. Marwala

Isologous diversification theory for cell differentiation is proposed, based on simulations of interacting cells with biochemical networks and cell division process following consumption of some chemicals. According to the simulations of…

adap-org · Physics 2008-02-03 Kunihiko Kaneko , Tetsuya Yomo

Systems evolving according to the standard concept of biological or technological evolution are often described by catalytic evolution equations. We study the structure of these equations and find a deep relationship to classical…

Physics and Society · Physics 2007-05-23 Rudolf Hanel , Stuart A. Kauffman , Stefan Thurner

Many organisms exhibit branching morphologies that twist around each other and become entangled. Entanglement occurs when different objects interlock, creating complex and often irreversible configurations. This physical phenomenon is…

Innovation and evolution are two processes of paramount relevance for social and biological systems. In general, the former allows to introduce elements of novelty, while the latter is responsible for the motion of a system in its phase…

Physics and Society · Physics 2018-04-11 Marco Antonio Amaral , Marco Alberto Javarone

Genetic regulatory networks are usually modeled by systems of coupled differential equations and by finite state models, better known as logical networks, are also used. In this paper we consider a class of models of regulatory networks…

Dynamical Systems · Mathematics 2015-06-26 Ricardo Lima , Edgardo Ugalde

This work concerns a many-body deterministic model that displays life-like properties as emergence, complexity, self-organization, spontaneous compartmentalization, and self-regulation. The model portraits the dynamics of an ensemble of…

Adaptation and Self-Organizing Systems · Physics 2023-07-11 Alessandro Scirè , Valerio Annovazzi-Lodi

Diversity is a fundamental feature of ecosystems, even when the concept of ecosystem is extended to sociology or economics. Diversity can be intended as the count of different items, animals, or, more generally, interactions. There are two…

Physics and Society · Physics 2016-09-14 Andrea Tacchella , Riccardo Di Clemente , Andrea Gabrielli , Luciano Pietronero

We investigate the evolutionary processes behind the development and optimization of multiple threads of execution in digital organisms using the avida platform, a software package that implements Darwinian evolution on populations of…

Biological Physics · Physics 2007-05-23 Charles Ofria , Christoph Adami , Travis C. Collier , Grace K. Hsu

Complex systems' modeling and simulation are powerful ways to investigate a multitude of natural phenomena providing extended knowledge on their structure and behavior. However, enhanced modeling and simulation require integration of…