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Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Alzheimer's disease (AD) is the leading cause of dementia, and its early detection is crucial for effective intervention, yet current diagnostic methods often fall short in sensitivity and specificity. This study aims to detect significant…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Milla E. Nielsen , Mads Nielsen , Mostafa Mehdipour Ghazi

Structural magnetic resonance imaging (sMRI) provides accurate estimates of the brain's structural organization and learning invariant brain representations from sMRI is an enduring issue in neuroscience. Previous deep representation…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Ning Jiang , Gongshu Wang , Tianyi Yan

Cognitive impairments in older adults represent a significant public health concern, necessitating accurate diagnostic and monitoring strategies. In this study, the principal cognitive and neuropsychological evaluations employed for the…

Neurons and Cognition · Quantitative Biology 2024-02-23 Chuang Li , Rubing Lin , Yantong Liu , Yichen Wei

Brain tumors pose a significant threat to human life, therefore it is very much necessary to detect them accurately in the early stages for better diagnosis and treatment. Brain tumors can be detected by the radiologist manually from the…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Sayan Das , Arghadip Biswas

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

Objectives: High classification accuracy of Alzheimer's disease (AD) from structural MRI has been achieved using deep neural networks, yet the specific image features contributing to these decisions remain unclear. In this study, the…

Image and Video Processing · Electrical Eng. & Systems 2025-10-20 Christian Tinauer , Maximilian Sackl , Rudolf Stollberger , Reinhold Schmidt , Stefan Ropele , Christian Langkammer

More than 10.7% of people aged 65 and older are affected by Alzheimer's disease. Early diagnosis and treatment are crucial as most Alzheimer's patients are unaware of having it until the effects become detrimental. AI has been known to use…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Audrey Paleczny , Shubham Parab , Maxwell Zhang

Recent evidence has shown that structural magnetic resonance imaging (MRI) is an effective tool for Alzheimer's disease (AD) prediction and diagnosis. While traditional MRI-based diagnosis uses images acquired at a single time point, a…

Applications · Statistics 2021-11-02 Xiaowu Dai

A brain tumour is a mass or cluster of abnormal cells in the brain, which has the possibility of becoming life-threatening because of its ability to invade neighbouring tissues and also form metastases. An accurate diagnosis is essential…

Image and Video Processing · Electrical Eng. & Systems 2022-01-28 Soumick Chatterjee , Faraz Ahmed Nizamani , Andreas Nürnberger , Oliver Speck

Multiple Sclerosis (MS) is a chronic autoimmune disease of the central nervous system whose molecular mechanisms remain incompletely understood. In this study, we developed an end-to-end machine learning pipeline to analyze transcriptomic…

The application of machine learning algorithms to the diagnosis and analysis of Alzheimer's disease (AD) from multimodal neuroimaging data is a current research hotspot. It remains a formidable challenge to learn brain region information…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Yongcheng Zong , Changhong Jing , Qiankun Zuo

Despite the great promise that machine learning has offered in many fields of medicine, it has also raised concerns about potential biases and poor generalization across genders, age distributions, races and ethnicities, hospitals, and data…

Machine Learning · Computer Science 2023-02-01 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Alzheimer's Disease (AD) is a progressive neurological disorder that can result in significant cognitive impairment and dementia. Accurate and timely diagnosis is essential for effective treatment and management of this disease. In this…

Image and Video Processing · Electrical Eng. & Systems 2024-12-10 Mozhgan Naderi , Maryam Rastgarpour , Amir Reza Takhsha

Despite progress in deep learning for Alzheimer's disease (AD) diagnostics, models trained on structural magnetic resonance imaging (sMRI) often do not perform well when applied to new cohorts due to domain shifts from varying scanners,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-12 Zobia Batool , Diala Lteif , Vijaya B. Kolachalama , Huseyin Ozkan , Erchan Aptoula

This study presents an innovative method for Alzheimer's disease diagnosis using 3D MRI designed to enhance the explainability of model decisions. Our approach adopts a soft attention mechanism, enabling 2D CNNs to extract volumetric…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Gabriele Lozupone , Alessandro Bria , Francesco Fontanella , Frederick J. A. Meijer , Claudio De Stefano

For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining…

Machine Learning · Statistics 2019-03-06 Stefan Konigorski , Shahryar Khorasani , Christoph Lippert

Machine learning algorithms underpin modern diagnostic-aiding software, which has proved valuable in clinical practice, particularly in radiology. However, inaccuracies, mainly due to the limited availability of clinical samples for…

Lung cancer is a very deadly disease worldwide, and its early diagnosis is crucial for increasing patient survival rates. Computed tomography (CT) scans are widely used for lung cancer diagnosis as they can give detailed lung structures.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-04 Md Rashidul Islam , Bakary Gibba , Altagi Abdallah Bakheit Abdelgadir

Identification of brain regions related to the specific neurological disorders are of great importance for biomarker and diagnostic studies. In this paper, we propose an interpretable Graph Convolutional Network (GCN) framework for the…

Machine Learning · Computer Science 2022-04-29 Houliang Zhou , Lifang He , Yu Zhang , Li Shen , Brian Chen
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