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Explorations in fine-tuning Vision-Language Models (VLMs), such as Low-Rank Adaptation (LoRA) from Parameter Efficient Fine-Tuning (PEFT), have made impressive progress. However, most approaches rely on explicit weight updates, overlooking…

Machine Learning · Computer Science 2025-12-30 Mingyuan Zhang , Yue Bai , Yifan Wang , Yiyang Huang , Yun Fu

Fine-tuning large language models (LLMs) with limited data poses a practical challenge in low-resource languages, specialized domains, and constrained deployment settings. While pre-trained LLMs provide strong foundations, effective…

Computation and Language · Computer Science 2025-10-29 Marton Szep , Daniel Rueckert , Rüdiger von Eisenhart-Rothe , Florian Hinterwimmer

Unit testing plays a pivotal role in software development, improving software quality and reliability. However, generating effective test cases manually is time-consuming, prompting interest in unit testing research. Recently, Large…

Software Engineering · Computer Science 2024-12-24 Ye Shang , Quanjun Zhang , Chunrong Fang , Siqi Gu , Jianyi Zhou , Zhenyu Chen

Language models (LMs) are machine learning models designed to predict linguistic patterns by estimating the probability of word sequences based on large-scale datasets, such as text. LMs have a wide range of applications in natural language…

Protein language models (PLMs) have revolutionised computational biology through their ability to generate powerful sequence representations for diverse prediction tasks. However, their black-box nature limits biological interpretation and…

Biomolecules · Quantitative Biology 2025-04-11 Jan van Eck , Dea Gogishvili , Wilson Silva , Sanne Abeln

Going beyond mere fine-tuning of vision-language models (VLMs), learnable prompt tuning has emerged as a promising, resource-efficient alternative. Despite their potential, effectively learning prompts faces the following challenges: (i)…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Hari Chandana Kuchibhotla , Sai Srinivas Kancheti , Abbavaram Gowtham Reddy , Vineeth N Balasubramanian

Vision-language models (VLMs) have made substantial progress across a wide range of visual question answering benchmarks, spanning visual reasoning, document understanding, and multimodal dialogue. These improvements are evident in a wide…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Dhruba Ghosh , Yuhui Zhang , Ludwig Schmidt

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and to delay further progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical…

Computation and Language · Computer Science 2023-04-03 Yi Wang , Jiajun Deng , Tianzi Wang , Bo Zheng , Shoukang Hu , Xunying Liu , Helen Meng

The impressive linguistic abilities of large language models (LLMs) have recommended them as models of human sentence processing, with some conjecturing a positive 'quality-power' relationship (Wilcox et al., 2023), in which language…

Computation and Language · Computer Science 2025-05-20 Yi-Chien Lin , Hongao Zhu , William Schuler

Fine-tuning Large Language Models (LLMs) incurs considerable training costs, driving the need for data-efficient training with optimised data ordering. Human-inspired strategies offer a solution by organising data based on human learning…

Computation and Language · Computer Science 2024-11-06 Yushi Yang , Andrew M. Bean , Robert McCraith , Adam Mahdi

Large language models (LLMs) have demonstrated impressive task-solving capabilities through prompting techniques and system designs, including solving planning tasks (e.g., math proofs, basic travel planning) when sufficient data is…

Artificial Intelligence · Computer Science 2025-04-25 Wenjun Li , Changyu Chen , Pradeep Varakantham

Vision-Language Models (VLMs), such as CLIP, have already seen widespread applications. Researchers actively engage in further fine-tuning VLMs in safety-critical domains. In these domains, prediction rationality is crucial: the prediction…

Machine Learning · Computer Science 2025-02-26 Qitong Wang , Tang Li , Kien X. Nguyen , Xi Peng

We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

Biomolecules · Quantitative Biology 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang

Aligned representations across languages is a desired property in multilingual large language models (mLLMs), as alignment can improve performance in cross-lingual tasks. Typically alignment requires fine-tuning a model, which is…

Computation and Language · Computer Science 2025-07-22 Anirudh Sundar , Sinead Williamson , Katherine Metcalf , Barry-John Theobald , Skyler Seto , Masha Fedzechkina

Despite their success in many natural language tasks, solving math problems remains a significant challenge for large language models (LLMs). A large gap exists between LLMs' pass-at-one and pass-at-N performance in solving math problems,…

Computation and Language · Computer Science 2023-10-17 Yixin Liu , Avi Singh , C. Daniel Freeman , John D. Co-Reyes , Peter J. Liu

Model editing aims at selectively updating a small subset of a neural model's parameters with an interpretable strategy to achieve desired modifications. It can significantly reduce computational costs to adapt to large language models…

Computation and Language · Computer Science 2025-03-20 Shichen Li , Zhongqing Wang , Zheyu Zhao , Yue Zhang , Peifeng Li

This paper addresses the critical disconnect between prediction and decision quality in portfolio optimization by integrating Large Language Models (LLMs) with decision-focused learning. We demonstrate both theoretically and empirically…

Portfolio Management · Quantitative Finance 2025-02-04 Yoontae Hwang , Yaxuan Kong , Stefan Zohren , Yongjae Lee

Directed evolution as a widely-used engineering strategy faces obstacles in finding desired mutants from the massive size of candidate modifications. While deep learning methods learn protein contexts to establish feasible searching space,…

Quantitative Methods · Quantitative Biology 2023-04-18 Bingxin Zhou , Outongyi Lv , Kai Yi , Xinye Xiong , Pan Tan , Liang Hong , Yu Guang Wang

Contemporary Vision-Language Models (VLMs) achieve strong performance on a wide range of tasks by pairing a vision encoder with a pre-trained language model, fine-tuned for visual-text inputs. Yet despite these gains, it remains unclear how…

Computer Vision and Pattern Recognition · Computer Science 2026-02-10 Lachin Naghashyar , Hunar Batra , Ashkan Khakzar , Philip Torr , Ronald Clark , Christian Schroeder de Witt , Constantin Venhoff

Understanding biological processes, drug development, and biotechnological advancements requires a detailed analysis of protein structures and functions, a task that is inherently complex and time-consuming in traditional protein research.…

Artificial Intelligence · Computer Science 2025-04-21 Yijia Xiao , Edward Sun , Yiqiao Jin , Qifan Wang , Wei Wang