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Binding energy is a fundamental thermodynamic property that governs molecular interactions, playing a crucial role in fields such as healthcare and the natural sciences. It is particularly relevant in drug development, vaccine design, and…

Quantum Physics · Physics 2025-08-06 Erico Souza Teixeira , Lucas Barros Fernandes , Yara Rodrigues Inácio

The thermodynamics of proteins indicate that folding/unfolding takes place either through stable intermediates or through a two-state process without intermediates. The rather short folding times of the two-state process indicate that…

Condensed Matter · Physics 2016-08-31 Audun Bakk , Johan S. Hoye , Alex Hansen , Kim Sneppen , Mogens Hogh Jensen

We present a statistical mechanics treatment of the stability of globular proteins which takes explicitly into account the coupling between the protein and water degrees of freedom. This allows us to describe both the cold and the warm…

Condensed Matter · Physics 2009-10-30 Alex Hansen , Mogens H. Jensen , Kim Sneppen , Giovanni Zocchi

A comprehensive description of molecular electron transfer reactions is essential for our understanding of fundamental phenomena in bio-energetics and molecular electronics. Experimental studies of molecular systems in condensed-phase…

Quantum Physics · Physics 2021-02-04 Frank Schlawin , Manuel Gessner , Andreas Buchleitner , Tobias Schaetz , Spiros S Skourtis

The quantum-mechanical and thermodynamic properties of a 3-level molecular cooling cycle are derived. An inadequacy of earlier models is rectified in accounting for the spontaneous emission and absorption associated with the coupling to the…

Quantum Physics · Physics 2009-11-07 Jose P. Palao , Ronnie Kosloff , Jeffrey M. Gordon

The Q-cycle mechanism entering the electron and proton transport chain in oxygenic photosynthesis is an example of how biological processes can be efficiently investigated with elementary microscopic models. Here we address the problem of…

Quantum Physics · Physics 2019-11-21 Francesco Tacchino , Antonella Succurro , Oliver Ebenhöh , Dario Gerace

A low-temperature dynamical transition has been reported in several proteins. We provide the first observation of a `protein-like' dynamical transition in nonbiological aqueous environments. To this aim we exploit the popular colloidal…

We present a model to study the statistics of a single structureless quantum particle freely moving in a space at a finite temperature. It is shown that the quantum particle feels the temperature and can exchange energy with its environment…

Statistical Mechanics · Physics 2010-10-04 Jian-Ping Peng

Ultracold molecules confined in optical lattices or tweezer traps can be used to process quantum information and simulate the behaviour of many-body quantum systems. Molecules offer several advantages for these applications. They have a…

Quantum Gases · Physics 2024-01-11 Simon L. Cornish , Michael R. Tarbutt , Kaden R. A. Hazzard

The minimal set of thermodynamic control parameters consists of a statistical (thermal) and a mechanical one. These suffice to introduce all the pertinent thermodynamic variables; thermodynamic processes can then be defined as paths on this…

Statistical Mechanics · Physics 2009-11-13 Jan Birjukov , Thomas Jahnke , Günter Mahler

We present a simple model of protein folding dynamics that captures key qualitative elements recently seen in all-atom simulations. The goals of this theory are to serve as a simple formalism for gaining deeper insight into the physical…

Biological Physics · Physics 2015-05-19 Vijay S. Pande

We explain the dynamics of cold atoms, initially trapped and cooled in a magneto-optic trap, in a monochromatic stationary standing electromagnetic wave field. In the large detuning limit the system is modeled as a nonlinear quantum…

Quantum Physics · Physics 2010-12-30 Muhammad Ayub , Khalid Naseer , Manzoor Ali , Farhan Saif

Cooling atoms to ultralow temperatures has produced a wealth of opportunities in fundamental physics, precision metrology, and quantum science. The more recent application of sophisticated cooling techniques to molecules, which has been…

Atomic Physics · Physics 2017-09-21 John L Bohn , Ana Maria Rey , Jun Ye

Quantum mechanical tunneling of atoms is increasingly found to play an important role in many chemical transformations. Experimentally, atom-tunneling can be indirectly detected by temperature-independent rate constants at low temperature…

Chemical Physics · Physics 2020-09-10 Jan Meisner , Johannes Kästner

Let a general quantum many-body system at a low temperature adiabatically cross through the vicinity of the system's quantum critical point. We show that the system's temperature is significantly suppressed due to both the entropy…

Statistical Mechanics · Physics 2009-08-27 Shi-Jian Gu

We consider finite sized atomic systems with varying number of particles which have dipolar interactions among them and also under the collective driving and dissipative effect of thermal photon environment. Focusing on the simple case of…

Quantum Physics · Physics 2017-09-25 B. Çakmak , A. Manatuly , Ö. E. Müstecaplıoğlu

Potential realization of a quantum thermometer operating in the nanokelvin regime, formed by a few-fermionic mixture confined in a one-dimensional harmonic trap, is proposed. Thermal states of the system are studied theoretically from the…

Quantum Gases · Physics 2018-06-22 Marcin Płodzień , Rafał Demkowicz-Dobrzański , Tomasz Sowiński

Normal mode analysis is a widely used technique for reconstructing conformational changes of proteins from the knowledge of native structures. In this Letter, we investigate to what extent normal modes capture the salient features of the…

Statistical Mechanics · Physics 2015-05-13 Francesco Piazza , Paolo De Los Rios , Fabio Cecconi

A classical thermometer typically works by exchanging energy with the system being measured until it comes to equilibrium, at which point the readout is related to the final energy state of the thermometer. A recent paper noted that…

Quantum Physics · Physics 2016-09-07 W. K. Tham , H. Ferretti , A. V. Sadashivan , A. M. Steinberg

Allosteric regulation is often viewed as thermodynamic in nature. However protein internal motions during an enzymatic reaction cycle can be slow hopping processes over numerous potential barriers. We propose that regulating molecules may…

Biological Physics · Physics 2009-11-13 Jianhua Xing