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We present a new four-dimensional phase unwrapping approach for time-lapse quantitative phase microscopy, which allows reconstruction of optically thick objects that are optically thin in a certain temporal point and angular view. We thus…
We introduce a denoising method for four-dimensional scanning transmission electron microscopy (4D-STEM) that relies on processing local, scan position-independent electron event-sparse data stacks, called event-sparse stack denoising. This…
Liquid xenon time projection chambers offer a homogeneous detection medium with excellent intrinsic energy resolution, fast scintillation, and true three-dimensional position sensitivity, making them an attractive alternative to…
We propose a single-shot quantitative differential phase contrast (DPC) method with polarization multiplexing illumination. In the illumination module of our system, the programmable LED array is divided into four quadrants and covered with…
We demonstrate a motion-free intensity diffraction tomography technique that enables direct inversion of 3D phase and absorption from intensity-only measurements for weakly scattering samples. We derive a novel linear forward model,…
Scanning electron microscopy with polarization analysis is a powerful lab-based magnetic imaging technique offering parallel imaging of multiple magnetization components and a very high spatial resolution. However, one drawback of the…
Single image superresolution has been a popular research topic in the last two decades and has recently received a new wave of interest due to deep neural networks. In this paper, we approach this problem from a different perspective. With…
4D-STEM-based orientation and phase mapping has enabled rapid microstructure quantification that can be directly combined with standard TEM- and STEM-based imaging modes. Typically, orientation mapping is coupled with beam precession (i.e.…
Three-dimensional digital subtraction angiography (3D-DSA) is a widely adopted technique for clinical evaluation of contrast-enhanced vasculatures. The distribution of a contrast agent such as iodine is often estimated via temporal…
Based on image encoding in a serial-temporal format, optical time-stretch imaging entails a stringent requirement of state-of-the- art fast data acquisition unit in order to preserve high image resolution at an ultrahigh frame rate ---…
Digital PCR (dPCR) has revolutionized nucleic acid diagnostics by enabling absolute quantification of rare mutations and target sequences. However, current detection methodologies face challenges, as flow cytometers are costly and complex,…
In coherent diffractive imaging (CDI) the resolution of the reconstructed object is limited by the numerical aperture of the experimental setup. We present here a theoretical and numerical study for achieving super-resolution by…
The requirement of high space-time resolution and brightness is a great challenge for imaging atomic motion and making molecular movies. Important breakthroughs in ultrabright tabletop laser, x-ray and electron sources have enabled the…
By circumventing the resolution limitations of optics, coherent diffractive imaging (CDI) and ptychography are making their way into scientific fields ranging from X-ray imaging to astronomy. Yet, the need for time consuming iterative phase…
Atomic-scale characterization of spin textures in solids is essential for understanding and tuning properties of magnetic materials and devices. While high-energy electrons are employed for atomic-scale imaging of materials, they are…
In order to solve the problems of waveform distortion and signal delay by many physical and electrical systems with linear low-pass transfer characteristics with multiple complex poles, a general digital-signal-processing (DSP)-based method…
Transverse position reconstruction in a Time Projection Chamber (TPC) is crucial for accurate particle tracking and classification, and is typically accomplished using machine learning techniques. However, these methods often exhibit biases…
Atomic resolution imaging in transmission electron microscopy (TEM) and scanning TEM (STEM) of light elements in electron-transparent materials has long been a challenge. Biomolecular materials, for example, are rapidly altered when…
Quantitative phase imaging has become a topic of considerable interest in the microscopy community. We have recently described one such technique based on the use of a partitioned detection aperture, which can be operated in a single shot…
In this work, issues in phase retrieval in the coherent diffractive imaging (CDI) technique, from discussion on parameters for setting up a CDI experiment to evaluation of the goodness of the final reconstruction, are discussed. The…