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Related papers: Diffusion-HMC: Parameter Inference with Diffusion-…

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Cosmological simulations play a crucial role in elucidating the effect of physical parameters on the statistics of fields and on constraining parameters given information on density fields. We leverage diffusion generative models to address…

Cosmology and Nongalactic Astrophysics · Physics 2023-12-13 Nayantara Mudur , Carolina Cuesta-Lazaro , Douglas P. Finkbeiner

This tutorial provides an in-depth guide on inference-time guidance and alignment methods for optimizing downstream reward functions in diffusion models. While diffusion models are renowned for their generative modeling capabilities,…

Artificial Intelligence · Computer Science 2025-01-22 Masatoshi Uehara , Yulai Zhao , Chenyu Wang , Xiner Li , Aviv Regev , Sergey Levine , Tommaso Biancalani

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

In the era of precision cosmology, the ability to generate accurate and large-scale galaxy catalogs is crucial for advancing our understanding of the universe. With the flood of cosmological data from current and upcoming missions,…

Cosmology and Nongalactic Astrophysics · Physics 2024-12-13 Tanner Sether , Elena Giusarma , Mauricio Reyes-Hurtado

Next-generation galaxy surveys promise unprecedented precision in testing gravity at cosmological scales. However, realising this potential requires accurately modelling the non-linear cosmic web. We address this challenge by exploring…

Cosmology and Nongalactic Astrophysics · Physics 2025-08-20 Julieth Katherine Riveros , Paola Saavedra , Hector J. Hortua , Jorge Enrique Garcia-Farieta , Ivan Olier

We propose a hybrid generative model for efficient sampling of high-dimensional, multimodal probability distributions for Bayesian inference. Traditional Monte Carlo methods, such as the Metropolis-Hastings and Langevin Monte Carlo sampling…

Machine Learning · Statistics 2025-05-14 Hoang Tran , Zezhong Zhang , Feng Bao , Dan Lu , Guannan Zhang

Discrete diffusion models are a class of generative models that produce samples from an approximated data distribution within a discrete state space. Often, there is a need to target specific regions of the data distribution. Current…

Machine Learning · Computer Science 2025-09-03 Cheuk Kit Lee , Paul Jeha , Jes Frellsen , Pietro Lio , Michael Samuel Albergo , Francisco Vargas

Divide-and-conquer MCMC is a strategy for parallelising Markov Chain Monte Carlo sampling by running independent samplers on disjoint subsets of a dataset and merging their output. An ongoing challenge in the literature is to efficiently…

Machine Learning · Statistics 2024-06-18 C. Trojan , P. Fearnhead , C. Nemeth

We introduce Preconditioned Monte Carlo (PMC), a novel Monte Carlo method for Bayesian inference that facilitates efficient sampling of probability distributions with non-trivial geometry. PMC utilises a Normalising Flow (NF) in order to…

Instrumentation and Methods for Astrophysics · Physics 2022-08-24 Minas Karamanis , Florian Beutler , John A. Peacock , David Nabergoj , Uros Seljak

Diffusion models offer stable training and state-of-the-art performance for deep generative modeling tasks. Here, we consider their use in the context of multivariate subsurface modeling and probabilistic inversion. We first demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Roberto Miele , Niklas Linde

A diffusion Monte Carlo algorithm is introduced that can determine the correct nodal structure of the wave function of a few-fermion system and its ground-state energy without an uncontrolled bias. This is achieved by confining signed…

Computational Physics · Physics 2020-02-05 Alexander A. Kunitsa , So Hirata

Galaxies are biased tracers of the underlying cosmic web, which is dominated by dark matter components that cannot be directly observed. Galaxy formation simulations can be used to study the relationship between dark matter density fields…

Cosmology and Nongalactic Astrophysics · Physics 2024-03-19 Victoria Ono , Core Francisco Park , Nayantara Mudur , Yueying Ni , Carolina Cuesta-Lazaro , Francisco Villaescusa-Navarro

To sample from a general target distribution $p_*\propto e^{-f_*}$ beyond the isoperimetric condition, Huang et al. (2023) proposed to perform sampling through reverse diffusion, giving rise to Diffusion-based Monte Carlo (DMC).…

Machine Learning · Statistics 2024-01-15 Xunpeng Huang , Difan Zou , Hanze Dong , Yian Ma , Tong Zhang

We introduce a diffusion-based generative model to describe the distribution of galaxies in our Universe directly as a collection of points in 3-D space (coordinates) optionally with associated attributes (e.g., velocities and masses),…

Cosmology and Nongalactic Astrophysics · Physics 2024-12-24 Carolina Cuesta-Lazaro , Siddharth Mishra-Sharma

Hamiltonian Monte Carlo has emerged as a standard tool for posterior computation. In this article, we present an extension that can efficiently explore target distributions with discontinuous densities. Our extension in particular enables…

Computation · Statistics 2020-06-09 Akihiko Nishimura , David Dunson , Jianfeng Lu

We introduce a deep generative framework for high-dimensional Bayesian inference that enables efficient posterior sampling. As telescopes and simulations rapidly expand the volume and resolution of astrophysical data, fast simulation-based…

Instrumentation and Methods for Astrophysics · Physics 2026-03-06 Hadi Sotoudeh , Pablo Lemos , Laurence Perreault-Levasseur

Hamiltonian Monte Carlo (HMC) is a state of the art method for sampling from distributions with differentiable densities, but can converge slowly when applied to challenging multimodal problems. Running HMC with a time varying Hamiltonian,…

Machine Learning · Statistics 2026-02-26 Reuben Cohn-Gordon , Uroš Seljak , Dries Sels

Traditional gradient-based sampling methods, like standard Hamiltonian Monte Carlo, require that the desired target distribution is continuous and differentiable. This limits the types of models one can define, although the presented models…

Computation · Statistics 2025-04-28 Jimmy Huy Tran , Tore Selland Kleppe

Crucial to many measurements at the LHC is the use of correlated multi-dimensional information to distinguish rare processes from large backgrounds, which is complicated by the poor modeling of many of the crucial backgrounds in Monte Carlo…

High Energy Physics - Phenomenology · Physics 2025-11-26 Oz Amram , Manuel Szewc

Parameter inference is a fundamental problem in data-driven modeling. Given observed data that is believed to be a realization of some parameterized model, the aim is to find parameter values that are able to explain the observed data. In…

Data Structures and Algorithms · Computer Science 2016-04-20 Carlo Albert , Simone Ulzega , Ruedi Stoop
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