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Understanding mechanosensitivity, i.e. how cells sense the stiffness of their environment is very important, yet there is a fundamental difficulty in understanding its mechanism: to measure an elastic modulus one requires two points of…

Cell Behavior · Quantitative Biology 2015-06-17 Matteo Escude , Michelle K. Rigozzi , Eugene M. Terentjev

Tumor segmentation in multimodal medical images has seen a growing trend towards deep learning based methods. Typically, studies dealing with this topic fuse multimodal image data to improve the tumor segmentation contour for a single…

Image and Video Processing · Electrical Eng. & Systems 2020-09-25 Theresa Neubauer , Maria Wimmer , Astrid Berg , David Major , Dimitrios Lenis , Thomas Beyer , Jelena Saponjski , Katja Bühler

State-space models (SSMs) have recently shown promise in capturing long-range dependencies with subquadratic computational complexity, making them attractive for various applications. However, purely SSM-based models face critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Abdelrahman Shaker , Syed Talal Wasim , Salman Khan , Juergen Gall , Fahad Shahbaz Khan

The work proposes an image segmentation algorithm that isolates slender regions in three-dimensional microstructures. Characterizing slender regions in material microstructures is an extremely important aspect in material science because…

Data Analysis, Statistics and Probability · Physics 2025-03-13 Vinit Vijay Deshpande , Romana Piat

Recently, Mamba-based methods have become popular in medical image segmentation due to their lightweight design and long-range dependency modeling capabilities. However, current segmentation methods frequently encounter challenges in fetal…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Caixu Xu , Junming Wei , Huizhen Chen , Pengchen Liang , Bocheng Liang , Ying Tan , Xintong Wei

A study of parameter sensitivity of nuclear energy density functionals, initiated in the first part of this work \cite{NV.16}, is extended by the inclusion of data on ground-state properties of finite nuclei in the application of the…

Nuclear Theory · Physics 2017-05-24 Tamara Nikšić , Marko Imbrišak , Dario Vretenar

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

We study the many-body localization (MBL) transition in interacting fermionic systems on disordered one-dimensional lattices using a physics-informed machine-learning framework. Instead of feeding full many-body wave functions into the…

Disordered Systems and Neural Networks · Physics 2026-03-24 Siqi Dai , Tian-Cheng Yi , Xingbo Wei , Yunbo Zhang

Robotic materials are multi-robot systems formulated to leverage the low-order computation and actuation of the constituents to manipulate the high-order behavior of the entire material. We study the behaviors of ensembles composed of smart…

Robotics · Computer Science 2018-02-15 Ross Warkentin , William Savoie , Daniel I. Goldman

Many-body localization (MBL) is a novel prototype of ergodicity breaking due to the emergence of local integrals of motion (LIOMs) in a disordered interacting quantum system. To better understand the role played by the existence of such…

Disordered Systems and Neural Networks · Physics 2022-08-10 S. Adami , M. Amini , M. Soltani

Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the…

Subcellular Processes · Quantitative Biology 2018-06-13 Bryan Kaye , Olivia Stiehl , Peter J. Foster , Michael J. Shelley , Daniel J. Needleman , Sebastian Fürthauer

Body tissue composition is a long-known biomarker with high diagnostic and prognostic value in cardiovascular, oncological and orthopaedic diseases, but also in rehabilitation medicine or drug dosage. In this study, the aim was to develop a…

Image and Video Processing · Electrical Eng. & Systems 2020-10-22 Sven Koitka , Lennard Kroll , Eugen Malamutmann , Arzu Oezcelik , Felix Nensa

Magnetic resonance imaging (MRI) is the non-invasive modality of choice for body tissue composition analysis due to its excellent soft tissue contrast and lack of ionizing radiation. However, quantification of body composition requires an…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Ismail Irmakci , Sarfaraz Hussein , Aydogan Savran , Rita R. Kalyani , David Reiter , Chee W. Chia , Kenneth W. Fishbein , Richard G. Spencer , Luigi Ferrucci , Ulas Bagci

Recent advances in multiplex imaging have enabled researchers to locate different types of cells within a tissue sample. This is especially relevant for tumor immunology, as clinical regimes corresponding to different stages of disease or…

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou

Quantitative magnetization transfer (MT) imaging enables non-invasive characterization of the macromolecular environment of tissues. However, recent work has highlighted that the quantification of MT parameters exhibits orientation…

Medical Physics · Physics 2025-10-06 Zijian Gao , Ziqiang Yu , Ziqin Zhou , Jian Hou , Baiyan Jiang , Michael Ong , Weitian Chen

Cells rely on focal adhesions (FAs) to carry out a variety of important tasks, including motion, environmental sensing, and adhesion to the extracellular matrix. Although attaining a fundamental characterization of FAs is a compelling goal,…

This study introduces a novel formulation to enhance Support Vector Machines (SVMs) in handling class imbalance and noise. Unlike the conventional Soft Margin SVM, which penalizes the magnitude of constraint violations, the proposed model…

Machine Learning · Computer Science 2025-03-20 Seyed Mojtaba Mohasel , Hamidreza Koosha

Computer-aided diagnosis (CAD) has long become an integral part of radiological management of breast disease, facilitating a number of important clinical applications, including quantitative assessment of breast density and early detection…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Hossein Soleimani , Oleg V. Michailovich

We analyze the "eigenbundle" (localization bundle) of certain Hilbert modules over bounded symmetric domains of rank $r,$ giving rise to complex-analytic fibre spaces which are stratified of length $r+1.$ The fibres are described in terms…

Functional Analysis · Mathematics 2022-05-26 Harald Upmeier