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The era of Large Language Models (LLMs) presents a new opportunity for interpretability--agentic interpretability: a multi-turn conversation with an LLM wherein the LLM proactively assists human understanding by developing and leveraging a…

Artificial Intelligence · Computer Science 2025-06-17 Been Kim , John Hewitt , Neel Nanda , Noah Fiedel , Oyvind Tafjord

This paper explores the integration of two AI subdisciplines employed in the development of artificial agents that exhibit intelligent behavior: Large Language Models (LLMs) and Cognitive Architectures (CAs). We present three integration…

Artificial Intelligence · Computer Science 2023-09-29 Oscar J. Romero , John Zimmerman , Aaron Steinfeld , Anthony Tomasic

The incorporation of Large Language Models (LLMs) such as the GPT series into diverse sectors including healthcare, education, and finance marks a significant evolution in the field of artificial intelligence (AI). The increasing demand for…

Human-Computer Interaction · Computer Science 2024-07-18 Guangzhi Sun , Xiao Zhan , Jose Such

Advancements in Multimodal Large Language Models (MLLMs) have improved human motion understanding. However, these models remain constrained by their "instruct-only" nature, lacking interactivity and adaptability for diverse analytical…

Artificial Intelligence · Computer Science 2025-02-28 Lei Li , Sen Jia , Jianhao Wang , Zhaochong An , Jiaang Li , Jenq-Neng Hwang , Serge Belongie

This study focuses on emotion-sensitive spoken dialogue in human-machine speech interaction. With the advancement of Large Language Models (LLMs), dialogue systems can handle multimodal data, including audio. Recent models have enhanced the…

Sound · Computer Science 2024-07-30 Hongfei Xue , Yuhao Liang , Bingshen Mu , Shiliang Zhang , Mengzhe Chen , Qian Chen , Lei Xie

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Large Language Models' (LLMs) ability to converse naturally is empowered by their ability to empathetically understand and respond to their users. However, emotional experiences are shaped by demographic and cultural contexts. This raises…

Computation and Language · Computer Science 2025-10-28 Ananya Malik , Nazanin Sabri , Melissa Karnaze , Mai Elsherief

Large Language Models (LLMs) have become a popular interface for human-AI interaction, supporting information seeking and task assistance through natural, multi-turn dialogue. To respond to users within multi-turn dialogues, the…

Computation and Language · Computer Science 2026-04-16 Fengran Mo , Yifan Gao , Sha Li , Hansi Zeng , Xin Liu , Zhaoxuan Tan , Xian Li , Jianshu Chen , Dakuo Wang , Meng Jiang

Large Language Models (LLMs) have demonstrated great potential for conducting diagnostic conversations but evaluation has been largely limited to language-only interactions, deviating from the real-world requirements of remote care…

Healthcare systems around the world are grappling with issues like inefficient diagnostics, rising costs, and limited access to specialists. These problems often lead to delays in treatment and poor health outcomes. Most current AI and deep…

Artificial Intelligence · Computer Science 2025-12-22 Maliha Tabassum , M Shamim Kaiser

The development of believable, natural, and interactive digital artificial agents is a field of growing interest. Theoretical uncertainties and technical barriers present considerable challenges to the field, particularly with regards to…

Artificial Intelligence · Computer Science 2023-09-12 Maximilian Croissant , Madeleine Frister , Guy Schofield , Cade McCall

Evaluating large language models (LLM) in clinical scenarios is crucial to assessing their potential clinical utility. Existing benchmarks rely heavily on static question-answering, which does not accurately depict the complex, sequential…

Human-Computer Interaction · Computer Science 2025-05-27 Samuel Schmidgall , Rojin Ziaei , Carl Harris , Eduardo Reis , Jeffrey Jopling , Michael Moor

The use of large language models (LLMs) for Mental Health Question Answering (MHQA) offers a promising way to alleviate shortages in mental health resources. However, prior work has mainly relied on Cognitive Behavioral Therapy (CBT) and…

Computation and Language · Computer Science 2026-03-10 Lanqing Du , Yunong Li , YuJie Long , Shihong Chen

Large language models (LLMs) are revolutionizing healthcare by improving diagnosis, patient care, and decision support through interactive communication. More recently, they have been applied to analyzing physiological time-series like…

Computation and Language · Computer Science 2025-04-30 Mohammad Feli , Iman Azimi , Pasi Liljeberg , Amir M. Rahmani

The integration of Large Language Models (LLMs) into interactive systems opens new opportunities for adaptive user experiences, yet it also raises challenges regarding accessibility, explainability, and normative compliance. This paper…

Human-Computer Interaction · Computer Science 2026-01-13 Blessing Jerry , Lourdes Moreno , Virginia Francisco , Raquel Hervas

Conversational agents powered by large language models (LLM) have increasingly been utilized in the realm of mental well-being support. However, the implications and outcomes associated with their usage in such a critical field remain…

Human-Computer Interaction · Computer Science 2023-08-01 Zilin Ma , Yiyang Mei , Zhaoyuan Su

The integration of a complex set of Electronic Design Automation (EDA) tools to enhance interoperability is a critical concern for circuit designers. Recent advancements in large language models (LLMs) have showcased their exceptional…

Hardware Architecture · Computer Science 2024-09-24 Zhuolun He , Haoyuan Wu , Xinyun Zhang , Xufeng Yao , Su Zheng , Haisheng Zheng , Bei Yu

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

Emotional and cognitive factors are essential for understanding mental health disorders. However, existing methods often treat multi-modal data as classification tasks, limiting interpretability especially for emotion and cognition.…

Multimedia · Computer Science 2026-03-03 Zhiyuan Zhou , Yanrong Guo , Shijie Hao

Personalized support is essential to fulfill individuals' emotional needs and sustain their mental well-being. Large language models (LLMs), with great customization flexibility, hold promises to enable individuals to create their own…

Human-Computer Interaction · Computer Science 2025-05-01 Xi Zheng , Zhuoyang Li , Xinning Gui , Yuhan Luo
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