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When a system deviates from equilibrium, it is possible to manipulate and control it to drive it towards equilibrium within a finite time $t_f$, even reducing its natural relaxation time scale $\tau_{relax}$. Although numerous theoretical…

Statistical Mechanics · Physics 2024-02-26 Diego Rengifo , Gabriel Téllez

Stochastic reaction network models are often used to explain and predict the dynamics of gene regulation in single cells. These models usually involve several parameters, such as the kinetic rates of chemical reactions, that are not…

Computation · Statistics 2020-01-07 Thomas A. Catanach , Huy D. Vo , Brian Munsky

We propose a statistical mechanics for a general class of stationary and metastable equilibrium states. For this purpose, the Gibbs extremal conditions are slightly modified in order to be applied to a wide class of non-equilibrium states.…

Statistical Mechanics · Physics 2017-10-20 A. Cabo , S. Curilef , A. Gonzalez , N. G. Cabo-Bizet , C. A. Vera

As far as we know, there is no flat-histogram algorithm to sample the stationary distribution of non-equilibrium stochastic processes. The present work addresses this gap by introducing a generalization of the Wang-Landau algorithm, applied…

Statistical Mechanics · Physics 2026-02-27 L. M. C. Alencar , T. F. A. Alves , G. A. Alves , F. W. S. Lima , A. Macedo-Filho , R. S. Ferreira

Biological systems with intertwined feedback loops pose a challenge to mathematical modeling efforts. Moreover, rare events, such as mutation and extinction, complicate system dynamics. Stochastic simulation algorithms are useful in…

Quantitative Methods · Quantitative Biology 2018-12-10 Alfonso Landeros , Timothy Stutz , Kevin L. Keys , Alexander Alekseyenko , Janet S. Sinsheimer , Kenneth Lange , Mary Sehl

We investigate quantum reaction-diffusion systems in one-dimension with bosonic particles that coherently hop in a lattice, and when brought in range react dissipatively. Such reactions involve binary annihilation ($A + A \to \emptyset$)…

Statistical Mechanics · Physics 2024-05-20 Shiphrah Rowlands , Igor Lesanovsky , Gabriele Perfetto

In the context of unitary evolution of a generic quantum system interrupted at random times with non-unitary evolution due to interactions with either the external environment or a measuring apparatus, we adduce a general theoretical…

Quantum Physics · Physics 2022-05-10 Debraj Das , Sushanta Dattagupta , Shamik Gupta

In this study, we introduce a sensitivity analysis methodology for stochastic systems in chemistry, where dynamics are often governed by random processes. Our approach is based on gradient estimation via finite differences, averaging…

Quantitative Methods · Quantitative Biology 2026-01-12 Erika M. Herrera Machado , Jakob L. Andersen , Rolf Fagerberg , Daniel Merkle

The application of the quasi-steady-state approximation to the Michaelis-Menten reaction embedded in large open chemical reaction networks is a popular model reduction technique in deterministic and stochastic simulations of biochemical…

Statistical Mechanics · Physics 2013-05-28 Philipp Thomas , Arthur V. Straube , Ramon Grima

The stochastic limit approximation method for ``rapid'' decay is presented, where the damping rate \gamma is comparable to the system frequency \Omega, i.e., \gamma \sim \Omega, whereas the usual stochastic limit approximation is applied…

Quantum Physics · Physics 2016-09-08 Gen Kimura , Kazuya Yuasa , Kentaro Imafuku

We present a quantum algorithm based on repeated measurement to solve initial-value problems for nonlinear ordinary differential equations (ODEs), which may be generated from partial differential equations in plasma physics. We map a…

Quantum Physics · Physics 2025-04-30 Joseph Andress , Alexander Engel , Yuan Shi , Scott Parker

A Bayesian non-parametric framework for studying time-to-event data is proposed, where the prior distribution is allowed to depend on an additional random source, and may update with the sample size. Such scenarios are natural, for…

Methodology · Statistics 2025-05-06 Martin Bladt , Jorge González Cázares

Various kinetic Monte Carlo algorithms become inefficient when some of the population sizes in a system are large, which gives rise to a large number of reaction events per unit time. Here, we present a new acceleration algorithm based on…

Quantitative Methods · Quantitative Biology 2019-07-24 Yen Ting Lin , Song Feng , William S. Hlavacek

Many approaches to modelling reaction-diffusion systems with anomalous transport rely on deterministic equations and ignore fluctuations arising due to finite particle numbers. Starting from an individual-based model we use a…

Statistical Mechanics · Physics 2019-05-29 Joseph W. Baron , Tobias Galla

We consider diffusion-limited reactions A_i + A_j -> 0 (1 <= i < j <= q) in d space dimensions. For q > 2 and d >= 2 we argue that the asymptotic density decay for such mutual annihilation processes with equal rates and initial densities is…

Statistical Mechanics · Physics 2009-11-07 Olivier Deloubriere , Henk Hilhorst , Uwe C. Tauber

There is great potential to be explored regarding the use of agent-based modelling and simulation as an alternative paradigm to investigate early-stage cancer interactions with the immune system. It does not suffer from some limitations of…

Multiagent Systems · Computer Science 2015-06-22 Grazziela P Figueredo , Peer-Olaf Siebers , Markus R Owen , Jenna Reps , Uwe Aickelin

We introduce a stochastic nonlocal reaction--diffusion model arising in tumour dynamics. Spatial dispersal is described by the fractional Laplacian, accounting for anomalous diffusion and long--range relocation events. The system is…

We present a novel multiscale simulation approach for modeling stochasticity in chemical reaction networks. The approach seamlessly integrates exact-stochastic and "leaping" methodologies into a single "partitioned leaping" algorithmic…

Chemical Physics · Physics 2009-11-11 Leonard A. Harris , Paulette Clancy

Biochemical systems are inherently stochastic, particularly those with small-molecule populations. The spatial distribution of molecules plays a critical role and requires the inclusion of spatial coordinates in their analysis. Stochastic…

Molecular Networks · Quantitative Biology 2025-05-15 Manuel Eduardo Hernández-García , Eduardo Moreno-Barbosa , Jorge Velázquez-Castro

While there are many well-known and extensively tested results involving diffusion-limited binary reactions, reactions involving subdiffusive reactant species are far less understood. Subdiffusive motion is characterized by a mean square…

Statistical Mechanics · Physics 2009-11-11 J. J. Ruiz-Lorenzo , S. B. Yuste , Katja Lindenberg
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