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In recent advances in solving the problem of transmission network expansion planning, the use of robust optimization techniques has been put forward, as an alternative to stochastic mathematical programming methods, to make the problem…

Computational Engineering, Finance, and Science · Computer Science 2016-09-28 Roberto Minguez , Raquel Garcia-Bertrand

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…

Traditionally, optimization of radiation therapy (RT) treatment plans has been done before the initiation of RT course, using population-wide estimates for patients' response to therapy. However, recent technological advancements have…

Medical Physics · Physics 2021-02-15 Stefan C. M. ten Eikelder , Ali Ajdari , Thomas Bortfeld , Dick den Hertog

Objective: Accurate probability estimates are essential for the safe deployment of medical image segmentation models in clinical decision-making. However, modern deep segmentation networks are often poorly calibrated, a problem exacerbated…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Meritxell Riera-Marín , Javier García López , Júlia Rodríguez-Comas , Miguel A. González Ballester , Adrian Galdran

We advocate an optimization procedure for variable density sampling in the context of compressed sensing. In this perspective, we introduce a minimization problem for the coherence between the sparsity and sensing bases, whose solution…

Information Theory · Computer Science 2011-09-29 Gilles Puy , Pierre Vandergheynst , Yves Wiaux

We consider the problem of matrix completion on an $n \times m$ matrix. We introduce the problem of Interpretable Matrix Completion that aims to provide meaningful insights for the low-rank matrix using side information. We show that the…

Optimization and Control · Mathematics 2020-03-05 Dimitris Bertsimas , Michael Lingzhi Li

We present an amelioration of current known algorithms for optimal spectral partitioning problems. The idea is to use the advantage of a representation using density functions while decreasing the computational time. This is done by…

Optimization and Control · Mathematics 2017-05-25 Beniamin Bogosel

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu

Radiotherapy (RT) is a critical cancer treatment, with volumetric modulated arc therapy (VMAT) being a commonly used technique that enhances dose conformity by dynamically adjusting multileaf collimator (MLC) positions and monitor units…

Medical Physics · Physics 2025-06-26 Stefanos Achlatis , Efstratios Gavves , Jan-Jakob Sonke

Vision-Language Models (VLMs) demand substantial computational resources during inference, largely due to the extensive visual input tokens for representing visual information. Previous studies have noted that visual tokens tend to receive…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Cheng Yang , Yang Sui , Jinqi Xiao , Lingyi Huang , Yu Gong , Chendi Li , Jinghua Yan , Yu Bai , Ponnuswamy Sadayappan , Xia Hu , Bo Yuan

Many modern iterative solvers for large-scale tomographic reconstruction incur two major computational costs per iteration: expensive forward/adjoint projections to update the data fidelity term and costly proximal computations for the…

Optimization and Control · Mathematics 2026-02-11 Evangelos Papoutsellis , Zeljko Kereta , Kostas Papafitsoros

In many randomized experiments, the treatment effect of the long-term metric (i.e. the primary outcome of interest) is often difficult or infeasible to measure. Such long-term metrics are often slow to react to changes and sufficiently…

Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…

Temporally modulated pulsed radiotherapy (TMPRT) delivers conventional fraction doses of radiation using temporally separated pulses of low doses (<30 cGy) yielding fraction-effective dose rates of around 6.7 cGy/min with the goal to…

Medical Physics · Physics 2026-01-13 Christian Velten , Adam Bayliss , Jiayi Huang , Wolfgang A. Tomé

Background and Purpose: Increasing the number of arcs in volumetric modulated arc therapy (VMAT) allows for better intensity modulation and may improve plan quality. However, this leads to longer delivery times, which may cause patient…

Medical Physics · Physics 2025-10-31 Nathan Torelli , Madalyne Day , Jan Unkelbach

In this paper we study the split minimization problem that consists of two constrained minimization problems in two separate spaces that are connected via a linear operator that maps one space into the other. To handle the data of such a…

Optimization and Control · Mathematics 2024-05-06 Francisco J. Aragón-Artacho , Yair Censor , Aviv Gibali , David Torregrosa-Belén

Recent policy optimization approaches (Schulman et al., 2015a; 2017) have achieved substantial empirical successes by constructing new proxy optimization objectives. These proxy objectives allow stable and low variance policy learning, but…

Machine Learning · Computer Science 2020-02-24 Marcin B. Tomczak , Dongho Kim , Peter Vrancx , Kee-Eung Kim

High-quality labeled data is essential to successfully train supervised machine learning models. Although a large amount of unlabeled data is present in the medical domain, labeling poses a major challenge: medical professionals who can…

Machine Learning · Computer Science 2020-04-21 Abhijeet Parida , Aadhithya Sankar , Rami Eisawy , Tom Finck , Benedikt Wiestler , Franz Pfister , Julia Moosbauer

We present a method of directly optimizing on deviations in clinical goal values in radiation therapy treatment planning. Using a new mathematical framework in which metrics derived from the dose-volume histogram are regarded as functionals…

Medical Physics · Physics 2021-09-07 Tianfang Zhang , Rasmus Bokrantz , Jimmy Olsson

Robust optimization (RO) is a powerful paradigm for decision making under uncertainty. Existing algorithms for solving RO, including the reformulation approach and the cutting-plane method, do not scale well, hindering the application of RO…

Optimization and Control · Mathematics 2024-04-09 Kai Tu , Zhi Chen , Man-Chung Yue
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