English
Related papers

Related papers: Scalable Amortized GPLVMs for Single Cell Transcri…

200 papers

We introduce a Gaussian Prototype Layer for gradient-based prototype learning and demonstrate two novel network architectures for explainable segmentation one of which relies on region proposals. Both models are evaluated on agricultural…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Michael Gerstenberger , Steffen Maaß , Peter Eisert , Sebastian Bosse

Variational autoencoders employ an amortized inference model to approximate the posterior of latent variables. However, such amortized variational inference faces two challenges: (1) the limited posterior expressiveness of fully-factorized…

Machine Learning · Computer Science 2022-12-01 Yookoon Park , Chris Dongjoo Kim , Gunhee Kim

The digital telecommunications receiver is an important context for inference methodology, the key objective being to minimize the expected loss function in recovering the transmitted information. For that criterion, the optimal decision is…

Information Theory · Computer Science 2018-11-07 Viet Hung Tran

We consider the problem of inferring a latent function in a probabilistic model of data. When dependencies of the latent function are specified by a Gaussian process and the data likelihood is complex, efficient computation often involve…

Machine Learning · Statistics 2018-07-23 Martin Tegner , Benjamin Bloem-Reddy , Stephen Roberts

Latent class analysis is used to perform model based clustering for multivariate categorical responses. Selection of the variables most relevant for clustering is an important task which can affect the quality of clustering considerably.…

Computation · Statistics 2016-06-17 Arthur White , Jason Wyse , Thomas Brendan Murphy

Many statistical methods have been proposed for variable selection in the past century, but few balance inference and prediction tasks well. Here we report on a novel variable selection approach called Penalized regression with…

Methodology · Statistics 2021-06-16 Yi Zuo , Thomas G. Stewart , Jeffrey D. Blume

The ability to manipulate complex systems, such as the brain, to modify specific outcomes has far-reaching implications, particularly in the treatment of psychiatric disorders. One approach to designing appropriate manipulations is to…

Machine Learning · Statistics 2024-09-05 Austin Talbot , Corey J Keller , David E Carlson , Alex V Kotlar

Existing partial sequence labeling models mainly focus on max-margin framework which fails to provide an uncertainty estimation of the prediction. Further, the unique ground truth disambiguation strategy employed by these models may include…

Machine Learning · Computer Science 2022-09-21 Xiaolei Lu , Tommy W. S. Chow

Recently, particle-based variational inference (ParVI) methods have gained interest because they can avoid arbitrary parametric assumptions that are common in variational inference. However, many ParVI approaches do not allow arbitrary…

Machine Learning · Computer Science 2021-08-12 Neale Ratzlaff , Qinxun Bai , Li Fuxin , Wei Xu

Multivariate time series with missing values are common in areas such as healthcare and finance, and have grown in number and complexity over the years. This raises the question whether deep learning methodologies can outperform classical…

Machine Learning · Statistics 2020-02-21 Vincent Fortuin , Dmitry Baranchuk , Gunnar Rätsch , Stephan Mandt

Molecular and genomic technological advancements have greatly enhanced our understanding of biological processes by allowing us to quantify key biological variables such as gene expression, protein levels, and microbiome compositions. These…

Methodology · Statistics 2024-06-12 Mingyu Du , Kevin Johnston , Veronica Berrocal , Wei Li , Xiangmin Xu , Zhaoxia Yu

The recently introduced class of simultaneous graphical dynamic linear models (SGDLMs) defines an ability to scale on-line Bayesian analysis and forecasting to higher-dimensional time series. This paper advances the methodology of SGDLMs,…

Applications · Statistics 2022-06-07 Lutz F. Gruber , Mike West

Dimensionality reduction (DR) offers a useful representation of complex high-dimensional data. Recent DR methods focus on hyperbolic geometry to derive a faithful low-dimensional representation of hierarchical data. However, existing…

Machine Learning · Computer Science 2026-04-24 Koshi Watanabe , Keisuke Maeda , Takahiro Ogawa , Miki Haseyama

Gaussian process (GP) regression is a flexible, nonparametric approach to regression that naturally quantifies uncertainty. In many applications, the number of responses and covariates are both large, and a goal is to select covariates that…

Methodology · Statistics 2022-10-12 Jian Cao , Joseph Guinness , Marc G. Genton , Matthias Katzfuss

Single-cell RNA sequencing has transformed biology by enabling the measurement of gene expression at cellular resolution, providing information for cell types, states, and disease contexts. Recently, single-cell foundation models have…

Machine Learning · Computer Science 2025-10-13 Oussama Kharouiche , Aris Markogiannakis , Xiao Fei , Michail Chatzianastasis , Michalis Vazirgiannis

Finding relevant and high-quality datasets to train machine learning models is a major bottleneck for practitioners. Furthermore, to address ambitious real-world use-cases there is usually the requirement that the data come labelled with…

Machine Learning · Computer Science 2023-10-05 Georgios Papadopoulos , Fran Silavong , Sean Moran

This paper represents a preliminary (pre-reviewing) version of a sublinear variational algorithm for isotropic Gaussian mixture models (GMMs). Further developments of the algorithm for GMMs with diagonal covariance matrices (instead of…

Machine Learning · Statistics 2022-06-22 Florian Hirschberger , Dennis Forster , Jörg Lücke

This paper proposes a hybrid basis function construction method (GP-RVM) for Symbolic Regression problem, which combines an extended version of Genetic Programming called Kaizen Programming and Relevance Vector Machine to evolve an optimal…

Neural and Evolutionary Computing · Computer Science 2018-08-28 Hossein Izadi Rad , Ji Feng , Hitoshi Iba

This paper introduces Least Volume (LV)--a simple yet effective regularization method inspired by geometric intuition--that reduces the number of latent dimensions required by an autoencoder without prior knowledge of the dataset's…

Machine Learning · Computer Science 2025-09-26 Qiuyi Chen , Cashen Diniz , Mark Fuge

Extracting insight from the enormous quantity of data generated from molecular simulations requires the identification of a small number of collective variables whose corresponding low-dimensional free-energy landscape retains the essential…

Chemical Physics · Physics 2019-12-30 Yasemin Bozkurt Varolgunes , Tristan Bereau , Joseph F. Rudzinski