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The scarcity of annotated surgical data poses a significant challenge for developing deep learning systems in computer-assisted interventions. While diffusion models can synthesize realistic images, they often suffer from data memorization,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Danush Kumar Venkatesh , Stefanie Speidel

Diffusion model has become a main paradigm for synthetic data generation in many subfields of modern machine learning, including computer vision, language model, or speech synthesis. In this paper, we leverage the power of diffusion model…

Machine Learning · Statistics 2023-11-20 Namjoon Suh , Xiaofeng Lin , Din-Yin Hsieh , Merhdad Honarkhah , Guang Cheng

Causal inference is essential for developing and evaluating medical interventions, yet real-world medical datasets are often difficult to access due to regulatory barriers. This makes synthetic data a potentially valuable asset that enables…

Machine Learning · Computer Science 2025-10-22 Harry Amad , Zhaozhi Qian , Dennis Frauen , Julianna Piskorz , Stefan Feuerriegel , Mihaela van der Schaar

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Training machine learning models on massive datasets is expensive and time-consuming. Dataset distillation addresses this by creating a small synthetic dataset that achieves the same performance as the full dataset. Recent methods use…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Jeffrey A. Chan-Santiago , Mubarak Shah

Over the last three to five years, it has become possible to generate machine learning synthetic data for healthcare-related uses. However, concerns have been raised about potential negative factors associated with the possibilities of…

This paper presents a comprehensive systematic review of generative models (GANs, VAEs, DMs, and LLMs) used to synthesize various medical data types, including imaging (dermoscopic, mammographic, ultrasound, CT, MRI, and X-ray), text,…

Tabular data is one of the most prevalent and important data formats in real-world applications such as healthcare, finance, and education. However, its effective use in machine learning is often constrained by data scarcity, privacy…

Machine Learning · Computer Science 2025-07-18 Ruxue Shi , Yili Wang , Mengnan Du , Xu Shen , Yi Chang , Xin Wang

Deep generative models and synthetic medical data have shown significant promise in addressing key challenges in healthcare, such as privacy concerns, data bias, and the scarcity of realistic datasets. While research in this area has grown…

Machine Learning · Computer Science 2025-02-05 Krishan Agyakari Raja Babu , Supriti Mulay , Om Prabhu , Mohanasankar Sivaprakasam

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

The use of synthetic data is recognized as a crucial step in the development of neural network-based Artificial Intelligence (AI) systems. While the methods for generating synthetic data for AI applications in other domains have a role in…

Artificial Intelligence · Computer Science 2023-03-17 Gary An , Chase Cockrell

The acquisition of large-scale, high-quality data is a resource-intensive and time-consuming endeavor. Compared to conventional Data Augmentation (DA) techniques (e.g. cropping and rotation), exploiting prevailing diffusion models for data…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yunxiang Fu , Chaoqi Chen , Yu Qiao , Yizhou Yu

The success of AI models relies on the availability of large, diverse, and high-quality datasets, which can be challenging to obtain due to data scarcity, privacy concerns, and high costs. Synthetic data has emerged as a promising solution…

Computation and Language · Computer Science 2024-08-13 Ruibo Liu , Jerry Wei , Fangyu Liu , Chenglei Si , Yanzhe Zhang , Jinmeng Rao , Steven Zheng , Daiyi Peng , Diyi Yang , Denny Zhou , Andrew M. Dai

Synthetic samples from diffusion models are promising for leveraging in training discriminative models as replications of real training datasets. However, we found that the synthetic datasets degrade classification performance over real…

Artificial Intelligence · Computer Science 2023-11-23 Shin'ya Yamaguchi , Takuma Fukuda

Individual health data is crucial for scientific advancements, particularly in developing Artificial Intelligence (AI); however, sharing real patient information is often restricted due to privacy concerns. A promising solution to this…

Detecting money laundering in gambling is becoming increasingly challenging for the gambling industry as consumers migrate to online channels. Whilst increasingly stringent regulations have been applied over the years to prevent money…

Machine Learning · Computer Science 2021-09-28 Charitos Charitou , Simo Dragicevic , Artur d'Avila Garcez

The usage of medical image data for the training of large-scale machine learning approaches is particularly challenging due to its scarce availability and the costly generation of data annotations, typically requiring the engagement of…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Joshua Niemeijer , Jan Ehrhardt , Hristina Uzunova , Heinz Handels

The widespread adoption of wearable sensors has the potential to provide massive and heterogeneous time series data, driving the use of Artificial Intelligence in human sensing applications. However, data collection remains limited due to…

Machine Learning · Computer Science 2025-12-04 Flavio Di Martino , Franca Delmastro

Predicting drug-gene associations is crucial for drug development and disease treatment. While graph neural networks (GNN) have shown effectiveness in this task, they face challenges with data sparsity and efficient contrastive learning…

Machine Learning · Computer Science 2025-02-14 Jiayang Wu , Wensheng Gan , Philip S. Yu