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We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem

Current 3D semi-supervised segmentation methods face significant challenges such as limited consideration of contextual information and the inability to generate reliable pseudo-labels for effective unsupervised data use. To address these…

Computer Vision and Pattern Recognition · Computer Science 2023-11-22 Sanaz Karimijafarbigloo , Reza Azad , Yury Velichko , Ulas Bagci , Dorit Merhof

The success of deep learning methods in medical image segmentation tasks heavily depends on a large amount of labeled data to supervise the training. On the other hand, the annotation of biomedical images requires domain knowledge and can…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Xinrong Hu , Dewen Zeng , Xiaowei Xu , Yiyu Shi

Reliable classification of benign and malignant lesions in breast ultrasound images can provide an effective and relatively low cost method for early diagnosis of breast cancer. The accuracy of the diagnosis is however highly dependent on…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Elham Yousef Kalaf , Ata Jodeiri , Seyed Kamaledin Setarehdan , Ng Wei Lin , Kartini Binti Rahman , Nur Aishah Taib , Sarinder Kaur Dhillon

Accurate and reliable histopathological image classification is essential for breast cancer diagnosis. However, many deep learning models remain sensitive to magnification variability and lack interpretability. To address these challenges,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Enam Ahmed Taufika , Md Ahasanul Arafatha , Abhijit Kumar Ghoshb , Md. Tanzim Rezab , Md Ashad Alamc

Convolutional neural networks can be trained to perform histology slide classification using weak annotations with multiple instance learning (MIL). However, given the paucity of labeled histology data, direct application of MIL can easily…

Computer Vision and Pattern Recognition · Computer Science 2019-11-05 Ming Y. Lu , Richard J. Chen , Jingwen Wang , Debora Dillon , Faisal Mahmood

Breast cancer is one of the leading causes of death for women worldwide. Early screening is essential for early identification, but the chance of survival declines as the cancer progresses into advanced stages. For this study, the most…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Fahad Ahmed , Reem Abdel-Salam , Leon Hamnett , Mary Adewunmi , Temitope Ayano

Self-supervised learning (SSL) has demonstrated its effectiveness in learning representations through comparison methods that align with human intuition. However, mainstream SSL methods heavily rely on high body datasets with single label,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Jiale Chen

Objective: We develop a computer-aided diagnosis (CAD) system using deep learning approaches for lesion detection and classification on whole-slide images (WSIs) with breast cancer. The deep features being distinguishing in classification…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Wei-Wen Hsu , Yongfang Wu , Chang Hao , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Tao He , Yanhong Tai

Deep neural networks have introduced significant advancements in the field of machine learning-based analysis of digital pathology images including prostate tissue images. With the help of transfer learning, classification and segmentation…

Building accurate and robust artificial intelligence systems for medical image assessment requires not only the research and design of advanced deep learning models but also the creation of large and curated sets of annotated training…

Computer Vision and Pattern Recognition · Computer Science 2022-01-05 Florin C. Ghesu , Bogdan Georgescu , Awais Mansoor , Youngjin Yoo , Dominik Neumann , Pragneshkumar Patel , R. S. Vishwanath , James M. Balter , Yue Cao , Sasa Grbic , Dorin Comaniciu

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

While machine learning is currently transforming the field of histopathology, the domain lacks a comprehensive evaluation of state-of-the-art models based on essential but complementary quality requirements beyond a mere classification…

Image and Video Processing · Electrical Eng. & Systems 2023-05-11 Maximilian Springenberg , Annika Frommholz , Markus Wenzel , Eva Weicken , Jackie Ma , Nils Strodthoff

Cancer is an extremely difficult and dangerous health problem because it manifests in so many different ways and affects so many different organs and tissues. The primary goal of this research was to evaluate deep learning models' ability…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 İrem Sayın , Muhammed Ali Soydaş , Yunus Emre Mert , Arda Yarkataş , Berk Ergun , Selma Sözen Yeh , Hüseyin Üvet

In Magnetic Resonance Imaging (MRI), image acquisitions are often undersampled in the measurement domain to accelerate the scanning process, at the expense of image quality. However, image quality is a crucial factor that influences the…

Image and Video Processing · Electrical Eng. & Systems 2024-05-31 Mevan Ekanayake , Zhifeng Chen , Mehrtash Harandi , Gary Egan , Zhaolin Chen

Tumour heterogeneity in breast cancer poses challenges in predicting outcome and response to therapy. Spatial transcriptomics technologies may address these challenges, as they provide a wealth of information about gene expression at the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Md Mamunur Rahaman , Ewan K. A. Millar , Erik Meijering

In computational pathology, we often face a scarcity of annotations and a large amount of unlabeled data. One method for dealing with this is semi-supervised learning which is commonly split into a self-supervised pretext task and a…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Manuel Tran , Sophia J. Wagner , Melanie Boxberg , Tingying Peng

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Abdulqader Mohammed , Mohammed Abdel Razek , Mohamed El-dosuky , Ahmed Sobhi

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

Contrastive learning applied to self-supervised representation learning has seen a resurgence in recent years, leading to state of the art performance in the unsupervised training of deep image models. Modern batch contrastive approaches…

Machine Learning · Computer Science 2021-03-12 Prannay Khosla , Piotr Teterwak , Chen Wang , Aaron Sarna , Yonglong Tian , Phillip Isola , Aaron Maschinot , Ce Liu , Dilip Krishnan