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We propose a probabilistic model for interpreting gene expression levels that are observed through single-cell RNA sequencing. In the model, each cell has a low-dimensional latent representation. Additional latent variables account for…

Machine Learning · Computer Science 2017-10-18 Romain Lopez , Jeffrey Regier , Michael Cole , Michael Jordan , Nir Yosef

Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

Neural and Evolutionary Computing · Computer Science 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay

Software vulnerabilities continue to undermine the reliability and security of modern systems, particularly as software complexity outpaces the capabilities of traditional detection methods. This study introduces a genetic algorithm-based…

Software Engineering · Computer Science 2025-08-11 Yanusha Mehendran , Maolin Tang , Yi Lu

Deep neural network-based architectures give promising results in various domains including pattern recognition. Finding the optimal combination of the hyper-parameters of such a large-sized architecture is tedious and requires a large…

Computer Vision and Pattern Recognition · Computer Science 2020-03-17 Animesh Singh , Sandip Saha , Ritesh Sarkhel , Mahantapas Kundu , Mita Nasipuri , Nibaran Das

We propose a genetic algorithm (GA) based method for modifying n-best lists produced by a machine translation (MT) system. Our method offers an innovative approach to improving MT quality and identifying weaknesses in evaluation metrics.…

Computation and Language · Computer Science 2023-06-01 Josef Jon , Ondřej Bojar

Feature selection has always been a critical step in pattern recognition, in which evolutionary algorithms, such as the genetic algorithm (GA), are most commonly used. However, the individual encoding scheme used in various GAs would either…

Machine Learning · Computer Science 2017-05-01 Benteng Ma , Yong Xia

Neural network models of real-world systems, such as industrial processes, made from sensor data must often rely on incomplete data. System states may not all be known, sensor data may be biased or noisy, and it is not often known which…

Neural and Evolutionary Computing · Computer Science 2007-06-08 Donald A. Sofge , David L. Elliott

Over the past twenty years, artificial Gene Regulatory Networks (GRNs) have shown their capacity to solve real-world problems in various domains such as agent control, signal processing and artificial life experiments. They have also…

Neural and Evolutionary Computing · Computer Science 2018-07-17 Dennis G Wilson , Kyle Harrington , Sylvain Cussat-Blanc , Hervé Luga

Due to the fast-growing volume of text documents and reviews in recent years, current analyzing techniques are not competent enough to meet the users' needs. Using feature selection techniques not only support to understand data better but…

Information Retrieval · Computer Science 2020-04-29 Amir Javadpour , Samira Rezaei , Kuan-Ching Li , Guojun Wang

Accelerating deep model training and inference is crucial in practice. Existing deep learning frameworks usually concentrate on optimizing training speed and pay fewer attentions to inference-specific optimizations. Actually, model…

Distributed, Parallel, and Cluster Computing · Computer Science 2020-08-12 Yongchao Liu , Yue Jin , Yong Chen , Teng Teng , Hang Ou , Rui Zhao , Yao Zhang

In this paper, we have to concentrate on implementation of Weighted Clustering Algorithm with the help of Genetic Algorithm (GA).Here we have developed new algorithm for the implementation of GA-based approach with the help of Weighted…

Networking and Internet Architecture · Computer Science 2010-02-11 Bhaskar Nandi , Subhabrata Barman , Soumen Paul

As machine learning (ML) is increasingly implemented in hardware to address real-time challenges in scientific applications, the development of advanced toolchains has significantly reduced the time required to iterate on various designs.…

Nowadays genetic algorithm (GA) is greatly used in engineering pedagogy as an adaptive technique to learn and solve complex problems and issues. It is a meta-heuristic approach that is used to solve hybrid computation challenges. GA…

Other Computer Science · Computer Science 2020-07-27 Tanweer Alam , Shamimul Qamar , Amit Dixit , Mohamed Benaida

This paper introduces warped Gaussian processes (WGP) regression in remote sensing applications. WGP models output observations as a parametric nonlinear transformation of a GP. The parameters of such prior model are then learned via…

Computer Vision and Pattern Recognition · Computer Science 2020-12-23 Anna Mateo-Sanchis , Jordi Muñoz-Marí , Adrián Pérez-Suay , Gustau Camps-Valls

Many statistical problems involve optimization over a discrete parameter space having an unknown dimension. In such settings, gradient-based methods often fail due to the non-differentiability of the objective function or a non-convex or…

Applications · Statistics 2026-03-19 Mo Li , QiQi Lu , Robert Lund , Xueheng Shi

Markov State Models (MSMs) are a powerful framework to reproduce the long-time conformational dynamics of biomolecules using a set of short Molecular Dynamics (MD) simulations. However, precise kinetics predictions of MSMs heavily rely on…

Biomolecules · Quantitative Biology 2018-06-27 Qihua Chen , Jiangyan Feng , Shriyaa Mittal , Diwakar Shukla

Semi-autogenous grinding (SAG) mills play a pivotal role in the grinding circuit of mineral processing plants. Accurate prediction of SAG mill throughput as a crucial performance metric is of utmost importance. The potential of applying…

Neural and Evolutionary Computing · Computer Science 2024-01-30 Zahra Ghasemi , Mehdi Nesht , Chris Aldrich , John Karageorgos , Max Zanin , Frank Neumann , Lei Chen

In recent years, machine learning has seen an increasing presencein a large variety of fields, especially in health care and bioinformatics.More specifically, the field where machine learning algorithms have found most applications is…

Neural and Evolutionary Computing · Computer Science 2020-08-21 Mekaal Swerhun , Jasmine Foley , Brandon Massop , Vijay Mago

The gene set analysis (GSA) is a foundational approach for uncovering the molecular functions associated with a group of genes. Recently, LLM-powered methods have emerged to annotate gene sets with biological functions together with…

Genomics · Quantitative Biology 2025-09-16 Zhizheng Wang , Yifan Yang , Qiao Jin , Zhiyong Lu

Advancements in AI have greatly enhanced the medical imaging process, making it quicker to diagnose patients. However, very few have investigated the optimization of a multi-model system with hardware acceleration. As specialized edge…

Hardware Architecture · Computer Science 2025-10-03 Ashiyana Abdul Majeed , Mahmoud Meribout , Safa Mohammed Sali