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At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

Neurons and Cognition · Quantitative Biology 2014-03-05 Mathieu Galtier , Jonathan Touboul

This paper introduces a class of stochastic models of interacting neurons with emergent dynamics similar to those seen in local cortical populations, and compares them to very simple reduced models driven by the same mean excitatory and…

Neurons and Cognition · Quantitative Biology 2017-11-07 Yao Li , Logan Chariker , Lai-Sang Young

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

A coupled map is suggested to investigate various spatial or temporal designs in biology: Several cells (or tissues) in an organ are considered as connected to each other in terms of some molecular diffusions or electrical potential…

General Physics · Physics 2011-06-07 Caglar Tuncay

Neural dynamics is determined by the transmission of discrete synaptic pulses (synaptic shot-noise) among neurons. However, the neural responses are usually obtained within the diffusion approximation modeling synaptic inputs as continuous…

Disordered Systems and Neural Networks · Physics 2025-10-17 Denis S. Goldobin , Maria V. Ageeva , Matteo di Volo , Ferdinand Tixidre , Alessandro Torcini

Modeling the neuronal processes underlying short-term working memory remains the focus of many theoretical studies in neuroscience. Here we propose a mathematical model of spiking neuron network (SNN) demonstrating how a piece of…

Neurons and Cognition · Quantitative Biology 2021-09-01 Yuliya Tsybina , Innokentiy Kastalskiy , Mikhail Krivonosov , Alexey Zaikin , Victor Kazantsev , Alexander Gorban , Susanna Gordleeva

We continue the work of a series of previous studies of a mathematical model that describes the mean-field limit behavior of a homogeneous network of excitatory point spiking neurons. Contrary to other models, here noise is intrinsic to the…

Neurons and Cognition · Quantitative Biology 2017-07-20 Guillem Via

In this article we present the modeling of bi-stability view problems described by the activity or firing rates of two interacting population of neurons. Starting from the study of a complex system, the sys-tem of stochastic differential…

Analysis of PDEs · Mathematics 2014-11-27 S Mancini

Neural mass models have been actively used since the 1970s to model the coarse grained activity of large populations of neurons and synapses. They have proven especially useful in understanding brain rhythms. However, although motivated by…

Neurons and Cognition · Quantitative Biology 2016-11-08 Stephen Coombes , Áine Byrne

We investigate different dynamical regimes of neuronal network in the CA3 area of the hippocampus. The proposed neuronal circuit includes two fast- and two slowly-spiking cells which are interconnected by means of dynamical synapses. On the…

Neurons and Cognition · Quantitative Biology 2015-11-20 Anastasia I. Lavrova , Michael A. Zaks , Lutz Schimansky-Geier

The participation of astrocytes in brain computation was formally hypothesized in 1992, coinciding with the discovery that these glial cells display a complex form of Ca2+ excitability. This fostered conceptual advances centered on the…

Neurons and Cognition · Quantitative Biology 2023-10-23 Ciaran Murphy-Royal , ShiNung Ching , Thomas Papouin

The brain can be understood as a collection of interacting neuronal oscillators, but the extent to which its sustained activity is due to coupling among brain areas is still unclear. Here we study the joint dynamics of two cortical columns…

Neurons and Cognition · Quantitative Biology 2018-01-17 Maciej Jedynak , Antonio J. Pons , Jordi Garcia-Ojalvo

An exact low-dimensional system of mean-field equations for an infinite-size network of pulse coupled integrate-and-fire neurons with a bimodal distribution of an excitability parameter is derived. Bifurcation analysis of these equations…

Chaotic Dynamics · Physics 2021-10-04 Viktoras Pyragas , Kestutis Pyragas

Firing rate fluctuations in neural populations are observed experimentally over multiple time scales, in single neurons, across trials when elicited by stimuli, and across populations. In this work, we examine how firing rate fluctuations…

Neurons and Cognition · Quantitative Biology 2026-05-15 Wilten Nicola , Sue Ann Campbell

Dynamical balance of excitation and inhibition is usually invoked to explain the irregular low firing activity observed in the cortex. We propose a robust nonlinear balancing mechanism for a random network of spiking neurons, which works…

Disordered Systems and Neural Networks · Physics 2025-05-29 Antonio Politi , Alessandro Torcini

Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, the…

Neurons and Cognition · Quantitative Biology 2015-05-05 Maurizio De Pittà , Nicolas Brunel , Andrea Volterra

We analyze the emergent regimes and the stimulus-response relationship of a population of noisy map neurons by means of a mean-field model, derived within the framework of cumulant approach complemented by the Gaussian closure hypothesis.…

Chaotic Dynamics · Physics 2017-09-13 Igor Franovic , Oleg V. Maslennikov , Iva Bacic , Vladimir I. Nekorkin

Neural oscillations are electrical activities of the brain measurable at different frequencies. This paper studies the interaction between the fast and slow processes in the brain. We recorded signals intracranially from the simple Wistar…

Neurons and Cognition · Quantitative Biology 2022-05-12 Evgeniia S. Sevasteeva , Sergei A. Plotnikov , Dmitry R. Belov

Strong inhibitory input to neurons, which occurs in balanced states of neural networks, increases synaptic current fluctuations. This has led to the assumption that inhibition contributes to the high spike-firing irregularity observed in…

Neurons and Cognition · Quantitative Biology 2021-02-19 Tomas Barta , Lubomir Kostal

The relation between spontaneous and stimulated brain activity is a fundamental question in neuroscience, which has received wide attention in experimental studies. Recently, it has been suggested that the evoked response to external…

Disordered Systems and Neural Networks · Physics 2023-06-16 M. K. Nandi , A. De Candia , A. Sarracino , H. J. Herrmann , L. de Arcangelis