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Mounting evidence in recent years suggests that astrocytes, a sub-type of glial cells, not only serve metabolic and structural support for neurons and synapses but also play critical roles in regulation of proper functioning of the nervous…

Neurons and Cognition · Quantitative Biology 2022-05-18 Tugba Palabas , Andre Longtin , Dibakar Ghosh , Muhammet Uzuntarla

The brain consists not only of neurons but also of non-neuronal cells, including astrocytes. Recent discoveries in neuroscience suggest that astrocytes directly regulate neuronal activity by releasing gliotransmitters such as glutamate. In…

Systems and Control · Electrical Eng. & Systems 2023-08-21 Valentin Würzbauer , Kerstin Lenk , Matin Jafarian

A mathematical model of a spiking neuron network accompanied by astrocytes is considered. The network is composed of excitatory and inhibitory neurons with synaptic connections supplied by a memristor-based model of plasticity. Another…

Neurons and Cognition · Quantitative Biology 2024-02-27 Sergey V. Stasenko , Alexey N. Mikhaylov , Alexander A. Fedotov , Vladimir A. Smirnov , Victor B. Kazantsev

Astrocytes are a ubiquitous and enigmatic type of non-neuronal cell and are found in the brain of all vertebrates. While traditionally viewed as being supportive of neurons, it is increasingly recognized that astrocytes may play a more…

Neurons and Cognition · Quantitative Biology 2023-11-13 Lulu Gong , Fabio Pasqualetti , Thomas Papouin , ShiNung Ching

Deciphering the complex interactions between neurotransmission and astrocytic $Ca^{2+}$ elevations is a target promising a comprehensive understanding of brain function. While the astrocytic response to excitatory synaptic activity has been…

Cell Behavior · Quantitative Biology 2019-03-19 Ioannis E. Polykretis , Vladimir A. Ivanov , Konstantinos P. Michmizos

Brain activities are featured by spatially distributed neural clusters of coherent firings and a spontaneous switching of the clusters between the synchrony and asynchrony states. Evidences from {\it in vivo} experiments suggest that…

Neurons and Cognition · Quantitative Biology 2023-02-02 Ya Wang , Liang Wang , Huawei Fan , Jun Ma , Hui Cao , Xingang Wang

Finding the origin of slow and infra-slow oscillations could reveal or explain brain mechanisms in health and disease. Here, we present a biophysically constrained computational model of a neural network where the inclusion of astrocytes…

Neurons and Cognition · Quantitative Biology 2017-02-15 Leo Kozachkov , Konstantinos P. Michmizos

The neuronal paradigm of studying the brain has left us with limitations in both our understanding of how neurons process information to achieve biological intelligence and how such knowledge may be translated into artificial intelligence…

Neurons and Cognition · Quantitative Biology 2020-05-12 Leo Kozachkov , Konstantinos P. Michmizos

The investigation of the neuronal environment allows us to better understand the activity of a cerebral region as a whole. The recent experimental evidences of the presence of transporters for glutamate and GABA in both neuronal and…

Neurons and Cognition · Quantitative Biology 2015-10-07 Aurélie Garnier , Alexandre Vidal , Habib Benali

A widely accepted view of computations in the brain relies on population coding, where the neural ensemble firing rate is modulated in a stable manner to transmit information and perform various cognitive tasks. At the same time,…

Neurons and Cognition · Quantitative Biology 2020-05-27 Nikita Novikov , Boris Gutkin

Collective oscillations and their suppression by external stimulation are analyzed in a large-scale neural network consisting of two interacting populations of excitatory and inhibitory quadratic integrate-and-fire neurons. In the limit of…

Neurons and Cognition · Quantitative Biology 2021-07-14 Kestutis Pyragas , Augustinas P. Fedaravičius , Tatjana Pyragienė

Understanding the role of astrocytes in brain computation is a nascent challenge, promising immense rewards, in terms of new neurobiological knowledge that can be translated into artificial intelligence. In our ongoing effort to identify…

Neurons and Cognition · Quantitative Biology 2018-07-10 Ioannis Polykretis , Vladimir Ivanov , Konstantinos P. Michmizos

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

Disordered Systems and Neural Networks · Physics 2020-03-11 Takashi Hayakawa , Tomoki Fukai

Astrocytes play a central role in inducing concerted phase synchronized neural-wave patterns inside the brain. In this article, we demonstrate that injected radio-frequency signal in underlying heavy metal layer of spin-orbit torque…

Emerging Technologies · Computer Science 2021-09-17 Umang Garg , Kezhou Yang , Abhronil Sengupta

We study a problem of designing ``robust'' external excitations for control and synchronization of an assembly of homotypic harmonic oscillators representing so-called theta neurons. The model of theta neurons (Theta model) captures, in…

Optimization and Control · Mathematics 2024-09-23 Roman Chertovskih , Nikolay Pogodaev , Maxim Staritsyn , Joaquim Da Silva Sewane , Antonio Pedro Aguiar

The dynamics of higher-order topological signals are increasingly recognized as a key aspect of the activity of complex systems. A paradigmatic example are synaptic dynamics: synaptic efficacy changes over time driven by different…

Neurons and Cognition · Quantitative Biology 2025-07-11 Gustavo Menesse , Ana P. Millán , Joaquín J. Torres

Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing…

Neurons and Cognition · Quantitative Biology 2011-12-06 Maurizio De Pittà , Vladislav Volman , Hugues Berry , Eshel Ben-Jacob

Traditional artificial neural networks take inspiration from biological networks, using layers of neuron-like nodes to pass information for processing. More realistic models include spiking in the neural network, capturing the electrical…

Machine Learning · Computer Science 2025-03-11 Christopher S. Yang , Sylvester J. Gates , Dulara De Zoysa , Jaehoon Choe , Wolfgang Losert , Corey B. Hart

Coherent activations of brain neuron networks underlay many physiological functions associated with various behavioral states. These synchronous fluctuations in the electrical activity of the brain are also referred to as brain rhythms. At…

Neurons and Cognition · Quantitative Biology 2023-12-07 Sergey V. Stasenko , Alexander E. Hramov , Victor B. Kazantsev

Neural coding is a key problem in neuroscience, which can promote people's understanding of the mechanism that brain processes information. Among the classical theories of neural coding, the population rate coding has been studied widely in…

Neurons and Cognition · Quantitative Biology 2019-08-13 Hao Si , Xiaojuan Sun
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