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In radiation therapy (RT) treatment planning, multi-criteria optimization (MCO) supports efficient plan selection but is usually solved for population-based dosimetric criteria and ignores patient-specific biological risk, potentially…

Medical Physics · Physics 2026-01-09 Mara Schubert , Katrin Teichert , Zhongxing Liao , Thomas Bortfeld , Ali Ajdari

A class of metaheuristic techniques called estimation-of-distribution algorithms (EDAs) are employed in optimization as more sophisticated substitutes for traditional strategies like evolutionary algorithms. EDAs generally drive the search…

Neural and Evolutionary Computing · Computer Science 2024-04-18 Sumit Adak , Carsten Witt

In the Markov paging model, one assumes that page requests are drawn from a Markov chain over the pages in memory, and the goal is to maintain a fast cache that suffers few page faults in expectation. While computing the optimal online…

Data Structures and Algorithms · Computer Science 2026-05-26 Chirag Pabbaraju , Ali Vakilian

We consider the problem of computing the value and an optimal strategy for minimizing the expected termination time in one-counter Markov decision processes. Since the value may be irrational and an optimal strategy may be rather…

Formal Languages and Automata Theory · Computer Science 2012-05-08 Tomáš Brázdil , Antonín Kučera , Petr Novotný , Dominik Wojtczak

Timetabling is a problem faced in all higher education institutions. The International Timetabling Competition (ITC) has published a dataset that can be used to test the quality of methods used to solve this problem. A number of…

Neural and Evolutionary Computing · Computer Science 2016-02-17 Patrick Kenekayoro , Godswill Zipamone

We consider leader election in clique networks, where $n$ nodes are connected by point-to-point communication links. For the synchronous clique under simultaneous wake-up, i.e., where all nodes start executing the algorithm in round $1$, we…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-09-27 Shay Kutten , Peter Robinson , Ming Ming Tan , Xianbin Zhu

We revisit the source coding problem for a Markov chain under the assumption that the transmission times and how fast the Markov chain transitions its state happen at the same time-scale. Specifically, we assume that the transmission of…

Information Theory · Computer Science 2025-11-05 Ismail Cosandal , Sennur Ulukus

Understanding how crossover works is still one of the big challenges in evolutionary computation research, and making our understanding precise and proven by mathematical means might be an even bigger one. As one of few examples where…

Neural and Evolutionary Computing · Computer Science 2015-06-22 Benjamin Doerr , Carola Doerr

The global simple evolutionary multi-objective optimizer (GSEMO) is a simple, yet often effective multi-objective evolutionary algorithm (MOEA). By only maintaining non-dominated solutions, it has a variable population size that…

Neural and Evolutionary Computing · Computer Science 2025-05-05 Benjamin Doerr , Martin Krejca , Andre Opris

We study algorithms to analyze a particular class of Markov population processes that is often used in epidemiology. More specifically, Markov binomial chains are the model that arises from stochastic time-discretizations of classical…

Logic in Computer Science · Computer Science 2025-06-25 Alejandro Alarcón Gonzalez , Niel Hens , Tim Leys , Guillermo A. Pérez

We analyse the problem of meeting times for interdependent stochastic agents: random walkers whose behaviour is stochastic but controlled by their selections from some set of allowed actions, and the inference problem of when these agents…

Probability · Mathematics 2025-10-10 Marco Sangalli , Erik Quaeghebeur , Thomas Krak

In modern logistics management systems, route planning requires high efficiency. The Open Capacitated Vehicle Routing Problem (OCVRP) deals with finding optimal delivery routes for a fleet of vehicles serving geographically distributed…

Computation and Language · Computer Science 2025-10-01 Assem Omar , Youssef Omar , Marwa Solayman , Hesham Mansour

Randomized search heuristics such as evolutionary algorithms, simulated annealing, and ant colony optimization are a broadly used class of general-purpose algorithms. Analyzing them via classical methods of theoretical computer science is a…

Neural and Evolutionary Computing · Computer Science 2015-03-18 Benjamin Doerr , Carola Winzen

Optimisation of fleets of commercial vehicles with regards scheduling tasks from various locations to vehicles can result in considerably lower fleet traversal times. This has significant benefits including reduced expenses for the company…

Neural and Evolutionary Computing · Computer Science 2019-04-17 Darren M. Chitty , Elizabeth Wanner , Rakhi Parmar , Peter R. Lewis

This paper illustrates successful implementation of three evolutionary algorithms, namely- Particle Swarm Optimization(PSO), Artificial Bee Colony (ABC) and Bacterial Foraging Optimization (BFO) algorithms to economic load dispatch problem…

Neural and Evolutionary Computing · Computer Science 2015-09-23 Anant Baijal , Vikram Singh Chauhan , T. Jayabarathi

We propose an active walker model for the motion of individual ants communicating via chemical signals. It is assumed that communication takes the form of a time-dependent pheromone field that feedbacks into the motion ants through…

Populations and Evolution · Quantitative Biology 2019-08-19 Jorge M Ramirez , Sara M Vallejo , Yurani Villa , Sara Gaona , Sarai Quintero

We study one-sided and $\alpha$-correct sequential hypothesis testing for data generated by an ergodic Markov chain. The null hypothesis is that the unknown transition matrix belongs to a prescribed set $P$ of stochastic matrices, and the…

Statistics Theory · Mathematics 2026-02-20 Alhad Sethi , Kavali Sofia Sagar , Shubhada Agrawal , Debabrota Basu , P. N. Karthik

We present a new method for proving lower bounds on the expected running time of evolutionary algorithms. It is based on fitness-level partitions and an additional condition on transition probabilities between fitness levels. The method is…

Neural and Evolutionary Computing · Computer Science 2015-03-19 Dirk Sudholt

Lead optimization in drug discovery requires efficiently navigating vast chemical space through iterative cycles to enhance molecular properties while preserving structural similarity to the original lead compound. Despite recent advances,…

Machine Learning · Computer Science 2025-09-29 Ziqing Wang , Yibo Wen , William Pattie , Xiao Luo , Weimin Wu , Jerry Yao-Chieh Hu , Abhishek Pandey , Han Liu , Kaize Ding

We consider the problem of learning the optimal action-value function in the discounted-reward Markov decision processes (MDPs). We prove a new PAC bound on the sample-complexity of model-based value iteration algorithm in the presence of…

Machine Learning · Computer Science 2012-07-03 Mohammad Gheshlaghi Azar , Remi Munos , Bert Kappen