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We consider a problem of data integration. Consider determining which genes affect a disease. The genes, which we call predictor objects, can be measured in different experiments on the same individual. We address the question of finding…

Machine Learning · Statistics 2016-10-04 Xin Gao , Raymond J. Carroll

In this work, the issue of Parkinson's disease (PD) diagnostics using non-invasive antemortem techniques was tackled. A deep learning approach for classification of raw speech recordings in patients with diagnosed PD was proposed. The core…

Computation and Language · Computer Science 2022-04-28 Maurycy Chronowski , Maciej Klaczynski , Malgorzata Dec-Cwiek , Karolina Porebska

There is a need of ensuring machine learning models that are interpretable. Higher interpretability of the model means easier comprehension and explanation of future predictions for end-users. Further, interpretable machine learning models…

Machine Learning · Computer Science 2020-08-17 Gregor Stiglic , Primoz Kocbek , Nino Fijacko , Marinka Zitnik , Katrien Verbert , Leona Cilar

With the rapid digitalization of healthcare systems, there has been a substantial increase in the generation and sharing of private health data. Safeguarding patient information is essential for maintaining consumer trust and ensuring…

Artificial Intelligence · Computer Science 2026-01-27 Yazan Otoum , Amiya Nayak

Modelling the progression of Degenerative Diseases (DD) is essential for detection, prevention, and treatment, yet it remains challenging due to the heterogeneity in disease trajectories among individuals. Factors such as demographics,…

Optimization and Control · Mathematics 2024-12-19 Alessandro Viani , Boris A Gutman , Emile d'Angremont , Marco Lorenzi

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-12-06 Cheng Zhang , Hedvig Kjellstrom , Bo C. Bertilson

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and…

Computation and Language · Computer Science 2024-10-08 Xueshen Li , Xinlong Hou , Nirupama Ravi , Ziyi Huang , Yu Gan

There is a growing interest in designing autonomous agents that can work alongside humans. Such agents will undoubtedly be expected to explain their behavior and decisions. While generating explanations is an actively researched topic, most…

Artificial Intelligence · Computer Science 2021-06-24 Utkarsh Soni , Sarath Sreedharan , Subbarao Kambhampati

Advances in precision medicine increasingly drive methodological innovation in health research. A key development is the use of personalized prediction models (PPMs), which are fit using a similar subpopulation tailored to a specific index…

Methodology · Statistics 2026-01-30 Tatiana Krikella , Joel A. Dubin

Elucidating the genetic basis of human diseases is a central goal of genetics and molecular biology. While traditional linkage analysis and modern high-throughput techniques often provide long lists of tens or hundreds of disease gene…

Quantitative Methods · Quantitative Biology 2011-06-03 Fantine Mordelet , Jean-Philippe Vert

In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical trials, we propose a…

In this work, we reflect on the data-driven modeling paradigm that is gaining ground in AI-driven automation of patient care. We argue that the repurposing of existing real-world patient datasets for machine learning may not always…

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

The issue of disagreements amongst human experts is a ubiquitous one in both machine learning and medicine. In medicine, this often corresponds to doctor disagreements on a patient diagnosis. In this work, we show that machine learning…

Machine Learning · Computer Science 2019-05-30 Maithra Raghu , Katy Blumer , Rory Sayres , Ziad Obermeyer , Robert Kleinberg , Sendhil Mullainathan , Jon Kleinberg

Blood biomarkers are an essential tool for healthcare providers to diagnose, monitor, and treat a wide range of medical conditions. Current reference values and recommended ranges often rely on population-level statistics, which may not…

Machine Learning · Computer Science 2024-07-11 A. Ali Heydari , Naghmeh Rezaei , Javier L. Prieto , Shwetak N. Patel , Ahmed A. Metwally

One of the goals of personalized medicine is to tailor diagnostics to individual patients. Diagnostics are performed in practice by measuring quantities, called biomarkers, that indicate the existence and progress of a disease. In common…

Medical Physics · Physics 2024-12-20 Diego Renner , Georgios Kissas

A method to identify probable diseases from the unstructured textual input (eg, health forum posts) by incorporating a lexicographic and semantic feature based two-phase text classification module and a symptom-disease correlation-based…

Information Retrieval · Computer Science 2024-09-05 Fahim Faisal , Shafkat Ahmed Bhuiyan , Abu Raihan Mostofa Kamal

Test data measured by medical instruments often carry imprecise ranges that include the true values. The latter are not obtainable in virtually all cases. Most learning algorithms, however, carry out arithmetical calculations that are…

Machine Learning · Computer Science 2020-07-27 Mei Wang , Jianwen Su , Haiqin Lu

This manuscript presents a methodical examination of the utilization of Artificial Intelligence in the assessment of emotions in texts related to healthcare, with a particular focus on the incorporation of Natural Language Processing and…

Computation and Language · Computer Science 2024-04-22 Prashant Kumar Nag , Amit Bhagat , R. Vishnu Priya , Deepak kumar Khare

Temporal context in medicine is valuable in assessing key changes in patient health over time. We developed a machine learning framework to integrate diverse context from prior visits to improve health monitoring, especially when prior…

Artificial Intelligence · Computer Science 2025-10-20 Lavanya Umapathy , Patricia M Johnson , Tarun Dutt , Angela Tong , Madhur Nayan , Hersh Chandarana , Daniel K Sodickson