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The theory of optimal transportation has developed into a powerful and elegant framework for comparing probability distributions, with wide-ranging applications in all areas of science. The fundamental idea of analyzing probabilities by…

Methodology · Statistics 2025-03-14 Florian F Gunsilius

Consciousness spans macroscopic experience and microscopic neuronal activity, yet linking these scales remains challenging. Prevailing theories, such as Integrated Information Theory, focus on a single scale, overlooking how causal power…

Neurons and Cognition · Quantitative Biology 2025-09-16 Zhipeng Wang , Yingqi Rong , Kaiwei Liu , Mingzhe Yang , Jiang Zhang , Jing He

Higher educational institutions constantly look for ways to meet students' needs and support them through graduation. Recent work in the field of learning analytics have developed methods for grade prediction and course recommendations.…

Applications · Statistics 2019-06-12 Prableen Kaur , Agoritsa Polyzou , George Karypis

Repeated occurrences of serial firing sequences of a group of neurons with fixed time delays between neurons are observed in many experiments involving simultaneous recordings from multiple neurons. Such temporal patterns are potentially…

Neurons and Cognition · Quantitative Biology 2008-09-01 C. O. Diekman , P. S. Sastry , K. P. Unnikrishnan

Recent technological advances have made it possible to simultaneously measure multiple protein activities at the single cell level. With such data collected under different stimulatory or inhibitory conditions, it is possible to infer the…

Applications · Statistics 2011-08-04 Ruiyan Luo , Hongyu Zhao

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

This paper examines methods of causal inference based on groupwise matching when we observe multiple large groups of individuals over several periods. We formulate causal inference validity through a generalized matching condition,…

Econometrics · Economics 2026-03-24 Ratzanyel Rincón , Kyungchul Song

Inference of causality is central in nonlinear time series analysis and science in general. A popular approach to infer causality between two processes is to measure the information flow between them in terms of transfer entropy. Using…

Chaotic Dynamics · Physics 2015-04-16 Jie Sun , Erik M. Bollt

Understanding how stimuli and synaptic connectivity in uence the statistics of spike patterns in neural networks is a central question in computational neuroscience. Maximum Entropy approach has been successfully used to characterize the…

Biological Physics · Physics 2016-11-26 Rodrigo Cofre , Bruno Cessac

Optogenetics is a powerful neuroscience technique for studying how neural circuit manipulation affects behavior. Standard analysis conventions discard information and severely limit the scope of the causal questions that can be probed. To…

Methodology · Statistics 2025-07-02 Gabriel Loewinger , Alexander W. Levis , Francisco Pereira

Deep neural networks are increasingly utilized in mobility prediction tasks, yet their intricate internal workings pose challenges for interpretability, especially in comprehending how various aspects of mobility behavior affect…

Physics and Society · Physics 2024-08-02 Ye Hong , Yanan Xin , Simon Dirmeier , Fernando Perez-Cruz , Martin Raubal

Causal inference is a fundamental research topic for discovering the cause-effect relationships in many disciplines. However, not all algorithms are equally well-suited for a given dataset. For instance, some approaches may only be able to…

Machine Learning · Computer Science 2024-03-11 Zhipeng Ma , Marco Kemmerling , Daniel Buschmann , Chrismarie Enslin , Daniel Lütticke , Robert H. Schmitt

A single neuron is known to generate almost identical spike trains when the same fluctuating input is repeatedly applied. Here, we study the reliability of spike firing in a pulse-coupled network of oscillator neurons receiving fluctuating…

Adaptation and Self-Organizing Systems · Physics 2015-05-13 Jun-nosuke Teramae , Tomoki Fukai

Causality plays a central role in understanding interactions between variables in complex systems. These systems often exhibit state-dependent causal relationships, where both the strength and direction of causality vary with the value of…

Data Analysis, Statistics and Probability · Physics 2025-08-05 Álvaro Martínez-Sánchez , Adrián Lozano-Durán

Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jorge F. Mejias , Joaquin J. Torres

After coarse-graining a complex system, the dynamics of its macro-state may exhibit more pronounced causal effects than those of its micro-state. This phenomenon, known as causal emergence, is quantified by the indicator of effective…

Information Theory · Computer Science 2025-02-13 Kaiwei Liu , Bing Yuan , Jiang Zhang

Multi-task learning is frequently used to model a set of related response variables from the same set of features, improving predictive performance and modeling accuracy relative to methods that handle each response variable separately.…

Methodology · Statistics 2023-08-11 Snigdha Panigrahi , Natasha Stewart , Chandra Sekhar Sripada , Elizaveta Levina

Bipartite experiments arise in various fields, in which the treatments are randomized over one set of units, while the outcomes are measured over another separate set of units. However, existing methods often rely on strong model…

Methodology · Statistics 2025-04-16 Sizhu Lu , Lei Shi , Yue Fang , Wenxin Zhang , Peng Ding

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have…

Neurons and Cognition · Quantitative Biology 2018-02-07 Andrea K. Barreiro , Shree Hari Gautam , Woodrow L. Shew , Cheng Ly

The research questions that motivate transportation safety studies are causal in nature. Safety researchers typically use observational data to answer such questions, but often without appropriate causal inference methodology. The field of…

Applications · Statistics 2011-07-26 Vishesh Karwa , Aleksandra B. Slavković , Eric T. Donnell
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