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Related papers: Boosting 3D Neuron Segmentation with 2D Vision Tra…

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Reconstructing neuron morphology from 3D light microscope imaging data is critical to aid neuroscientists in analyzing brain networks and neuroanatomy. With the boost from deep learning techniques, a variety of learning-based segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-02-18 Yik San Cheng , Runkai Zhao , Heng Wang , Hanchuan Peng , Yui Lo , Yuqian Chen , Lauren J. O'Donnell , Weidong Cai

Automatic 3D neuron reconstruction is critical for analysing the morphology and functionality of neurons in brain circuit activities. However, the performance of existing tracing algorithms is hinged by the low image quality. Recently, a…

Image and Video Processing · Electrical Eng. & Systems 2021-09-17 Heng Wang , Chaoyi Zhang , Jianhui Yu , Yang Song , Siqi Liu , Wojciech Chrzanowski , Weidong Cai

Given the prevalence of 3D medical imaging technologies such as MRI and CT that are widely used in diagnosing and treating diverse diseases, 3D segmentation is one of the fundamental tasks of medical image analysis. Recently,…

Computer Vision and Pattern Recognition · Computer Science 2023-02-10 Yuhui Zhang , Shih-Cheng Huang , Zhengping Zhou , Matthew P. Lungren , Serena Yeung

Digital neuron reconstruction from 3D microscopy images is an essential technique for investigating brain connectomics and neuron morphology. Existing reconstruction frameworks use convolution-based segmentation networks to partition the…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Runkai Zhao , Heng Wang , Chaoyi Zhang , Weidong Cai

Motivation: 3D neuron segmentation is a key step for the neuron digital reconstruction, which is essential for exploring brain circuits and understanding brain functions. However, the fine line-shaped nerve fibers of neuron could spread in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-09 Qiufu Li , Linlin Shen

Background Analyzing images to accurately estimate the number of different cell types in the brain using automatic methods is a major objective in neuroscience. The automatic and selective detection and segmentation of neurons would be an…

Image and Video Processing · Electrical Eng. & Systems 2024-10-07 Antonio LaTorre , Lidia Alonso-Nanclares , José María Peña , Javier De Felipe

Semantic segmentation of neuronal structures in 3D high-resolution fluorescence microscopy imaging of the human brain cortex can take advantage of bidimensional CNNs, which yield good results in neuron localization but lead to inaccurate…

Image and Video Processing · Electrical Eng. & Systems 2020-09-03 Filippo Maria Castelli , Matteo Roffilli , Giacomo Mazzamuto , Irene Costantini , Ludovico Silvestri , Francesco Saverio Pavone

The neuron reconstruction from raw Optical Microscopy (OM) image stacks is the basis of neuroscience. Manual annotation and semi-automatic neuron tracing algorithms are time-consuming and inefficient. Existing deep learning neuron…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Yijun Wang , Rui Lang , Rui Li , Junsong Zhang

Automated sample preparation and electron microscopy enables acquisition of very large image data sets. These technical advances are of special importance to the field of neuroanatomy, as 3D reconstructions of neuronal processes at the nm…

The difficulties in both data acquisition and annotation substantially restrict the sample sizes of training datasets for 3D medical imaging applications. As a result, constructing high-performance 3D convolutional neural networks from…

Image and Video Processing · Electrical Eng. & Systems 2022-01-06 Shu Zhang , Zihao Li , Hong-Yu Zhou , Jiechao Ma , Yizhou Yu

Neuron reconstruction is essential to generate exquisite neuron connectivity map for understanding brain function. Despite the significant amount of effect that has been made on automatic reconstruction methods, manual tracing by…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Donghuan Lu , Sujun Zhao , Peng Xie , Kai Ma , Lijuan Liu , Yefeng Zheng

Convolutional neural networks are state-of-the-art for various segmentation tasks. While for 2D images these networks are also computationally efficient, 3D convolutions have huge storage requirements and therefore, end-to-end training is…

Computer Vision and Pattern Recognition · Computer Science 2022-02-01 Christoph Angermann , Markus Haltmeier

One of the critical steps in improving accurate single neuron reconstruction from three-dimensional (3D) optical microscope images is the neuronal structure segmentation. However, they are always hard to segment due to the lack in quality.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-25 Heng Wang , Yang Song , Chaoyi Zhang , Jianhui Yu , Siqi Liu , Hanchuan Peng , Weidong Cai

Neuroimaging to neuropathology correlation (NTNC) promises to enable the transfer of microscopic signatures of pathology to in vivo imaging with MRI, ultimately enhancing clinical care. NTNC traditionally requires a volumetric MRI scan,…

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

Like other applications in computer vision, medical image segmentation has been most successfully addressed using deep learning models that rely on the convolution operation as their main building block. Convolutions enjoy important…

Image and Video Processing · Electrical Eng. & Systems 2022-04-05 Davood Karimi , Serge Vasylechko , Ali Gholipour

3D image segmentation plays an important role in biomedical image analysis. Many 2D and 3D deep learning models have achieved state-of-the-art segmentation performance on 3D biomedical image datasets. Yet, 2D and 3D models have their own…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Hao Zheng , Yizhe Zhang , Lin Yang , Peixian Liang , Zhuo Zhao , Chaoli Wang , Danny Z. Chen

Convolutional neural networks are state-of-the-art for various segmentation tasks. While for 2D images these networks are also computationally efficient, 3D convolutions have huge storage requirements and require long training time. To…

Computer Vision and Pattern Recognition · Computer Science 2019-08-06 Christoph Angermann , Markus Haltmeier , Ruth Steiger , Sergiy Pereverzyev , Elke Gizewski

Deep convolutional neural networks (CNNs) are state-of-the-art for semantic image segmentation, but typically require many labeled training samples. Obtaining 3D segmentations of medical images for supervised training is difficult and labor…

Computer Vision and Pattern Recognition · Computer Science 2019-07-29 Zhenlin Xu , Marc Niethammer

2D visual foundation models, such as DINOv3, a self-supervised model trained on large-scale natural images, have demonstrated strong zero-shot generalization, capturing both rich global context and fine-grained structural cues. However, an…

Computer Vision and Pattern Recognition · Computer Science 2026-03-25 Yik San Cheng , Runkai Zhao , Weidong Cai
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