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Physics-informed neural networks (PINNs) [31] use automatic differentiation to solve partial differential equations (PDEs) by penalizing the PDE in the loss function at a random set of points in the domain of interest. Here, we develop a…

Neural and Evolutionary Computing · Computer Science 2019-12-03 E. Kharazmi , Z. Zhang , G. E. Karniadakis

Systems biology and systems neurophysiology in particular have recently emerged as powerful tools for a number of key applications in the biomedical sciences. Nevertheless, such models are often based on complex combinations of multiscale…

Neural and Evolutionary Computing · Computer Science 2022-09-27 Matteo Ferrante , Andera Duggento , Nicola Toschi

Physics-informed neural networks (PINNs) solve time-dependent partial differential equations (PDEs) by learning a mesh-free, differentiable solution that can be evaluated anywhere in space and time. However, standard space--time PINNs take…

Machine Learning · Computer Science 2026-01-29 Chen-Yang Dai , Che-Chia Chang , Te-Sheng Lin , Ming-Chih Lai , Chieh-Hsin Lai

For multi-scale problems, the conventional physics-informed neural networks (PINNs) face some challenges in obtaining available predictions. In this paper, based on PINNs, we propose a practical deep learning framework for multi-scale…

Machine Learning · Computer Science 2024-12-18 Yong Wang , Yanzhong Yao , Jiawei Guo , Zhiming Gao

Physics-informed neural networks (PINNs) have gained significant prominence as a powerful tool in the field of scientific computing and simulations. Their ability to seamlessly integrate physical principles into deep learning architectures…

Machine Learning · Computer Science 2024-04-05 Zakaria Elabid , Daniel Busby , Abdenour Hadid

Physics-informed neural networks (PINNs) have been popularized as a deep learning framework that can seamlessly synthesize observational data and partial differential equation (PDE) constraints. Their practical effectiveness however can be…

Machine Learning · Computer Science 2023-08-17 Sifan Wang , Shyam Sankaran , Hanwen Wang , Paris Perdikaris

Physics informed neural networks approximate solutions of PDEs by minimizing pointwise residuals. We derive rigorous bounds on the error, incurred by PINNs in approximating the solutions of a large class of linear parabolic PDEs, namely…

Numerical Analysis · Mathematics 2021-07-13 Tim De Ryck , Siddhartha Mishra

Physics-Informed Neural Networks (PINNs) offer a promising approach to solving differential equations and, more generally, to applying deep learning to problems in the physical sciences. We adopt a recently developed transfer learning…

Machine Learning · Computer Science 2022-11-02 Raphaël Pellegrin , Blake Bullwinkel , Marios Mattheakis , Pavlos Protopapas

Physics-informed neural networks (PINNs) have emerged as a versatile and widely applicable concept across various science and engineering domains over the past decade. This article offers a comprehensive overview of the fundamentals of…

Computational Engineering, Finance, and Science · Computer Science 2024-10-02 Sai Ganga , Ziya Uddin

Physics-informed neural networks (PINNs) are an increasingly powerful way to solve partial differential equations, generate digital twins, and create neural surrogates of physical models. In this manuscript we detail the inner workings of…

Learning the solution of partial differential equations (PDEs) with a neural network is an attractive alternative to traditional solvers due to its elegance, greater flexibility and the ease of incorporating observed data. However, training…

Machine Learning · Computer Science 2024-07-18 Katsiaryna Haitsiukevich , Alexander Ilin

In this paper, we study physics-informed neural networks (PINN) to approximate solutions to one-dimensional boundary value problems for linear elliptic equations and establish robust error estimates of PINN regardless of the quantities of…

Numerical Analysis · Mathematics 2024-09-06 Jihahm Yoo , Haesung Lee

Physics-Informed Neural Networks (PINNs) solve partial differential equations using deep learning. However, conventional PINNs perform pointwise predictions that neglect dependencies within a domain, which may result in suboptimal…

Machine Learning · Computer Science 2025-05-26 Mayank Nagda , Phil Ostheimer , Thomas Specht , Frank Rhein , Fabian Jirasek , Stephan Mandt , Marius Kloft , Sophie Fellenz

Physics-Informed Neural Networks (PINNs) encounter accuracy limitations when solving the Allen--Cahn (AC) and Cahn--Hilliard (CH) partial differential equations (PDEs). To overcome this, we employ a novel loss function, Residuals-weighted…

Numerical Analysis · Mathematics 2026-02-25 Guangtao Zhang , Jiani Lin , Qijia Zhai , Huiyu Yang , Xujun Chen , Ieng Tak Leong , Fang Zhu

Solving the two-dimensional shallow water equations is a fundamental problem in flood simulation technology. In recent years, physics-informed neural networks (PINNs) have emerged as a novel methodology for addressing this problem. Given…

Fluid Dynamics · Physics 2025-01-22 Yongfu Tian , Shan Ding , Guofeng Su , Lida Huang , Jianguo Chen

Physics informed neural networks (PINNs) are deep learning based techniques for solving partial differential equations (PDEs) encounted in computational science and engineering. Guided by data and physical laws, PINNs find a neural network…

Numerical Analysis · Mathematics 2020-12-30 Yeonjong Shin , Jerome Darbon , George Em Karniadakis

Physics-Informed Neural Networks (PINNs) have been recognized as a mesh-free alternative to solve partial differential equations where physics information is incorporated. However, in dealing with problems characterized by high stiffness or…

Machine Learning · Computer Science 2026-03-04 Divyavardhan Singh , Shubham Kamble , Dimple Sonone , Kishor Upla

Physics-Informed Neural Networks (PINNs) are a novel computational approach for solving partial differential equations (PDEs) with noisy and sparse initial and boundary data. Although, efficient quantification of epistemic and aleatoric…

Machine Learning · Computer Science 2025-05-02 Júlia Vicens Figueres , Juliette Vanderhaeghen , Federica Bragone , Kateryna Morozovska , Khemraj Shukla

A physics-informed neural network (PINN) uses physics-augmented loss functions, e.g., incorporating the residual term from governing partial differential equations (PDEs), to ensure its output is consistent with fundamental physics laws.…

Machine Learning · Computer Science 2022-12-16 Jian Cheng Wong , Chinchun Ooi , Abhishek Gupta , Yew-Soon Ong

Since the introduction of deep learning for solving partial differential equations (PDEs), there has been growing interest in real-time system responses, where the kernel function plays a key role. Physics-informed neural networks (PINNs),…

Numerical Analysis · Mathematics 2025-11-17 Xiaopei Jiao , Fansheng Xiong