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High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

High-performance computing (HPC) has evolved over decades through multiple architectural transitions, from vector supercomputers to massively parallel CPU clusters and GPU-accelerated systems, continuously expanding the frontier of…

Quantum Physics · Physics 2026-04-23 Suman Raj , Siva Sai , Yogesh Simmhan , Kyle Chard , Rajkumar Buyya

We conducted a systematic survey of emerging quantum-HPC platforms, which integrate quantum computers and High-Performance Computing (HPC) systems through co-location. Currently, it remains unclear whether such platforms provide tangible…

The increasing capabilities of Machine Learning (ML) models go hand in hand with an immense amount of data and computational power required for training. Therefore, training is usually outsourced into HPC facilities, where we have started…

Machine Learning · Computer Science 2025-01-28 Sabrina Herbst , Vincenzo De Maio , Ivona Brandic

Training and Hyperparameter Optimization (HPO) of deep learning-based AI models are often compute resource intensive and calls for the use of large-scale distributed resources as well as scalable and resource efficient hyperparameter search…

Data Analysis, Statistics and Probability · Physics 2023-03-28 Eric Wulff , Maria Girone , David Southwick , Juan Pablo García Amboage , Eduard Cuba

The use of quantum processing units (QPUs) promises speed-ups for solving computational problems, but the quantum devices currently available possess only a very limited number of qubits and suffer from considerable imperfections. One…

Hardware Architecture · Computer Science 2022-09-26 Karen Wintersperger , Hila Safi , Wolfgang Mauerer

The prospects of quantum computing have driven efforts to realize fully functional quantum processing units (QPUs). Recent success in developing proof-of-principle QPUs has prompted the question of how to integrate these emerging processors…

Emerging Technologies · Computer Science 2015-12-10 Keith A. Britt , Travis S. Humble

While modern parallel computing systems offer high performance, utilizing these powerful computing resources to the highest possible extent demands advanced knowledge of various hardware architectures and parallel programming models.…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-05-03 Suejb Memeti , Sabri Pllana , Alecio Binotto , Joanna Kolodziej , Ivona Brandic

As quantum computers continue to improve and support larger, more complex computations, smart control hardware and compilers are needed to efficiently leverage the capabilities of these systems. This paper introduces a novel approach to…

Quantum Physics · Physics 2025-11-19 Folkert de Ronde , Alexander Knapen , Stephan Wong , Sebastian Feld

This paper presents a systematic review of mapping and scheduling strategies within the High-Performance Computing (HPC) compute continuum, with a particular emphasis on heterogeneous systems. It introduces a prototype workflow to establish…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-19 Aasish Kumar Sharma , Julian Kunkel

Quantum computing promises potential for science and industry by solving certain computationally complex problems faster than classical computers. Quantum computing systems evolved from monolithic systems towards modular architectures…

Quantum Physics · Physics 2023-08-15 Nishant Saurabh , Shantenu Jha , Andre Luckow

This paper explores the use of optimization to design multifunctional metamaterials, and proposes a methodology for constructing a design envelope of potential properties. A thermal-mechanical metamaterial, proposed by Ai and Gao (2017), is…

Computational Engineering, Finance, and Science · Computer Science 2020-04-29 Ewan Fong , Sadik L. Omairey , Peter D. Dunning

In this paper, we propose the first optimum process scheduling algorithm for an increasingly prevalent type of heterogeneous multicore (HEMC) system that combines high-performance big cores and energy-efficient small cores with the same…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-09-13 Chien-Hao Chen , Ren-Song Tsay

Model Predictive Control (MPC) is a computationally demanding control technique that allows dealing with multiple-input and multiple-output systems, while handling constraints in a systematic way. The necessity of solving an optimization…

Systems and Control · Computer Science 2021-12-16 Bulat Khusainov , Eric C. Kerrigan , George A. Constantinides

In the expanding field of Quantum Computing (QC), efficient and seamless integration of QC and high performance computing (HPC) elements (e.g., quantum hardware, classical hardware, and software infrastructure on both sides) plays a crucial…

Quantum Physics · Physics 2023-09-08 Philipp Seitz , Amr Elsharkawy , Xiao-Ting Michelle To , Martin Schulz

Practical applicability of quantum optimisation on near term devices is constrained by limited qubit counts and hardware noise, which restricts the scalability of quantum optimisation algorithms for combinatorial problems. The simulation of…

Quantum Physics · Physics 2026-05-01 Namasi G Sankar , Georgios Miliotis , Simon Caton

Classical optimization algorithms in machine learning often take a long time to compute when applied to a multi-dimensional problem and require a huge amount of CPU and GPU resource. Quantum parallelism has a potential to speed up machine…

Quantum Physics · Physics 2019-11-21 Venkat R. Dasari , Mee Seong Im , Lubjana Beshaj

Simulating the time evolution of a physical system at quantum mechanical levels of detail -- known as Hamiltonian Simulation (HS) -- is an important and interesting problem across physics and chemistry. For this task, algorithms that run on…

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