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Designing novel proteins with desired functions is crucial in biology and chemistry. However, most existing work focus on protein sequence design, leaving protein sequence and structure co-design underexplored. In this paper, we propose…

Machine Learning · Computer Science 2023-10-05 Zhenqiao Song , Yunlong Zhao , Yufei Song , Wenxian Shi , Yang Yang , Lei Li

Computing has revolutionized the biological sciences over the past several decades, such that virtually all contemporary research in the biosciences utilizes computer programs. The computational advances have come on many fronts, spurred by…

Other Quantitative Biology · Quantitative Biology 2021-08-23 Berk Ekmekci , Charles E. McAnany , Cameron Mura

We present pyroomacoustics, a software package aimed at the rapid development and testing of audio array processing algorithms. The content of the package can be divided into three main components: an intuitive Python object-oriented…

Sound · Computer Science 2019-05-08 Robin Scheibler , Eric Bezzam , Ivan Dokmanić

Today, artificial intelligence systems driven by machine learning algorithms can be in a position to take important, and sometimes legally binding, decisions about our everyday lives. In many cases, however, these systems and their actions…

Machine Learning · Computer Science 2022-08-26 Kacper Sokol , Raul Santos-Rodriguez , Peter Flach

The RooUnfold package provides a common framework to evaluate and use different unfolding algorithms, side-by-side. It currently provides implementations or interfaces for the Iterative Bayes, Singular Value Decomposition, and TUnfold…

Data Analysis, Statistics and Probability · Physics 2011-12-09 Tim Adye

We present a novel coupled two-way clustering approach to gene microarray data analysis. The main idea is to identify subsets of the genes and samples, such that when one of these is used to cluster the other, stable and significant…

Biological Physics · Physics 2009-11-06 G. Getz , E. Levine , E. Domany

Behavioral studies using personal digital devices typically produce rich longitudinal datasets of mixed data types. These data provide information about the behavior of users of these devices in real-time and in the users' natural…

Human-Computer Interaction · Computer Science 2022-12-06 A. Ikäheimonen , A. M. Triana , N. Luong , A. Ziaei , J. Rantaharju , R. Darst , T. Aledavood

The open-source PyNX toolkit [Favre-Nicolin et al (2011) arXiv:1010.2641, Mandula et al (2016)] has been extended to provide tools for coherent X-ray imaging data analysis and simulation. All calculations can be executed on graphical…

We introduce milearn, a Python package for multi-instance learning (MIL) that follows the familiar scikit-learn fit/predict interface while providing a unified framework for both classical and neural-network-based MIL algorithms for…

Machine Learning · Computer Science 2025-12-02 Dmitry Zankov , Pavlo Polishchuk , Michal Sobieraj , Mario Barbatti

Background. In modern software development, the use of external libraries and packages is increasingly prevalent, streamlining the software development process and enabling developers to deploy feature-rich systems with little coding. While…

Software Engineering · Computer Science 2024-12-09 Haya Samaana , Diego Elias Costa , Emad Shihab , Ahmad Abdellatif

Proteins are biomolecules of life. They fold into a great variety of three-dimensional (3D) shapes. Underlying these folding patterns are many recurrent structural fragments or building blocks (analogous to `LEGO bricks'). This paper…

Quantitative Methods · Quantitative Biology 2013-10-08 Arun S. Konagurthu , Arthur M. Lesk , David Abramson , Peter J. Stuckey , Lloyd Allison

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

The increased computational and experimental interest in perovskite systems comprising novel phases and reduced dimensionality has greatly expanded the search space for this class of materials. In similar fields, unified frameworks exist…

Materials Science · Physics 2023-08-31 Robert Stanton , Dhara J. Trivedi

This paper introduces a new Python package specifically designed to address calibration of probabilistic classifiers under dataset shift. The method is demonstrated in binary and multi-class settings and its effectiveness is measured…

Machine Learning · Computer Science 2025-09-16 Ivan Petej

In today's modern wide-field galaxy surveys, there is the necessity for parametric surface brightness decomposition codes characterised by accuracy, small degree of user intervention, and high degree of parallelisation. We try to address…

Astrophysics of Galaxies · Physics 2023-03-03 Luca Tortorelli , Amata Mercurio

We present here the first release of the open-source python package ExoTETHyS, which aims to provide a stand-alone set of tools for modeling spectro-photometric observations of the transiting exoplanets. In particular, we describe: (1) a…

Earth and Planetary Astrophysics · Physics 2020-02-05 Giuseppe Morello , Antonio Claret , Marine Martin-Lagarde , Christophe Cossou , Angelos Tsiaras , Pierre-Olivier Lagage

Converting peptide sequences into useful representations for downstream analysis is a common step in computational modeling and cheminformatics. Furthermore, peptide drugs (e.g., Semaglutide, Degarelix) often take advantage of the diverse…

Biomolecules · Quantitative Biology 2025-05-05 Aaron L. Feller , Claus O. Wilke

Motivation: ``Molecular signatures'' or ``gene-expression signatures'' are used to predict patients' characteristics using data from coexpressed genes. Signatures can enhance understanding about biological mechanisms and have diagnostic…

Quantitative Methods · Quantitative Biology 2007-05-23 Ramon Diaz-Uriarte

The emission lines from ionized nebulae allow us to determine their physical and chemical properties, along with the interstellar extinction. "pyEQUIB" is a pure Python open-source package including several application programming interface…

Instrumentation and Methods for Astrophysics · Physics 2024-11-25 A. Danehkar

This paper presents a new modeling strategy for joint unsupervised analysis of multiple high-throughput biological studies. As in Multi-study Factor Analysis, our goals are to identify both common factors shared across studies and…

Applications · Statistics 2018-06-27 Roberta De Vito , Ruggero Bellio , Lorenzo Trippa , Giovanni Parmigiani
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