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The long-time behavior of many complex molecular systems is often governed by slow relaxation dynamics that can be described by a few reaction coordinates referred to as collective variables (CVs). However, identifying CVs hidden in a…

Chemical Physics · Physics 2024-09-26 Jakub Rydzewski , Tuğçe Gökdemir

The coordinated and efficient distribution of limited resources by individual decisions is a fundamental, unsolved problem. When individuals compete for road capacities, time, space, money, goods, etc., they normally make decisions based on…

Statistical Mechanics · Physics 2009-11-07 Dirk Helbing , Martin Schoenhof , Daniel Kern

In this work, we investigate the optimal control problem for continuous-time Markov decision processes with the random impact of the environment. We provide conditions to show the existence of optimal controls under finite-horizon criteria.…

Optimization and Control · Mathematics 2020-06-23 Jinghai Shao , Kun Zhao

We study the selection of covariate adjustment sets for estimating the value of point exposure dynamic policies, also known as dynamic treatment regimes, assuming a non-parametric causal graphical model with hidden variables, in which at…

Statistics Theory · Mathematics 2020-05-27 Ezequiel Smucler , Facundo Sapienza , Andrea Rotnitzky

Quantum systems coupled to environments exhibit intricate dynamics. The master equation gives a Markov approximation of the dynamics, allowing for analytic and numerical treatments. It is ubiquitous in theoretical and applied quantum…

Quantum Physics · Physics 2021-12-17 Marco Merkli

We study a class of stochastic exchangeable teams with a finite number of decision makers (DMs) as well as their mean-field limits with infinitely many DMs. In the finite population regime, we study exchangeable teams under the centralized…

Optimization and Control · Mathematics 2025-08-26 Sina Sanjari , Naci Saldi , Serdar Yüksel

This paper is devoted to distributed continuous-time and discrete-time optimization problems with nonuniform convex constraint sets and nonuniform stepsizes for general differentiable convex objective functions. The communication graphs are…

Optimization and Control · Mathematics 2020-03-03 Peng Lin , Wei Ren , Chunhua Yang , Weihua Gui

Despite broad interest in self-organizing systems, there are few quantitative, experimentally-applicable criteria for self-organization. The existing criteria all give counter-intuitive results for important cases. In this Letter, we…

Adaptation and Self-Organizing Systems · Physics 2011-11-10 Cosma Rohilla Shalizi , Kristina Lisa Shalizi , Robert Haslinger

In this paper we describe a method to identify "relevant subsets" of variables, useful to understand the organization of a dynamical system. The variables belonging to a relevant subset should have a strong integration with the other…

Molecular Networks · Quantitative Biology 2015-02-09 Marco Villani , Andrea Roli , Alessandro Filisetti , Marco Fiorucci , Irene Poli , Roberto Serra

The field of complex networks studies a wide variety of interacting systems by representing them as networks. To understand their properties and mutual relations, the randomisation of network connections is a commonly used tool. However,…

Statistical Mechanics · Physics 2024-10-18 Noam Abadi , Franco Ruzzenenti

A dynamical system may be defined by a simple transition law - such as a map or a vector field. The objective of most learning techniques is to reconstruct this dynamic transition law. This is a major shortcoming, as most dynamic properties…

Dynamical Systems · Mathematics 2024-09-10 Suddhasattwa Das

We study policy optimization problems for deterministic Markov decision processes (MDPs) with metric state and action spaces, which we refer to as Metric Policy Optimization Problems (MPOPs). Our goal is to establish theoretical results on…

Optimization and Control · Mathematics 2022-07-14 Victor D. Dorobantu , Kamyar Azizzadenesheli , Yisong Yue

Rare event sampling is a central problem in modern computational chemistry research. Among the existing methods, transition path sampling (TPS) can generate unbiased representations of reaction processes. However, its efficiency depends on…

Computational Physics · Physics 2024-04-04 Jintu Zhang , Odin Zhang , Luigi Bonati , TingJun Hou

Self-optimizing control is a strategy for selecting controlled variables, where the economic objective guides the selection and design of controlled variables, with the expectation that maintaining the controlled variables at constant…

Optimization and Control · Mathematics 2026-05-08 Chenchen Zhou , Shaoqi Wang , Hongxin Su , Xinhui Tang , Yi Cao , Shuang-Hua Yang

Collective variables (CVs) are low-dimensional projections of high-dimensional system states. They are used to gain insights into complex emergent dynamical behaviors of processes on networks. The relation between CVs and network measures…

Physics and Society · Physics 2026-03-19 Marvin Lücke , Stefanie Winkelmann , Jobst Heitzig , Nora Molkenthin , Péter Koltai

A new data-enabled control technique for uncertain linear time-invariant systems, recently conceived by Coulson et\ al., builds upon the direct optimization of controllers over input/output pairs drawn from a large dataset. We adopt an…

Systems and Control · Electrical Eng. & Systems 2020-09-29 Filippo Fabiani , Paul J. Goulart

An accurate description of nonadiabatic dynamics of molecular species on metallic surfaces poses a serious computational challenge associated with a multitude of closely-spaced electronic states. We propose a mixed quantum-classical scheme…

Chemical Physics · Physics 2017-01-10 Ilya G. Ryabinkin , Artur F. Izmaylov

The design space of discrete-space diffusion or flow generative models are significantly less well-understood than their continuous-space counterparts, with many works focusing only on a simple masked construction. In this work, we aim to…

The chapter presents some new approaches to describing the collective behavior of complex systems of mathematical biology based on the evolution equations of observables such as open systems. This representation of kinetic evolution has…

Mathematical Physics · Physics 2025-03-18 V. I. Gerasimenko

Collective variables (CVs) play a crucial role in capturing rare events in high-dimensional systems, motivating the continual search for principled approaches to their design. In this work, we revisit the framework of quantitative coarse…

Numerical Analysis · Mathematics 2025-06-06 Shashank Sule , Arnav Mehta , Maria K. Cameron