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Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Language models have emerged as a critical area of focus in artificial intelligence, particularly with the introduction of groundbreaking innovations like ChatGPT. Large-scale Transformer networks have quickly become the leading approach…

Artificial Intelligence · Computer Science 2024-12-12 Wei Wang , Qing Li

With the broader adoption and highly successful development of Large Language Models (LLMs), there has been growing interest and demand for applying LLMs to autonomous driving technology. Driven by their natural language understanding and…

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

Large Language Models (LLMs) have demonstrated their transformative potential across numerous disciplinary studies, reshaping the existing research methodologies and fostering interdisciplinary collaboration. However, a systematic…

Computation and Language · Computer Science 2025-07-14 Lu Xiang , Yang Zhao , Yaping Zhang , Chengqing Zong

Modern transportation systems face pressing challenges due to increasing demand, dynamic environments, and heterogeneous information integration. The rapid evolution of Large Language Models (LLMs) offers transformative potential to address…

Artificial Intelligence · Computer Science 2025-06-24 Tong Nie , Jian Sun , Wei Ma

As organizations increasingly seek to leverage machine learning (ML) capabilities, the technical complexity of implementing ML solutions creates significant barriers to adoption and impacts operational efficiency. This research examines how…

Human-Computer Interaction · Computer Science 2025-07-09 Jiapeng Yao , Lantian Zhang , Jiping Huang

The 6G wireless communications aim to establish an intelligent world of ubiquitous connectivity, providing an unprecedented communication experience. Large artificial intelligence models (LAMs) are characterized by significantly larger…

Information Theory · Computer Science 2025-05-07 Feibo Jiang , Cunhua Pan , Li Dong , Kezhi Wang , Merouane Debbah , Dusit Niyato , Zhu Han

The rapid advancement of large language models (LLMs) has redefined artificial intelligence (AI), pushing the boundaries of AI research and enabling unbounded possibilities for both academia and the industry. However, LLM development faces…

Software Engineering · Computer Science 2025-07-01 Hongzhou Rao , Yanjie Zhao , Xinyi Hou , Shenao Wang , Haoyu Wang

The integration of Large Language Models (LLMs) into medical applications has sparked widespread interest across the healthcare industry, from drug discovery and development to clinical decision support, assisting telemedicine, medical…

Computation and Language · Computer Science 2024-12-03 Zifeng Wang , Hanyin Wang , Benjamin Danek , Ying Li , Christina Mack , Hoifung Poon , Yajuan Wang , Pranav Rajpurkar , Jimeng Sun

Recent developments in large language models (LLMs) have unlocked new opportunities for healthcare, from information synthesis to clinical decision support. These new LLMs are not just capable of modeling language, but can also act as…

Human-Computer Interaction · Computer Science 2023-09-21 Nikita Mehandru , Brenda Y. Miao , Eduardo Rodriguez Almaraz , Madhumita Sushil , Atul J. Butte , Ahmed Alaa

Civil aviation is a cornerstone of global transportation and commerce, and ensuring its safety, efficiency and customer satisfaction is paramount. Yet conventional Artificial Intelligence (AI) solutions in aviation remain siloed and narrow,…

Artificial Intelligence · Computer Science 2026-01-19 Wenbin Li , Jingling Wu , Xiaoyong Lin. Jing Chen , Cong Chen

The field of machine learning (ML) has gained widespread adoption, leading to significant demand for adapting ML to specific scenarios, which is yet expensive and non-trivial. The predominant approaches towards the automation of solving ML…

Machine Learning · Computer Science 2024-02-20 Lei Zhang , Yuge Zhang , Kan Ren , Dongsheng Li , Yuqing Yang

Large Language Models (LLMs) have revolutionized various fields with their exceptional capabilities in understanding, processing, and generating human-like text. This paper investigates the potential of LLMs in advancing Network Intrusion…

Cryptography and Security · Computer Science 2025-07-08 Shuo Yang , Xinran Zheng , Xinchen Zhang , Jinfeng Xu , Jinze Li , Donglin Xie , Weicai Long , Edith C. H. Ngai

The rapid development of artificial intelligence has led to marked progress in the field. One interesting direction for research is whether Large Language Models (LLMs) can be integrated with structured knowledge-based systems. This…

Computation and Language · Computer Science 2025-05-02 Wenli Yang , Lilian Some , Michael Bain , Byeong Kang

Generative Artificial Intelligence (GAI) and the idea to use hierarchical models has been around for some years now. GAI has proved to be an extremely useful tool for Autonomous Vehicles (AVs). AVs need to perform robustly in their…

Systems and Control · Electrical Eng. & Systems 2025-01-22 Diomidis Katzourakis

The overwhelming success of GPT-4 in early 2023 highlighted the transformative potential of large language models (LLMs) across various sectors, including national security. This article explores the implications of LLM integration within…

Cryptography and Security · Computer Science 2024-07-08 William N. Caballero , Phillip R. Jenkins

This paper provides a comprehensive survey of the latest research on multilingual large language models (MLLMs). MLLMs not only are able to understand and generate language across linguistic boundaries, but also represent an important…

Computation and Language · Computer Science 2024-11-20 Shaolin Zhu , Supryadi , Shaoyang Xu , Haoran Sun , Leiyu Pan , Menglong Cui , Jiangcun Du , Renren Jin , António Branco , Deyi Xiong

The rapid progress of Multimodal Large Language Models(MLLMs) has transformed the AI landscape. These models combine pre-trained LLMs with various modality encoders. This integration requires a systematic understanding of how different…

Computation and Language · Computer Science 2025-06-06 Jisu An , Junseok Lee , Jeoungeun Lee , Yongseok Son

As the parameter size of Large Language Models (LLMs) continues to expand, there is an urgent need to address the scarcity of high-quality data. In response, existing research has attempted to make a breakthrough by incorporating Federated…

Machine Learning · Computer Science 2024-10-31 Chaochao Chen , Xiaohua Feng , Yuyuan Li , Lingjuan Lyu , Jun Zhou , Xiaolin Zheng , Jianwei Yin