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Medical Image Segmentation (MIS) plays a crucial role in medical therapy planning and robot navigation. Prototype learning methods in MIS focus on generating segmentation masks through pixel-to-prototype comparison. However, current…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Zhe Wang , Chang Yao

In-context learning (ICL) enables medical image segmentation models to adapt to new anatomical structures from limited examples, reducing the clinical annotation burden. However, standard ICL methods typically rely on dense, global…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 T. Camaret Ndir , Marco Reisert , Robin T. Schirrmeister

Progress in digital pathology is hindered by high-resolution images and the prohibitive cost of exhaustive localized annotations. The commonly used paradigm to categorize pathology images is patch-based processing, which often incorporates…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Thomas Stegmüller , Behzad Bozorgtabar , Antoine Spahr , Jean-Philippe Thiran

Early detection of skin cancers like melanoma is crucial to ensure high chances of survival for patients. Clinical application of Deep Learning (DL)-based Decision Support Systems (DSS) for skin cancer screening has the potential to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-03-10 Adriano Lucieri , Andreas Dengel , Sheraz Ahmed

Forensic pathology is critical in analyzing death manner and time from the microscopic aspect to assist in the establishment of reliable factual bases for criminal investigation. In practice, even the manual differentiation between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Chen Shen , Jun Zhang , Xinggong Liang , Zeyi Hao , Kehan Li , Fan Wang , Zhenyuan Wang , Chunfeng Lian

Multiple instance learning (MIL) has emerged as a popular method for classifying histopathology whole slide images (WSIs). Existing approaches typically rely on frozen pre-trained models to extract instance features, neglecting the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Yi Lin , Zhengjie Zhu , Kwang-Ting Cheng , Hao Chen

Few-shot learning has recently attracted wide interest in image classification, but almost all the current public benchmarks are focused on natural images. The few-shot paradigm is highly relevant in medical-imaging applications due to the…

Computer Vision and Pattern Recognition · Computer Science 2022-06-02 Fereshteh Shakeri , Malik Boudiaf , Sina Mohammadi , Ivaxi Sheth , Mohammad Havaei , Ismail Ben Ayed , Samira Ebrahimi Kahou

Since the emergence of the ImageNet dataset, the pretraining and fine-tuning approach has become widely adopted in computer vision due to the ability of ImageNet-pretrained models to learn a wide variety of visual features. However, a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Pablo Meseguer , Rocío del Amor , Adrian Colomer , Valery Naranjo

We propose a simple and efficient image classification architecture based on deep multiple instance learning, and apply it to the challenging task of caries detection in dental radiographs. Technically, our approach contributes in two ways:…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Benjamin Bergner , Csaba Rohrer , Aiham Taleb , Martha Duchrau , Guilherme De Leon , Jonas Almeida Rodrigues , Falk Schwendicke , Joachim Krois , Christoph Lippert

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Qian Zeng , Yihui Wang , Shu Yang , Yingxue Xu , Fengtao Zhou , Jiabo Ma , Dejia Cai , Zhengyu Zhang , Lijuan Qu , Yu Wang , Li Liang , Hao Chen

Deep learning has been widely accepted as a promising solution for medical image segmentation, given a sufficiently large representative dataset of images with corresponding annotations. With ever increasing amounts of annotated medical…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Philipp Fuernstahl , Orcun Goksel

For classifying digital whole slide images in the absence of pixel level annotation, typically multiple instance learning methods are applied. Due to the generic applicability, such methods are currently of very high interest in the…

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A. Fallowfield , Hideki Ueno , Hitoshi Tsuda , David J. Harrison , Hakan Bilen , Timothy J. Kendall

We propose a new formulation of Multiple-Instance Learning (MIL). In typical MIL settings, a unit of data is given as a set of instances called a bag and the goal is to find a good classifier of bags based on similarity from a single or…

Machine Learning · Computer Science 2018-12-11 Daiki Suehiro , Kohei Hatano , Eiji Takimoto , Shuji Yamamoto , Kenichi Bannai , Akiko Takeda

Histopathological images provide rich information for disease diagnosis. Large numbers of histopathological images have been digitized into high resolution whole slide images, opening opportunities in developing computational image analysis…

Image and Video Processing · Electrical Eng. & Systems 2020-11-06 Jiayun Li , Wenyuan Li , Anthony Sisk , Huihui Ye , W. Dean Wallace , William Speier , Corey W. Arnold

Whole Slide Image (WSI) classification relies on Multiple Instance Learning (MIL) with spatial patch features, yet existing methods struggle to capture global dependencies due to the immense size of WSIs and the local nature of patch…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Anthony Bilic , Guangyu Sun , Ming Li , Md Sanzid Bin Hossain , Yu Tian , Wei Zhang , Laura Brattain , Dexter Hadley , Chen Chen

Histopathological image classification is an important task in medical image analysis. Recent approaches generally rely on weakly supervised learning due to the ease of acquiring case-level labels from pathology reports. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Bodong Zhang , Hamid Manoochehri , Man Minh Ho , Fahimeh Fooladgar , Yosep Chong , Beatrice S. Knudsen , Deepika Sirohi , Tolga Tasdizen

Whole slide image (WSI) classification is a critical task in computational pathology. However, the gigapixel-size of such images remains a major challenge for the current state of deep-learning. Current methods rely on multiple-instance…

Computer Vision and Pattern Recognition · Computer Science 2023-10-04 Etienne Pochet , Rami Maroun , Roger Trullo

In whole slide images (WSIs) analysis, attention-based multi-instance learning (MIL) models are susceptible to spurious correlations and degrade under domain shift. These methods may assign high attention weights to non-tumor regions, such…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Xin Liu , Weijia Zhang , Wei Tang , Thuc Duy Le , Jiuyong Li , Lin Liu , Min-Ling Zhang

Medical image segmentation poses challenges due to domain gaps, data modality variations, and dependency on domain knowledge or experts, especially for low- and middle-income countries (LMICs). Whereas for humans, given a few exemplars…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Chen Xu , Qiming Huang , Yuqi Hou , Jiangxing Wu , Fan Zhang , Hyung Jin Chang , Jianbo Jiao
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