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Related papers: Generic multicomponent mixtures are multistable

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Understanding how multi-component liquid mixtures undergo phase separation is central to elucidating biophysical organization in the cell. Here, combining analytical and numerical results, we characterise the dynamics of mixtures with…

Soft Condensed Matter · Physics 2026-02-06 Giacomo Bartolucci , Fabrizio Olmeda

Biological mixtures such as the cytosol may consist of thousands of distinct components. There is now a substantial body of evidence showing that, under physiological conditions, intracellular mixtures can phase separate into spatially…

Soft Condensed Matter · Physics 2017-03-06 William M. Jacobs , Daan Frenkel

We unravel the existence and stability properties of one-dimensional droplets arising in genuine two-component particle imbalanced bosonic mixtures under the influence of a weak harmonic confinement. A plethora of miscible droplet phases is…

Quantum Gases · Physics 2025-02-04 Efstathios G. Charalampidis , Simeon I. Mistakidis

Biomolecular condensates constitute a newly recognized form of spatial organization in living cells. Although many condensates are believed to form as a result of phase separation, the physicochemical properties that determine the phase…

Biological Physics · Physics 2023-07-11 William M. Jacobs

Biomolecular condensates self-assemble when proteins and nucleic acids spontaneously demix to form droplets within the crowded intracellular milieu. This simple mechanism underlies the formation of a wide variety of membraneless…

Statistical Mechanics · Physics 2021-06-30 William M. Jacobs

Biomolecules composed of a limited set of chemical building blocks can co-localize into distinct, spatially segregated compartments known as biomolecular condensates. While many condensates are known to form spontaneously via phase…

Soft Condensed Matter · Physics 2024-08-15 Fan Chen , William M. Jacobs

Phase separation, crucial for spatially segregating biomolecules in cells, is well-understood in the simple case of a few components with pairwise interactions. Yet, biological cells challenge the simple picture in at least two ways: First,…

Soft Condensed Matter · Physics 2024-03-12 Chengjie Luo , Yicheng Qiang , David Zwicker

We explore the ground state properties and excitation spectra of one-dimensional three-component bosonic mixtures accommodating a droplet in two of the species and a third minority component. Relying on the suitable Lee-Huang-Yang…

Quantum Gases · Physics 2026-01-09 I. A. Englezos , E. G. Charalampidis , P. Schmelcher , S. I. Mistakidis

We present a detailed numerical study of multi-component colloidal gels interacting sterically and obtained by arrested phase separation. Under deformation, we found that the interplay between the different intertwined networks is key.…

Soft Condensed Matter · Physics 2020-06-11 Claudia Ferreiro-Cordova , Mehdi Bouzid , Emanuela Del Gado , Giuseppe Foffi

Inside every living cell is the cytoplasm: a fluid mixture of thousands of different macromolecules, predominantly proteins. This mixture is where most of the biochemistry occurs that enables living cells to function, and it is perhaps the…

Soft Condensed Matter · Physics 2009-11-11 Richard P. Sear

Inside living cells are complex mixtures of thousands of components. It is hopeless to try to characterise all the individual interactions in these mixtures. Thus, we develop a statistical approach to approximating them, and examine the…

Soft Condensed Matter · Physics 2007-05-23 Richard P. Sear , Jose A. Cuesta

Understanding the phase behavior of mixtures with many components is important in many contexts, including as a key step toward a physics-based description of intracellular compartmentalization. Here, we study the instabilities of a mixture…

Statistical Mechanics · Physics 2023-08-16 Filipe C Thewes , Matthias Krüger , Peter Sollich

We study the thermodynamics of binary mixtures with the volume fraction of the minority component less than the amount required to form a flat interface and show that the surface tension dominated equilibrium phase of the mixture forms a…

Soft Condensed Matter · Physics 2023-03-07 Subhadip Biswas , Biswaroop Mukherjee , Buddhapriya Chakrabarti

Theoretical work has shed light on the phase behavior of idealized mixtures of many components with random interactions. But typical mixtures interact through particular physical features, leading to a structured, non-random interaction…

Statistical Mechanics · Physics 2022-09-05 Isabella R. Graf , Benjamin B. Machta

This paper presents a thermodynamically consistent model for multicomponent electrolyte solutions. The first part of this paper derives the general governing equations for nonequilibrium systems within the theory of nonequilibrium…

Analysis of PDEs · Mathematics 2016-05-25 Matthias Herz , Peter Knabner

Considering both interspecies and intraspecies fluctuations in ultracold bose-bose mixtures, we derive generalized stability conditions against collapse and phase separation. Furthermore, by examining the energy density of the system, we…

Quantum Physics · Physics 2023-08-29 Benarous Mohamed , Hocine Ahmed , Mehedi Atika

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

Multicomponent systems are ubiquitous in nature and industry. While the physics of few-component liquid mixtures (i.e., binary and ternary ones) is well-understood and routinely taught in undergraduate courses, the thermodynamic and kinetic…

Soft Condensed Matter · Physics 2019-10-07 Sheng Mao , Derek Kuldinow , Mikko P. Haataja , Andrej Kosmrlj

Virtually every biological function emerges through the organization of molecules in time and space. Consequently, a major challenge in statistical physics is to uncover the universal principles governing macromolecular self-organization…

Statistical Mechanics · Physics 2026-03-16 E. Meyberg , J. F. Robinson , T. Speck

We introduce a model of chemically active particles of a multi-component fluid that can change their interactions with other particles depending on their state. Since such switching of interactions can only be maintained by the input of…

Soft Condensed Matter · Physics 2019-05-01 Dino Osmanovic , Yitzhak Rabin
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