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Although recent advances in scaling large language models (LLMs) have resulted in improvements on many NLP tasks, it remains unclear whether these models trained primarily with general web text are the right tool in highly specialized,…

Efficient on-device language models around 1 billion parameters are essential for powering low-latency AI applications on mobile and wearable devices. However, achieving strong performance in this model class, while supporting long context…

Large Language Models (LLMs) are often proposed as tools to streamline clinical documentation, a task viewed as both high-volume and low-risk. However, even seemingly straightforward applications of LLMs raise complex sociotechnical…

Human-Computer Interaction · Computer Science 2025-09-05 Kristina L. Kupferschmidt , Kieran O'Doherty , Joshua A. Skorburg

Decision-making is a complex process requiring diverse abilities, making it an excellent framework for evaluating Large Language Models (LLMs). Researchers have examined LLMs' decision-making through the lens of Game Theory. However,…

Artificial Intelligence · Computer Science 2025-03-07 Jen-tse Huang , Eric John Li , Man Ho Lam , Tian Liang , Wenxuan Wang , Youliang Yuan , Wenxiang Jiao , Xing Wang , Zhaopeng Tu , Michael R. Lyu

The unstructured nature of clinical notes within electronic health records often conceals vital patient-related information, making it challenging to access or interpret. To uncover this hidden information, specialized Natural Language…

Biomedical literature often uses complex language and inaccessible professional terminologies. That is why simplification plays an important role in improving public health literacy. Applying Natural Language Processing (NLP) models to…

Computation and Language · Computer Science 2024-03-19 Zihao Li , Samuel Belkadi , Nicolo Micheletti , Lifeng Han , Matthew Shardlow , Goran Nenadic

This study assesses the ability of state-of-the-art large language models (LLMs) including GPT-3.5, GPT-4, Falcon, and LLaMA 2 to identify patients with mild cognitive impairment (MCI) from discharge summaries and examines instances where…

This work presents AdditiveLLM2 a multi-modal, domain adapted large language model built upon the instruction tuned variant of the Gemma 3 model using a relatively small dataset of around 50 million tokens. The dataset (AdditiveLLM2-OA)…

Machine Learning · Computer Science 2026-03-24 Peter Pak , Amir Barati Farimani

In this study, we aimed to determine if fine-tuned large language models (LLMs) can generate accurate, personalized impressions for whole-body PET reports. Twelve language models were trained on a corpus of PET reports using the…

As large language models (LLMs) like OpenAI's GPT series continue to make strides, we witness the emergence of artificial intelligence applications in an ever-expanding range of fields. In medicine, these LLMs hold considerable promise for…

Instruction-based Large Language Models (LLMs) have proven effective in numerous few-shot or zero-shot Natural Language Processing (NLP) tasks. However, creating human-annotated instruction data is time-consuming, expensive, and often…

Computation and Language · Computer Science 2025-05-13 Aniruddha Roy , Pretam Ray , Abhilash Nandy , Somak Aditya , Pawan Goyal

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Large Language Models (LLMs) have demonstrated remarkable adaptability, showcasing their capacity to excel in tasks for which they were not explicitly trained. However, despite their impressive natural language processing (NLP)…

Computation and Language · Computer Science 2023-09-08 Supun Manathunga , Isuru Hettigoda

Large language model (LLM) agents extend generative models with reasoning, tool use, and persistent memory, thereby enabling the automation of complex tasks. In healthcare, such systems could support documentation, care coordination, and…

Artificial Intelligence · Computer Science 2026-03-24 Wenxian Yang , Hanzheng Qiu , Bangqun Zhang , Chengquan Li , Zhiyong Huang , Xiaobin Feng , Rongshan Yu , Jiahong Dong

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Large Language Models (LLMs), particularly those similar to ChatGPT, have significantly influenced the field of Natural Language Processing (NLP). While these models excel in general language tasks, their performance in domain-specific…

Computation and Language · Computer Science 2024-01-02 Omid Rohanian , Mohammadmahdi Nouriborji , David A. Clifton

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

Large language models (LLMs) have shown amazing capabilities in knowledge memorization and the present. However, when it comes to domain-specific knowledge and downstream tasks like medical, general LLMs are often unable to give precise…

Computation and Language · Computer Science 2024-06-06 Maojun Sun