Related papers: New Trends on the Systems Approach to Modeling SAR…
The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…
The coronavirus disease (COVID-19) pandemic has changed our lives and still poses a challenge to science. Numerous studies have contributed to a better understanding of the pandemic. In particular, inhalation of aerosolised pathogens has…
In this work, we derive a system of Boltzmann-type equations to describe the spread of SARS-CoV-2 virus at the microscopic scale, that is by modeling the human-to-human mechanisms of transmission. To this end, we consider two populations,…
More than any other infectious disease epidemic, the COVID-19 pandemic has been characterized by the generation of large volumes of viral genomic data at an incredible pace due to recent advances in high-throughput sequencing technologies,…
During the COVID-19 pandemic, community containment measures have been implemented in different parts of the world. However, despite government recommendations and mandates, a progressive increase in mobility was observed in several sites.…
Infectious epidemics can be simulated by employing dynamical processes as interactions on network structures. Here, we introduce techniques from the Multi-Agent System (MAS) domain in order to account for individual level characterization…
Severe Acute Respiratory Syndrome-CoronaVirus 2 (SARS-CoV2) caused the ongoing pandemic. This pandemic devastated the world by killing more than a million people, as of October 2020. It is imperative to understand the transmission dynamics…
Pandemics can cause immense disruption and damage to communities and societies. Thus far, modeling of pandemics has focused on either large-scale difference equation models like the SIR and the SEIR models, or detailed micro-level…
In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…
A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dynamics to provide…
Computational multi-scale pandemic modelling remains a major and timely challenge. Here we identify specific requirements for a new class of models simulating pandemics across three scales: (1) pathogen evolution, often punctuated by the…
In this work we propose the design principles of a stochastic graph-based model for the simulation of SARS-CoV-2 transmission. The proposed approach incorporates three sub-models, namely, the spatial model, the mobility model, and the…
Interactions between SARS-CoV-2 and the immune system during infection are complex. However, understanding the within-host SARS-CoV-2 dynamics is of enormous importance, especially when it comes to assessing treatment options. Mathematical…
There is a growing interest in modeling and analyzing the spread of diseases like the SARS-CoV-2 infection using stochastic models. These models are typically analyzed quantitatively and are not often subject to validation using formal…
Stochastic differential equations characterized by uncertainty are effective in modelling virus dynamics and provide an alternative to traditional deterministic models. Epidemic models are inevitably subjected to the randomness within the…
The present work shows that it is possible to analytically solve a general model to explain the transmission dynamics of SARS-CoV-2. First, the within-host model is described, and later a between-host model, where the coupling between them…
The dynamics of epidemics depend on how people's behavior changes during an outbreak. At the beginning of the epidemic, people do not know about the virus, then, after the outbreak of epidemics and alarm, they begin to comply with the…
We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…
The dynamics of the spread of contagions such as viruses, infectious diseases or even rumors/opinions over contact networks (graphs) have effectively been captured by the well known \textit{Susceptible-Infected-Susceptible} ($SIS$) epidemic…
In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…