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Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

Medical Physics · Physics 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang

Accurately translating medical images between different modalities, such as Computed Tomography (CT) to Magnetic Resonance Imaging (MRI), has numerous downstream clinical and machine learning applications. While several methods have been…

Image and Video Processing · Electrical Eng. & Systems 2025-12-03 Yuwen Chen , Nicholas Konz , Hanxue Gu , Haoyu Dong , Yaqian Chen , Lin Li , Jisoo Lee , Maciej A. Mazurowski

Dynamic cone-beam computed tomography (CBCT) can capture high-spatial-resolution, time-varying images for motion monitoring, patient setup, and adaptive planning of radiotherapy. However, dynamic CBCT reconstruction is an extremely…

Medical Physics · Physics 2023-12-05 Hua-Chieh Shao , Mengke Tielige , Tinsu Pan , You Zhang

Deformable medical image registration is an essential task in computer-assisted interventions. This problem is particularly relevant to oncological treatments, where precise image alignment is necessary for tracking tumor growth, assessing…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Stefano Fogarollo , Gregor Laimer , Reto Bale , Matthias Harders

Intra-fraction motion in radiotherapy is commonly modeled using deformable image registration (DIR). However, existing methods often struggle to balance speed and accuracy, limiting their applicability in clinical scenarios. This study…

Medical Physics · Physics 2024-02-09 Xia Li , Fabian Zhang , Muheng Li , Damien Weber , Antony Lomax , Joachim Buhmann , Ye Zhang

Deformable image registration (DIR) is a crucial and challenging technique for aligning anatomical structures in medical images and is widely applied in diverse clinical applications. However, existing approaches often struggle to capture…

Image and Video Processing · Electrical Eng. & Systems 2025-08-26 Shayan Kebriti , Shahabedin Nabavi , Ali Gooya

Deformable image registration (DIR) is an enabling technology in many diagnostic and therapeutic tasks. Despite this, DIR algorithms have limited clinical use, largely due to a lack of benchmark datasets for quality assurance during…

Computer Vision and Pattern Recognition · Computer Science 2025-01-17 Edward R Criscuolo , Yao Hao , Zhendong Zhang , Trevor McKeown , Deshan Yang

Deformable image registration (DIR) involves optimization of multiple conflicting objectives, however, not many existing DIR algorithms are multi-objective (MO). Further, while there has been progress in the design of deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Monika Grewal , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

Dynamic magnetic resonance imaging (dMRI) captures temporally-resolved anatomy but is often challenged by limited sampling and motion-induced artifacts. Conventional motion-compensated reconstructions typically rely on pre-estimated optical…

Computer Vision and Pattern Recognition · Computer Science 2025-11-24 Baoqing Li , Yuanyuan Liu , Congcong Liu , Qingyong Zhu , Jing Cheng , Yihang Zhou , Hao Chen , Zhuo-Xu Cui , Dong Liang

Temporal echocardiography image registration is a basis for clinical quantifications such as cardiac motion estimation, myocardial strain assessments, and stroke volume quantifications. In past studies, deep learning image registration…

Image and Video Processing · Electrical Eng. & Systems 2023-09-12 Md. Kamrul Hasan , Haobo Zhu , Guang Yang , Choon Hwai Yap

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

Learning-based deformable image registration (DIR) accelerates alignment by amortizing traditional optimization via neural networks. Label supervision further enhances accuracy, enabling efficient and precise nonlinear alignment of unseen…

Computer Vision and Pattern Recognition · Computer Science 2025-06-13 Hang Zhang , Xiang Chen , Renjiu Hu , Rongguang Wang , Jinwei Zhang , Min Liu , Yaonan Wang , Gaolei Li , Xinxing Cheng , Jinming Duan

Supervised Deep-Learning (DL)-based reconstruction algorithms have shown state-of-the-art results for highly-undersampled dynamic Magnetic Resonance Imaging (MRI) reconstruction. However, the requirement of excessive high-quality…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jie Feng , Ruimin Feng , Qing Wu , Zhiyong Zhang , Yuyao Zhang , Hongjiang Wei

Current state-of-the-art motion-based dynamic computed tomography reconstruction techniques estimate the deformation by considering motion models in the entire object volume although occasionally the proper change is local. In this article,…

Optimization and Control · Mathematics 2023-09-06 Anh-Tuan Nguyen , Jens Renders , Jan Sijbers , Jan De Beenhouwer

Online adaptive radiation therapy (ART) promises the ability to deliver an optimal treatment in response to daily patient anatomic variation. A major technical barrier for the clinical implementation of online ART is the requirement of…

Dynamic MRI reconstruction, one of inverse problems, has seen a surge by the use of deep learning techniques. Especially, the practical difficulty of obtaining ground truth data has led to the emergence of unsupervised learning approaches.…

Image and Video Processing · Electrical Eng. & Systems 2025-10-28 Dayoung Baik , Jaejun Yoo

A precise spatial delivery of the radiation dose is crucial for the treatment success in radiotherapy. In the lung and upper abdominal region, respiratory motion introduces significant treatment uncertainties, requiring special motion…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Jan Boysen , Hristina Uzunova , Heinz Handels , Jan Ehrhardt

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Evaluating deformable image registration (DIR) is challenging due to the inherent trade-off between achieving high alignment accuracy and maintaining deformation regularity. However, most existing DIR works either address this trade-off…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Vasiliki Sideri-Lampretsa , Daniel Rueckert , Huaqi Qiu

Deformable Image Registration (DIR) plays a significant role in quantifying deformation in medical data. Recent Deep Learning methods have shown promising accuracy and speedup for registering a pair of medical images. However, in 4D (3D +…

Image and Video Processing · Electrical Eng. & Systems 2023-05-26 Xiao Liang , Shan Lin , Fei Liu , Dimitri Schreiber , Michael Yip