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We consider the problem of inferring the functional connectivity of a large-scale computer network from sparse time series of events emitted by its nodes. We do so under the following three domain-specific constraints: (a) non-stationarity…

Machine Learning · Computer Science 2018-02-13 Antoine Messager , George Parisis , Istvan Z Kiss , Robert Harper , Phil Tee , Luc Berthouze

Connectivity estimation is challenging in the context of high-dimensional data. A useful preprocessing step is to group variables into clusters, however, it is not always clear how to do so from the perspective of connectivity estimation.…

Machine Learning · Statistics 2018-05-25 Ricardo Pio Monti , Aapo Hyvärinen

Exploring how genetic sequences shape phenotypes is a fundamental challenge in biology and a key step toward scalable, hypothesis-driven experimentation. The task is complicated by the large modality gap between sequences and phenotypes, as…

Machine Learning · Computer Science 2025-11-18 Jingquan Yan , Yuwei Miao , Lei Yu , Yuzhi Guo , Xue Xiao , Lin Xu , Junzhou Huang

Big data initiatives such as the Enhancing NeuroImaging Genetics through Meta-Analysis consortium (ENIGMA), combine data collected by independent studies worldwide to achieve more accurate estimates of effect sizes and more reliable and…

Quantitative estimation of information flow in early vision with psychophysically realistic networks is still an open issue. This is because, up to date, the necessary elements (general and plausible network, accurate noise, and reliable…

Neurons and Cognition · Quantitative Biology 2026-03-31 Javier Rodríguez , Raquel Giménez , Jesús Malo

Randomly connected neural networks have long served as a theoretical tool for studying collective dynamics in neural populations, yet quantitative comparisons to experiments remain limited. Recent technological advances have made it…

Neurons and Cognition · Quantitative Biology 2026-05-27 Zehui Zhao , Michael J Pasek , Ilya M Nemenman

Densely Connected Convolutional Networks (DenseNets) have been shown to achieve state-of-the-art results on image classification tasks while using fewer parameters and computation than competing methods. Since each layer in this…

Computer Vision and Pattern Recognition · Computer Science 2018-06-07 Andy Hess

We investigate whether and how we can improve the cost efficiency of neuroimaging studies with well-tailored fMRI tasks. The comparative study is conducted using a novel network science-driven Bayesian connectome-based predictive method,…

Applications · Statistics 2024-11-05 Xinzhi Zhang , Leslie A Hulvershorn , Todd Constable , Yize Zhao , Selena Wang

We study the problem of discovering functional dependencies (FD) from a noisy dataset. We focus on FDs that correspond to statistical dependencies in a dataset and draw connections between FD discovery and structure learning in…

Databases · Computer Science 2019-05-07 Zhihan Guo , Theodoros Rekatsinas

While existing predictive frameworks are able to handle Euclidean structured data (i.e, brain images), they might fail to generalize to geometric non-Euclidean data such as brain networks. Besides, these are rooted the sample selection step…

Computer Vision and Pattern Recognition · Computer Science 2020-09-24 Ahmet Serkan Goktas , Alaa Bessadok , Islem Rekik

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Federated learning is a machine learning paradigm that leverages edge computing on client devices to optimize models while maintaining user privacy by ensuring that local data remains on the device. However, since all data is collected by…

Machine Learning · Computer Science 2025-06-11 Jingqiao Tang , Ryan Bausback , Feng Bao , Richard Archibald

Prior-Fitted Networks (PFNs) amortize Bayesian prediction by meta-learning over a synthetic task prior, but their standard output is a posterior predictive distribution over noisy observations. For sequential decision-making, such as active…

Machine Learning · Statistics 2026-05-08 Richard Bergna , Stefan Depeweg , José Miguel Hernández-Lobato

Resting-state functional MRI (rs-fMRI) is widely used to noninvasively study human brain networks. Network functional connectivity is often estimated by calculating the timeseries correlation between blood-oxygen-level dependent (BOLD)…

Quantitative Methods · Quantitative Biology 2017-01-25 Nan Xu , R. Nathan Spreng , Peter C. Doerschuk

A fundamental challenge in neuroscience is to decode mental states from brain activity. While functional magnetic resonance imaging (fMRI) offers a non-invasive approach to capture brain-wide neural dynamics with high spatial precision,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-31 Yueh-Po Peng , Vincent K. M. Cheung , Li Su

Children with rare genetic diseases often exhibit distinctive facial phenotypes, yet developing computer vision systems for early diagnosis remains challenging due to extreme data scarcity, privacy constraints, and limited data sharing in…

Computer Vision and Pattern Recognition · Computer Science 2026-05-22 Ganlin Feng , Yuxi Long , Erin Lou , Lianghong Chen , Zihao Jing , Pingzhao Hu , Wei Xu

Network models are widely used to represent relational information among interacting units and the structural implications of these relations. Recently, social network studies have focused a great deal of attention on random graph models of…

Applications · Statistics 2010-10-06 Mark S. Handcock , Krista J. Gile

Structural information of phylogenetic tree topologies plays an important role in phylogenetic inference. However, finding appropriate topological structures for specific phylogenetic inference tasks often requires significant design effort…

Machine Learning · Statistics 2023-02-20 Cheng Zhang

It is widely believed that the success of deep networks lies in their ability to learn a meaningful representation of the features of the data. Yet, understanding when and how this feature learning improves performance remains a challenge:…

Machine Learning · Statistics 2022-10-13 Leonardo Petrini , Francesco Cagnetta , Eric Vanden-Eijnden , Matthieu Wyart

Multivariate dynamical processes can often be intuitively described by a weighted connectivity graph between components representing each individual time-series. Even a simple representation of this graph as a Pearson correlation matrix may…

Machine Learning · Computer Science 2022-02-15 Usman Mahmood , Zening Fu , Vince Calhoun , Sergey Plis
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