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We introduce Causal Computational Asymmetry (CCA), a principle for causal direction identification based on optimization dynamics in which one neural network is trained to predict $Y$ from $X$ and another to predict $X$ from $Y$, and the…

Machine Learning · Computer Science 2026-02-27 Abdulrahman Tamim

There has been a split in the statistics community about the need for taking covariates into account in the design phase of a clinical trial. There are many advocates of using stratification and covariate-adaptive randomization to promote…

Methodology · Statistics 2011-02-21 William F. Rosenberger , Oleksandr Sverdlov

Dynamic treatment regimens (DTRs), also known as treatment algorithms or adaptive interventions, play an increasingly important role in many health domains. DTRs are motivated to address the unique and changing needs of individuals by…

Stepped wedge cluster randomized trials (SW-CRTs) have become increasingly popular and are used for a variety of interventions and outcomes, often chosen for their feasibility advantages. SW-CRTs must account for time trends in the outcome…

Methodology · Statistics 2024-07-16 Lee Kennedy-Shaffer , Victor De Gruttola , Marc Lipsitch

Clustering is a core task in machine learning with wide-ranging applications in data mining and pattern recognition. However, its unsupervised nature makes it inherently challenging. Many existing clustering algorithms suffer from critical…

Machine Learning · Computer Science 2025-07-29 Ahmed Shokry , Ayman Khalafallah

The presence of interference, where the outcome of an individual may depend on the treatment assignment and behavior of neighboring nodes, can lead to biased causal effect estimation. Current approaches to network experiment design focus on…

Machine Learning · Computer Science 2024-05-22 Zahra Fatemi , Jean Pouget-Abadie , Elena Zheleva

This paper studies a factor modeling-based approach for clustering high-dimensional data generated from a mixture of strongly correlated variables. Statistical modeling with correlated structures pervades modern applications in economics,…

Statistics Theory · Mathematics 2024-08-23 Shange Tang , Soham Jana , Jianqing Fan

In real-world continual learning (CL) scenarios, tasks often exhibit intricate and unpredictable semantic shifts, posing challenges for fixed prompt management strategies which are tailored to only handle semantic shifts of uniform degree…

Machine Learning · Computer Science 2024-07-23 Doyoung Kim , Susik Yoon , Dongmin Park , Youngjun Lee , Hwanjun Song , Jihwan Bang , Jae-Gil Lee

This article develops design-based ratio estimators for clustered, blocked randomized controlled trials (RCTs), with an application to a federally funded, school-based RCT testing the effects of behavioral health interventions. We consider…

Methodology · Statistics 2024-05-31 Peter Z. Schochet , Nicole E. Pashley , Luke W. Miratrix , Tim Kautz

In pragmatic cluster randomized controlled trials (PCRCTs), healthcare providers are randomized while both providers and patients may deviate from the assigned intervention. In many PCRCTs, cluster-level implementation is measured using…

Applications · Statistics 2026-04-29 Anthony Sisti , Ellen McCreedy , Roee Gutman

Fast accumulation of large amounts of complex data has created a need for more sophisticated statistical methodologies to discover interesting patterns and better extract information from these data. The large scale of the data often…

Methodology · Statistics 2014-09-09 Yuliya Marchetti , Qing Zhou

Both cluster randomized trials and quasi-experimental designs are used to evaluate the impact of health and social policies and interventions. Stepped-wedge cluster randomized trials randomize a staggered adoption approach, while recent…

Methodology · Statistics 2026-04-15 Haidong Lu , Gregg S. Gonsalves , Fan Li , Guanyu Tong , Lee Kennedy-Shaffer

Finetuning large language models on instruction data is crucial for enhancing pre-trained knowledge and improving instruction-following capabilities. As instruction datasets proliferate, selecting optimal data for effective training becomes…

Computation and Language · Computer Science 2024-09-18 Simon Yu , Liangyu Chen , Sara Ahmadian , Marzieh Fadaee

Models for dependent data are distinguished by their targets of inference. Marginal models are useful when interest lies in quantifying associations averaged across a population of clusters. When the functional form of a covariate-outcome…

Methodology · Statistics 2022-04-18 Glen McGee , Alex Stringer

Learning causal structure from observational data is especially challenging when latent variables or selection bias are present. The Fast Causal Inference (FCI) algorithm addresses this setting but performs exhaustive conditional…

Machine Learning · Computer Science 2025-11-06 Joseph Ramsey , Bryan Andrews , Peter Spirtes

The typical complexity of Constraint Satisfaction Problems (CSPs) can be investigated by means of random ensembles of instances. The latter exhibit many threshold phenomena besides their satisfiability phase transition, in particular a…

Disordered Systems and Neural Networks · Physics 2019-03-29 Louise Budzynski , Federico Ricci-Tersenghi , Guilhem Semerjian

Background: Advanced adaptive randomised clinical trials are increasingly used. Compared to their conventional counterparts, their flexibility may make them more efficient, increase the probability of obtaining conclusive results without…

Since autonomous driving systems usually face dynamic and ever-changing environments, continual test-time adaptation (CTTA) has been proposed as a strategy for transferring deployed models to continually changing target domains. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Jiayi Ni , Senqiao Yang , Ran Xu , Jiaming Liu , Xiaoqi Li , Wenyu Jiao , Zehui Chen , Yi Liu , Shanghang Zhang

Traditional covariate selection methods for causal inference focus on achieving unbiasedness and asymptotic efficiency. In many practical scenarios, researchers must estimate causal effects from observational data with limited sample sizes…

Statistics Theory · Mathematics 2025-06-17 Nadja Rutsch , Sara Magliacane , Stéphanie van der Pas

Latent variable models are popularly used to measure latent factors (e.g., abilities and personalities) from large-scale assessment data. Beyond understanding these latent factors, the covariate effect on responses controlling for latent…

Methodology · Statistics 2026-01-12 Jing Ouyang , Chengyu Cui , Kean Ming Tan , Gongjun Xu