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Electronic health record (EHR) data are increasingly used to support real-world evidence (RWE) studies. Yet its ability to generate reliable RWE is limited by the lack of readily available precise information on the timing of clinical…

The analysis of population-wide datasets can provide insight on the health status of large populations so that public health officials can make data-driven decisions. The analysis of such datasets often requires highly parameterized models…

Applications · Statistics 2021-02-03 Dorota Młynarczyk , Carmen Armero , Virgilio Gómez-Rubio , Pedro Puig

The Logical Execution Time (LET) model has been gaining industrial attention because of its timing and data-flow deterministic characteristics, which simplify the computation of end-to-end latencies of multi-rate cause-effect chains at the…

Systems and Control · Electrical Eng. & Systems 2024-07-30 Luiz Maia , Gerhard Fohler

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

Machine Learning · Statistics 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

Due to the presence of multiple types of adverse events with different levels of severity, the analysis of longitudinal toxicity data is a difficult task in cancer studies. In this work, a novel approach based on latent Markov models and…

Applications · Statistics 2024-12-05 Marta Spreafico , Francesca Ieva , Marta Fiocco

Individual events at high-energy colliders like the LHC can be represented by a sequence of measurements, or 'point patterns' in an observable space. Starting from this data representation, we build a simple Bayesian probabilistic model for…

High Energy Physics - Phenomenology · Physics 2020-12-17 Darius A. Faroughy

Subjective wellness data can provide important information on the well-being of athletes and be used to maximize player performance and detect and prevent against injury. Wellness data, which are often ordinal and multivariate, include…

Applications · Statistics 2020-05-20 Erin M. Schliep , Toryn L. J. Schafer , Matthew Hawkey

We propose autoregressive Bayesian semi-parametric models for waiting times between recurrent events. The aim is two-fold: inference on the effect of possibly time-varying covariates on the gap times and clustering of individuals based on…

Applications · Statistics 2016-07-28 Marta Tallarita , Maria De Iorio , Alessandra Guglielmi , James Malone-Lee

We introduce the SoftBart approach from Bayesian ensemble learning to estimate the relationship between multipollutant mixtures and health on chronic exposures in epidemiology research. This approach offers several key advantages over…

Quantitative Methods · Quantitative Biology 2025-05-26 Yu-Chien Ning , Xin Zhou , Francine Laden , Molin Wang

An important goal of environmental health research is to assess the health risks posed by mixtures of multiple environmental exposures. In these mixtures analyses, flexible models like Bayesian kernel machine regression and multiple index…

Methodology · Statistics 2025-12-29 Glen McGee , Joseph Antonelli

The present study aims to determine the lifetime prognosis of highly durable nondestructive one-shot devices (NOSD) units under a step-stress accelerated life testing (SSALT) experiment applying a cumulative risk model (CRM). In an SSALT…

Methodology · Statistics 2025-03-12 Shanya Baghel , Shuvashree Mondal

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a…

Capturing the inter-dependencies among multiple types of clinically-critical events is critical not only to accurate future event prediction, but also to better treatment planning. In this work, we propose a deep latent state-space…

Machine Learning · Computer Science 2024-07-30 Yuan Xue , Denny Zhou , Nan Du , Andrew M. Dai , Zhen Xu , Kun Zhang , Claire Cui

To effect behavior change a successful algorithm must make high-quality decisions in real-time. For example, a mobile health (mHealth) application designed to increase physical activity must make contextually relevant suggestions to…

Machine Learning · Statistics 2020-03-31 Marianne Menictas , Sabina Tomkins , Susan A Murphy

We introduce a rational inattention model which produces a unique, interior, weighted multinomial logit conditional choice probability for an agent who acquires costly information about the hedonic characteristics (e.g. whether an insurance…

Theoretical Economics · Economics 2026-01-27 Chris Engh

Many rare diseases offer limited established treatment options, leading patients to switch therapies when new medications emerge. To analyze the impact of such treatment switches within the low sample size limitations of rare disease…

In various data situations joint models are an efficient tool to analyze relationships between time dependent covariates and event times or to correct for event-dependent dropout occurring in regression analysis. Joint modeling connects a…

Methodology · Statistics 2018-10-25 Colin Griesbach , Andreas Mayr , Elisabeth Waldmann

Phase I dose-finding studies aim at identifying the maximal tolerated dose (MTD). It is not uncommon that several dose-finding studies are conducted, although often with some variation in the administration mode or dose panel. For instance,…

Quantitative Methods · Quantitative Biology 2021-03-24 Moreno Ursino , Christian Röver , Sarah Zohar , Tim Friede

The relationship between short-term exposure to air pollution and mortality or morbidity has been the subject of much recent research, in which the standard method of analysis uses Poisson linear or additive models. In this paper we use a…

Applications · Statistics 2012-01-27 Duncan Lee , Gavin Shaddick

To extend cognitive diagnostic models (CDMs) to longitudinal settings, stepwise approaches that integrate a CDM model with a latent transition model and covariates are widely used due to their flexibility. Previous research has shown that…

Methodology · Statistics 2026-04-20 Yawen Ma , Anastasia Ushakova , Kate Cain , Gabriel Wallin
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