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Standard regression adjustment gives inconsistent estimates of causal effects when there are time-varying treatment effects and time-varying covariates. Loosely speaking, the issue is that some covariates are post-treatment variables…

Methodology · Statistics 2024-03-12 Stephen Bates , Edward Kennedy , Robert Tibshirani , Valerie Ventura , Larry Wasserman

Effect size indices are useful parameters that quantify the strength of association and are unaffected by sample size. There are many available effect size parameters and estimators, but it is difficult to compare effect sizes across…

Computation · Statistics 2023-02-27 Megan Jones , Kaidi Kang , Simon Vandekar

Shape restrictions on functional regression coefficients such as non-negativity, monotonicity, convexity or concavity are often available in the form of a prior knowledge or required to maintain a structural consistency in functional…

Methodology · Statistics 2022-09-13 Rahul Ghosal , Sujit Ghosh , Jacek Urbanek , Jennifer A. Schrack , Vadim Zipunnikov

Prediction algorithms that quantify the expected benefit of a given treatment conditional on patient characteristics can critically inform medical decisions. Quantifying the performance of treatment benefit prediction algorithms is an…

Methodology · Statistics 2023-05-17 Yuan Xia , Paul Gustafson , Mohsen Sadatsafavi

Treatment effect estimation, which refers to the estimation of causal effects and aims to measure the strength of the causal relationship, is of great importance in many fields but is a challenging problem in practice. As present,…

Machine Learning · Computer Science 2021-07-20 Zhenyu Guo , Shuai Zheng , Zhizhe Liu , Kun Yan , Zhenfeng Zhu

Transformation models are a very important tool for applied statisticians and econometricians. In many applications, the dependent variable is transformed so that homogeneity or normal distribution of the error holds. In this paper, we…

Methodology · Statistics 2017-12-21 Sven Klaassen , Jannis Kueck , Martin Spindler

This paper develops power and sample size formulas for causal inference with time-to-event outcomes. The target estimand is the marginal hazard ratio: the coefficient of a marginal structural Cox proportional hazard model with treatment as…

Methodology · Statistics 2026-05-19 Chengxin Yang , Bo Liu , Fan Li

A new meta-algorithm for estimating the conditional average treatment effects is proposed in the paper. The main idea underlying the algorithm is to consider a new dataset consisting of feature vectors produced by means of concatenation of…

Machine Learning · Statistics 2019-09-10 Lev V. Utkin , Mikhail V. Kots , Viacheslav S. Chukanov

We propose a principal components regression method based on maximizing a joint pseudo-likelihood for responses and predictors. Our method uses both responses and predictors to select linear combinations of the predictors relevant for the…

Methodology · Statistics 2021-08-10 Karl Oskar Ekvall

Influence functions estimate the effect of removing a training point on a model without the need to retrain. They are based on a first-order Taylor approximation that is guaranteed to be accurate for sufficiently small changes to the model,…

Machine Learning · Computer Science 2019-11-22 Pang Wei Koh , Kai-Siang Ang , Hubert H. K. Teo , Percy Liang

In this note, an alternative for presenting the distribution of `significant' events in searches for new phenomena is described. The alternative is based on probability density functions used in the evaluation of the `significance' of an…

High Energy Physics - Experiment · Physics 2019-02-25 Nicholas Wardle

We use p-values to identify the threshold level at which a regression function takes off from its baseline value, a problem motivated by applications in toxicological and pharmacological dose-response studies and environmental statistics.…

Methodology · Statistics 2011-06-13 Atul Mallik , Bodhisattva Sen , Moulinath Banerjee , George Michailidis

Regressions are commonly used in environmental science and economics to identify causal or associative relationships between variables. In these settings, remote sensing-derived map products increasingly serve as sources of variables,…

Applications · Statistics 2025-07-04 Kerri Lu , Dan M. Kluger , Stephen Bates , Sherrie Wang

The coefficient of determination is well defined for linear models and its extension is long wanted for mixed-effects models. We revisit its extension to define measures for proportions of variation explained by the whole model, fixed…

Methodology · Statistics 2022-05-04 Dabao Zhang

Survey questions often ask respondents to select from ordered scales where the meanings of the categories are subjective, leaving each individual free to apply their own definitions in answering. This paper studies the use of these…

Econometrics · Economics 2025-01-29 Leonard Goff

Effect size estimates are thought to capture the collective, two-way response to an intervention or exposure in a three-way problem among the intervention/exposure, various confounders and the outcome. For meaningful causal inference from…

Methodology · Statistics 2024-02-08 Orestis Loukas , Ho Ryun Chung

Statisticians usually restrict regression to model relationships that are explicitly defined dependent and independent random variables; this paper outlines the newly developed method of non-response analysis and rotational analysis for…

Methodology · Statistics 2016-03-29 Rebecca D. Wooten

Evaluation of treatment effects and more general estimands is typically achieved via parametric modelling, which is unsatisfactory since model misspecification is likely. Data-adaptive model building (e.g. statistical/machine learning) is…

Statistics Theory · Mathematics 2022-01-14 Oliver Hines , Oliver Dukes , Karla Diaz-Ordaz , Stijn Vansteelandt

Meta-analysis can be formulated as combining $p$-values across studies into a joint $p$-value function, from which point estimates and confidence intervals can be derived. We extend the meta-analytic estimation framework based on combined…

Methodology · Statistics 2025-10-21 David Kronthaler , Leonhard Held

There are two distinct definitions of 'P-value' for evaluating a proposed hypothesis or model for the process generating an observed dataset. The original definition starts with a measure of the divergence of the dataset from what was…

Other Statistics · Statistics 2023-09-25 Sander Greenland
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