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Over the last decades, the use of magnetic nanoparticles in research and commercial applications has increased dramatically. However, direct detection of trace quantities remains a challenge in terms of equipment cost, operating conditions…

In drug discovery research there is a clear and urgent need for non-invasive detection of cell membrane ion channel operation with wide-field capability. Existing techniques are generally invasive, require specialized nano structures, or…

Preconcentration of the target compound is a critical step that ensures the accuracy of the subsequent chemical analysis. In this work, we present a straightforward yet effective liquid-liquid extraction approach based on surface…

Chemical Physics · Physics 2023-06-27 Hongyan Wu , Quynh Nhu Le , Binglin Zeng , Xuehua Zhang

The nitrogen-vacancy (NV) center in diamond is a prime candidate for quantum sensing technologies. Here, we present a fully integrated and mechanically robust fiber-based endoscopic sensor with a tip diameter of $1.25 \mathrm{mm}$. On its…

Ensembles of nitrogen-vacancy (NV) centers in diamond are versatile quantum sensors with broad applications in the physical and life sciences. The concentration of neutral substitutional nitrogen ([N$_\text{s}^0$]) strongly influences…

Naturally occurring paramagnetic species (PS), such as free radicals and paramagnetic metalloproteins, play an essential role in a multitude of critical physiological processes including metabolism, cell signaling and immune response. These…

We report progress toward a CMOS-integrated quantum diamond biosensing platform that combines nitrogen-vacancy (NV) centers in diamond with a custom 40 nm CMOS Single-Photon Avalanche Diode (SPAD) array. The system integrates on-chip active…

Fluorescent nanodiamonds (FNDs) have been exploited as sensitive quantum probes for nanoscale chemical and biological sensing applications, with the majority of demonstrations to date relying on the detection of single FNDs. This places…

The diamond sensor has emerged as a promising platform for quantum sensing, enabling the estimation of physical quantities -- such as microwave~(MW) field -- with precision unattainable by classical counterpart. However, traditional diamond…

Quantum Physics · Physics 2025-10-07 Qi-Tao Duan , Teng Li , Si-Qi Chen , Shengshi Pang , He Lu

Nitrogen-vacancy (NV) centers in nanodiamonds are excellent nanoscale sensors for measuring parameters such as temperature, magnetic field, and viscosity in complex fluidic environments, including living cells. However, the rapid motion of…

Fluorescent nanodiamonds (fNDs) containing Nitrogen Vacancy (NV) centres are promising candidates for quantum sensing in biological environments. However, to date, there has been little progress made to combine the sensing capabilities of…

Applied Physics · Physics 2018-12-06 J. C. Price , S. J. Levett , V. Radu , D. A. Simpson , A. Mogas Barcons , C. F. Adams , M. L. Mather

Quantum sensors provide unprecedented magnetic field detection sensitivities, enabling these to extend the common magnetometry range of applications and environments of operation. In this framework, many applications also require high…

Applied Physics · Physics 2023-05-02 Marc Jofre , Jordi Romeu , Luis Jofre-Roca

Diamond nanoparticles (nanodiamonds) can transport active drugs in cultured cells as well as in vivo. However, in the latter case, methods allowing to determine their bioavailability accurately are still lacking. Nanodiamond can be made…

Flow sensing is fundamental to both biological survival and technological innovation. Inspired by biological mechanoreceptors, artificial flow sensors detect subtle fluid motion using slender, viscous-driven structures. Among these,…

Fluid Dynamics · Physics 2025-11-17 Wei Sun , Wanyin Zheng , Xiangyu Wei , David A. Czaplewski , Ronald N. Miles , Jian Zhou

The nitrogen-vacancy (NV) center in diamond exists in different charge states with distinct photoluminescence properties, which are sensitive to the nanoscale electrochemical environment. Hence, the NV charge state is emerging as a powerful…

Mesoscale and Nanoscale Physics · Physics 2026-05-12 Patrick Voorhoeve , Hiroshi Abe , Takeshi Ohshima , Qiang Sun , Anita Quigley , Rob Kapsa , Nikolai Dontschuk , Philipp Reineck

During the past decade, interest has grown significantly in developing ultrasensitive widefield diamond magnetometry for various applications. Despite attempts to improve the adoption of conventional frame-based sensors, achieving high…

Instrumentation and Detectors · Physics 2023-06-27 Zhiyuan Du , Madhav Gupta , Feng Xu , Kai Zhang , Jiahua Zhang , Yan Zhou , Yiyao Liu , Zhenyu Wang , Jorg Wrachtrup , Ngai Wong , Can Li , Zhiqin Chu

Microdialysis is a well-established method for in vivo neurochemical measurements of small molecules, with implanted concentric-design probes offering minimized tissue damage and good temporal and spatial resolution. However, the large…

Quantitative Methods · Quantitative Biology 2021-09-10 Damon Vinciguerra , Margot Vigeant , Ewan C. McNay

Diamond has attracted great interest as a quantum technology platform thanks to its optically active nitrogen vacancy center (NV). The NV's ground state spin can be read out optically exhibiting long spin coherence times of about 1 ms even…

Quantum sensors based on the nitrogen-vacancy (NV) centre in diamond are rapidly advancing from scientific exploration towards the first generation of commercial applications. While significant progress has been made in developing suitable…

Cleaner analytic technique for quantifying compounds in dense suspension is needed for wastewater and environment analysis, chemical or bio-conversion process monitoring, biomedical diagnostics, food quality control among others. In this…

Soft Condensed Matter · Physics 2021-05-11 Jae Bem You , Detlef Lohse , Xuehua Zhang