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Related papers: Semiparametric fiducial inference for Cox models

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We consider the problem of estimating the distribution of time-to-event data that are subject to censoring and for which the event of interest might never occur, i.e., some subjects are cured. To model this kind of data in the presence of…

Statistics Theory · Mathematics 2018-06-05 François Portier , Ingrid Van Keilegom , Anouar El Ghouch

We propose a new class of multivariate survival models based on archimedean copulas with margins modeled by the Yang and Prentice (YP) model. The Ali-Mikhail-Haq (AMH), Clayton, Frank, Gumbel-Hougaard (GH), and Joe copulas are employed to…

Methodology · Statistics 2022-03-08 W. D. R. Miranda Filho , F. N. Demarqui

The penalized Cox proportional hazard model is a popular analytical approach for survival data with a large number of covariates. Such problems are especially challenging when covariates vary over follow-up time (i.e., the covariates are…

Methodology · Statistics 2021-06-10 Steve Cygu , Jonathan Dushoff , Benjamin M. Bolker

Fisher's fiducial argument is widely viewed as a failed version of Neyman's theory of confidence limits. But Fisher's goal -- Bayesian-like probabilistic uncertainty quantification without priors -- was more ambitious than Neyman's, and…

Statistics Theory · Mathematics 2023-12-25 Ryan Martin

Fisher's likelihood is widely used for statistical inference for fixed unknowns. This paper aims to extend two important likelihood-based methods, namely the maximum likelihood procedure for point estimation and the confidence procedure for…

Statistics Theory · Mathematics 2025-03-03 Hangbin Lee , Youngjo Lee

The Cox regression model is a popular model for analyzing the relationship between a covariate and a survival endpoint. The standard Cox model assumes a constant covariate effect across the entire covariate domain. However, in many…

Applications · Statistics 2019-09-02 Sarit Agami , David M. Zucker , Donna Spiegelman

The proportional hazards model has been extensively used in many fields such as biomedicine to estimate and perform statistical significance testing on the effects of covariates influencing the survival time of patients. The classical…

Statistics Theory · Mathematics 2026-01-16 Hanxuan Ye , Xianyang Zhang , Huijuan Zhou

We propose a general approach for training survival analysis models that minimizes a worst-case error across all subpopulations that are large enough (occurring with at least a user-specified minimum probability). This approach uses a…

Machine Learning · Statistics 2022-11-22 Shu Hu , George H. Chen

We address the problem of survival regression modelling with multivariate responses and nonlinear covariate effects. Our model extends the proportional hazards model by introducing several weakly-parametric elements: the marginal baseline…

Methodology · Statistics 2025-10-16 Na Lei , Mark A. Wolters , Wenqing He

Survival analysis, or time-to-event analysis, is an important and widespread problem in healthcare research. Medical research has traditionally relied on Cox models for survival analysis, due to their simplicity and interpretability. Cox…

Machine Learning · Computer Science 2023-10-25 Mike Van Ness , Tomas Bosschieter , Natasha Din , Andrew Ambrosy , Alexander Sandhu , Madeleine Udell

Proportional hazards (PH), proportional odds (PO) and accelerated failure time (AFT) models have been widely used to deal with survival data in different fields of knowledge. Despite their popularity, such models are not suitable to handle…

Methodology · Statistics 2019-10-08 Fabio N. Demarqui , Vinicius D. Mayrink

We propose a new fiducial Markov Chain Monte Carlo (MCMC) method for fitting parametric Gaussian models. We utilize the Cayley transform to decompose the parametric covariance matrix, which in turn allows us to formulate a general data…

Methodology · Statistics 2026-02-24 Hank Flury , Jan Hannig , Richard Smith

Tree-based priors for probability distributions are usually specified using a predetermined, data-independent collection of candidate recursive partitions of the sample space. To characterize an unknown target density in detail over the…

Methodology · Statistics 2025-04-14 Li Ma , Benedetta Bruni

In this paper we address the challenges posed by non-proportional hazards and informative censoring, offering a path toward more meaningful causal inference conclusions. We start from the marginal structural Cox model, which has been widely…

Methodology · Statistics 2023-11-15 Jiyu Luo , Denise Rava , Jelena Bradic , Ronghui Xu

We apply Gaussian process (GP) regression, which provides a powerful non-parametric probabilistic method of relating inputs to outputs, to survival data consisting of time-to-event and covariate measurements. In this context, the covariates…

Statistics Theory · Mathematics 2014-09-08 James E. Barrett , Anthony C. C. Coolen

Generalized Fiducial Inference (GFI) is motivated by R.A. Fisher's approach of obtaining posterior-like distributions when there is no prior information available for the unknown parameter. Without the use of Bayes' theorem GFI proposes a…

Statistics Theory · Mathematics 2016-08-26 Abhishek Pal Majumder , Jan Hannig

The Cox proportional hazards model is often used to analyze data from Randomized Controlled Trials (RCT) with time-to-event outcomes. Random survival forest (RSF) is a machine-learning algorithm known for its high predictive performance. We…

Machine Learning · Statistics 2025-05-28 Ricarda Graf , Susan Todd , M. Fazil Baksh

We revisit Cox's proportional hazard models and LASSO in the aim of improving feature selection in survival analysis. Unlike traditional methods relying on cross-validation or BIC, the penalty parameter $\lambda$ is directly tuned for…

Machine Learning · Statistics 2025-10-23 Maxime van Cutsem , Sylvain Sardy

In this paper, we consider a discrete-time stochastic SIR model, where the transmission rate and the true number of infectious individuals are random and unobservable. An advantage of this model is that it permits us to account for random…

Physics and Society · Physics 2024-01-30 Katia Colaneri , Camilla Damian , Rüdiger Frey

The robust Poisson method is becoming increasingly popular when estimating the association of exposures with a binary outcome. Unlike the logistic regression model, the robust Poisson method yields results that can be interpreted as risk or…

Methodology · Statistics 2022-09-14 Denis Talbot , Miceline Mésidor , Yohann Chiu , Marc Simard , Caroline Sirois
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