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This paper presents an efficient methodology for the robust optimisation of Continuous Flow Polymerase Chain Reaction (CFPCR) devices. It enables the effects of uncertainties in device geometry, due to manufacturing tolerances, on the…

Computational Engineering, Finance, and Science · Computer Science 2021-06-02 Yongxing Wang , Hazim A. Hamad , Jochen Voss , Harvey M. Thompson

Entangled atomic states, such as spin squeezed states, represent a promising resource for a new generation of quantum sensors and atomic clocks. We demonstrate that optimal control techniques can be used to substantially enhance the degree…

Quantum Physics · Physics 2016-02-03 T. Pichler , T. Caneva , S. Montangero , M. D. Lukin , T. Calarco

Inverse optimal control (IOC) is a promising paradigm for learning and mimicking optimal control strategies from capable demonstrators, or gaining a deeper understanding of their intentions, by estimating an unknown objective function from…

Systems and Control · Electrical Eng. & Systems 2025-08-28 Rahel Rickenbach , Amon Lahr , Melanie N. Zeilinger

We formulate and analyse an optimal control problem for the coagulation-fragmentation equation, where a scalar, time-dependent control modulates the coagulation rate by multiplying the coagulation kernel. The objective functional consists…

Optimization and Control · Mathematics 2026-04-16 Enrico Sartor

The performance of sequences of designed pulses of finite length $\tau$ is analyzed for a bath of spins and it is compared with that of sequences of ideal, instantaneous pulses. The degree of the design of the pulse strongly affects the…

Quantum Physics · Physics 2015-05-19 S. Pasini , P. Karbach , G. S. Uhrig

Precision pulsar timing requires optimization against measurement errors and astrophysical variance from the neutron stars themselves and the interstellar medium. We investigate optimization of arrival time precision as a function of radio…

High Energy Astrophysical Phenomena · Physics 2018-06-28 M. T. Lam , M. A. McLaughlin , J. M. Cordes , S. Chatterjee , T. J. W. Lazio

Intravascular polarimetry with catheter-based polarization-sensitive optical coherence tomography (PS-OCT) complements the high-resolution structural tomograms of OCT with morphological contrast available through polarimetry. Its clinical…

Laser frequency fluctuation and atomic thermal motion can lead to errors in pulse duration and detuning in cold atom interferometry, thereby reducing measurement stability and fringe contrast. To address this issue, we investigate the use…

Atomic Physics · Physics 2025-09-09 Yujuan Liu , Ziwen Song , Tingting Lin , Biao Tang , Aoxing Hao

Achieving intrinsic optical chirality requires breaking all mirror symmetries of an object, and maximum chirality, which allows interaction with only one helicity of light, is particularly promising for applications such as chiral sensing,…

Optics · Physics 2025-02-28 Jiaqi Niu , Jingquan Liu , Bin Yang

Bayesian Optimal Experimental Design (BOED) is a powerful tool to reduce the cost of running a sequence of experiments. When based on the Expected Information Gain (EIG), design optimization corresponds to the maximization of some…

Machine Learning · Statistics 2025-03-14 Jacopo Iollo , Christophe Heinkelé , Pierre Alliez , Florence Forbes

We show how additional constraints, restricting the spectrum of the optimized pulse or confining the system dynamics, can be used to steer optimization in quantum control towards distinct solutions. Our examples are multi-photon excitation…

Quantum Physics · Physics 2013-11-18 José P. Palao , Daniel M. Reich , Christiane P. Koch

A novel chirped pulse control scheme is presented based on Coherent Anti-Stokes Raman Spectroscopy (C-CARS) aiming at maximizing the vibrational coherence in atoms and molecules. The scheme utilizes chirping of the three incoming pulses,…

Quantum Physics · Physics 2023-09-06 Jabir Chathanathil , Svetlana A. Malinovskaya

The onset of rheumatic diseases such as rheumatoid arthritis is typically subclinical, which results in challenging early detection of the disease. However, characteristic changes in the anatomy can be detected using imaging techniques such…

Bi-static sensing is crucial for exploring the potential of networked sensing capabilities in integrated sensing and communications (ISAC). However, it suffers from the challenging clock asynchronism issue. CSI ratio-based sensing is an…

Information Theory · Computer Science 2024-01-18 Yanmo Hu , Kai Wu , J. Andrew Zhang , Weibo Deng , Y. Jay Guo

Finding control fields (pulse sequences) that can compensate for the dispersion in the parameters governing the evolution of a quantum system is an important problem in coherent spectroscopy and quantum information processing. The use of…

Quantum Physics · Physics 2015-06-04 Philip Owrutsky , Navin Khaneja

We present a novel particle filtering framework for continuous-time dynamical systems with continuous-time measurements. Our approach is based on the duality between estimation and optimal control, which allows reformulating the estimation…

Optimization and Control · Mathematics 2021-10-08 Qinsheng Zhang , Amirhossein Taghvaei , Yongxin Chen

Electrical impedance tomography (EIT) is a noninvasive imaging method whereby electrical measurements on the boundary of a conductive medium (the data) are taken according to a prescribed protocol set and inverted to map the internal…

The measurement of electron cloud densities in particle accelerators using microwaves has proven to be an effective, non-invasive and inexpensive method. So far the experimental schemes have used continuous waves. This has either been in…

Accelerator Physics · Physics 2015-11-06 Kiran G. Sonnad

Purpose: Universal Pulses (UPs) are excitation pulses that reduce the flip angle inhomogeneity in high field MRI systems without subject-specific optimization, originally developed for parallel transmit (PTX) systems at 7T. We investigated…

Extrusion-based 3D printing of cementitious materials enables fabrication of complex structures, however it is highly sensitive to disturbances, material property variations, and process uncertainties that decrease flow stability and…

Systems and Control · Electrical Eng. & Systems 2026-03-23 Mandana Mohammadi Looey , Amrita Basak , Satadru Dey