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Transjugular intrahepatic portosystemic shunt (TIPS) is an established procedure for portal hypertension, but provides variable survival outcomes and frequent overt hepatic encephalopathy (OHE), indicating the necessity of accurate…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Junhao Dong , Dejia Liu , Ruiqi Ding , Zongxing Chen , Yingjie Huang , Zhu Meng , Jianbo Zhao , Zhicheng Zhao , Fei Su

Unpacking and comprehending how black-box machine learning algorithms make decisions has been a persistent challenge for researchers and end-users. Explaining time-series predictive models is useful for clinical applications with high…

Machine Learning · Computer Science 2023-05-09 Amin Nayebi , Sindhu Tipirneni , Chandan K Reddy , Brandon Foreman , Vignesh Subbian

Accurate prediction of postoperative complications can inform shared decisions regarding prognosis, preoperative risk-reduction, and postoperative resource use. We hypothesized that multi-task deep learning models would outperform random…

Postoperative complications pose a significant challenge in the healthcare industry, resulting in elevated healthcare expenses and prolonged hospital stays, and in rare instances, patient mortality. To improve patient outcomes and reduce…

Machine Learning · Computer Science 2023-06-07 Reza Shirkavand , Fei Zhang , Heng Huang

Segmentation is the identification of anatomical regions of interest, such as organs, tissue, and lesions, serving as a fundamental task in computer-aided diagnosis in medical imaging. Although deep learning models have achieved remarkable…

Image and Video Processing · Electrical Eng. & Systems 2025-12-09 Tianyi Ren , Daniel Low , Pittra Jaengprajak , Juampablo Heras Rivera , Jacob Ruzevick , Mehmet Kurt

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei

To test the hypothesis that accuracy, discrimination, and precision in predicting postoperative complications improve when using both preoperative and intraoperative data input features versus preoperative data alone. Models that predict…

Predicting stroke risk is a complex challenge that can be enhanced by integrating diverse clinically available data modalities. This study introduces a self-supervised multimodal framework that combines 3D brain imaging, clinical data, and…

Computer Vision and Pattern Recognition · Computer Science 2025-07-09 Camille Delgrange , Olga Demler , Samia Mora , Bjoern Menze , Ezequiel de la Rosa , Neda Davoudi

Shapley values have become one of the most popular feature attribution explanation methods. However, most prior work has focused on post-hoc Shapley explanations, which can be computationally demanding due to its exponential time complexity…

Machine Learning · Computer Science 2021-04-07 Rui Wang , Xiaoqian Wang , David I. Inouye

The majority of biomedical studies use limited datasets that may not generalize over large heterogeneous datasets that have been collected over several decades. The current paper develops and validates several multimodal models that can…

Shapley values has established itself as one of the most appropriate and theoretically sound frameworks for explaining predictions from complex machine learning models. The popularity of Shapley values in the explanation setting is probably…

Machine Learning · Statistics 2021-06-24 Martin Jullum , Annabelle Redelmeier , Kjersti Aas

Shapley values have seen widespread use in machine learning as a way to explain model predictions and estimate the importance of covariates. Accurately explaining models is critical in real-world models to both aid in decision making and to…

Machine Learning · Statistics 2024-08-19 Daniel de Marchi , Michael Kosorok , Scott de Marchi

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

Hip fractures are a leading cause of death and disability among older adults. Hip fractures are also the most commonly missed diagnosis on pelvic radiographs. Computer-Aided Diagnosis (CAD) algorithms have shown promise for helping…

Hospitalization of patients is one of the major factors for high wound care costs. Most patients do not acquire a wound which needs immediate hospitalization. However, due to factors such as delay in treatment, patient's non-compliance or…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Subba Reddy Oota , Vijay Rowtula , Shahid Mohammed , Jeffrey Galitz , Minghsun Liu , Manish Gupta

In this paper, we propose ShapTST, a framework that enables time-series transformers to efficiently generate Shapley-value-based explanations alongside predictions in a single forward pass. Shapley values are widely used to evaluate the…

Machine Learning · Computer Science 2025-01-28 Qisen Cheng , Jinming Xing , Chang Xue , Xiaoran Yang

Hyperparameter optimization (HPO) is a crucial step in achieving strong predictive performance. Yet, the impact of individual hyperparameters on model generalization is highly context-dependent, prohibiting a one-size-fits-all solution and…

Machine Learning · Computer Science 2025-11-11 Marcel Wever , Maximilian Muschalik , Fabian Fumagalli , Marius Lindauer

The problem of explaining the behavior of deep neural networks has recently gained a lot of attention. While several attribution methods have been proposed, most come without strong theoretical foundations, which raises questions about…

Machine Learning · Computer Science 2019-06-24 Marco Ancona , Cengiz Öztireli , Markus Gross

In this paper we introduce a metric aimed at helping machine learning practitioners quickly summarize and communicate the overall importance of each feature in any black-box machine learning prediction model. Our proposed metric, based on a…

Methodology · Statistics 2019-08-27 Nickalus Redell

As opaque black-box predictive models become more prevalent, the need to develop interpretations for these models is of great interest. The concept of variable importance and Shapley values are interpretability measures that applies to any…

Machine Learning · Statistics 2025-03-10 Zexuan Sun , Garvesh Raskutti