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Large Language Models (LLMs) have demonstrated impressive capabilities across natural language processing tasks. However, their application to specialized domains such as medicine and biology requires further optimization to ensure factual…

Computation and Language · Computer Science 2025-02-06 Seonok Kim

This study presents a novel two-stage Retrieve-Rank system for automated ICD-10-CM medical coding, comparing its performance against a Vanilla Large Language Model (LLM) approach. Evaluating both systems on a dataset of 100 single-term…

Information Retrieval · Computer Science 2024-07-19 Keith Kwan

Recent advancements in mixed-modal generative have opened new avenues for developing unified biomedical assistants capable of analyzing biomedical images, answering complex questions about them, and generating multimodal patient reports.…

Artificial Intelligence · Computer Science 2025-04-24 Hritik Bansal , Daniel Israel , Siyan Zhao , Shufan Li , Tung Nguyen , Aditya Grover

Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…

Computer Vision and Pattern Recognition · Computer Science 2025-07-14 Inye Na , Nejung Rue , Jiwon Chung , Hyunjin Park

Dense retrievers have made significant strides in text retrieval and open-domain question answering. However, most of these achievements have relied heavily on extensive human-annotated supervision. In this study, we aim to develop…

Computation and Language · Computer Science 2024-10-31 Rui Meng , Ye Liu , Semih Yavuz , Divyansh Agarwal , Lifu Tu , Ning Yu , Jianguo Zhang , Meghana Bhat , Yingbo Zhou

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Computation and Language · Computer Science 2021-12-16 Robert Tinn , Hao Cheng , Yu Gu , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Recent advancements in large language models (LLMs) like ChatGPT and LLaMA show promise in medical applications, yet challenges remain in medical language comprehension. This study presents Me-LLaMA, a new medical LLM family based on…

Retrieval-augmented generation (RAG) is a common way to ground language models in external documents and up-to-date information. Classical retrieval systems relied on lexical methods such as BM25, which rank documents by term overlap with…

Computation and Language · Computer Science 2026-03-05 Martin Asenov , Kenza Benkirane , Dan Goldwater , Aneiss Ghodsi

Encoder-based transformer models are central to biomedical and clinical Natural Language Processing (NLP), as their bidirectional self-attention makes them well-suited for efficiently extracting structured information from unstructured text…

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

Computation and Language · Computer Science 2023-08-21 Pavlova Vera , Mohammed Makhlouf

In this study, we uncover the unexpected efficacy of residual-based large language models (LLMs) as part of encoders for biomedical imaging tasks, a domain traditionally devoid of language or textual data. The approach diverges from…

Computer Vision and Pattern Recognition · Computer Science 2024-04-01 Zhixin Lai , Jing Wu , Suiyao Chen , Yucheng Zhou , Naira Hovakimyan

Given the dominance of dense retrievers that do not generalize well beyond their training dataset distributions, domain-specific test sets are essential in evaluating retrieval. There are few test datasets for retrieval systems intended for…

Information Retrieval · Computer Science 2025-07-01 Nadia Athar Sheikh , Daniel Buades Marcos , Anne-Laure Jousse , Akintunde Oladipo , Olivier Rousseau , Jimmy Lin

State-of-the-art performance on language understanding tasks is now achieved with increasingly large networks; the current record holder has billions of parameters. Given a language model pre-trained on massive unlabeled text corpora, only…

Computation and Language · Computer Science 2020-04-30 Evani Radiya-Dixit , Xin Wang

In this paper we introduce RE-tune, a novel approach for fine-tuning pre-trained Multimodal Biomedical Vision-Language models (VLMs) in Incremental Learning scenarios for multi-label chest disease diagnosis. RE-tune freezes the backbones…

Artificial Intelligence · Computer Science 2024-10-24 Marco Mistretta , Andrew D. Bagdanov

Background: The radiation oncology clinical practice involves many steps relying on the dynamic interplay of abundant text data. Large language models have displayed remarkable capabilities in processing complex text information. But their…

With the burgeoning development in the realm of large language models (LLMs), the demand for efficient incremental training tailored to specific industries and domains continues to increase. Currently, the predominantly employed frameworks…

Computation and Language · Computer Science 2023-08-22 Yixuan Weng , Zhiqi Wang , Huanxuan Liao , Shizhu He , Shengping Liu , Kang Liu , Jun Zhao

Scientific knowledge discovery increasingly relies on large language models, yet many existing scholarly assistants depend on proprietary systems with tens or hundreds of billions of parameters. Such reliance limits reproducibility and…

Information Retrieval · Computer Science 2026-04-23 Florian Kelber , Matthias Jobst , Yuni Susanti , Michael Färber

With hundreds of thousands of language models available on Huggingface today, efficiently evaluating and utilizing these models across various downstream, tasks has become increasingly critical. Many existing methods repeatedly learn…

Computation and Language · Computer Science 2024-10-18 Richard Zhuang , Tianhao Wu , Zhaojin Wen , Andrew Li , Jiantao Jiao , Kannan Ramchandran

We consider the large-scale query-document retrieval problem: given a query (e.g., a question), return the set of relevant documents (e.g., paragraphs containing the answer) from a large document corpus. This problem is often solved in two…

Machine Learning · Computer Science 2020-02-11 Wei-Cheng Chang , Felix X. Yu , Yin-Wen Chang , Yiming Yang , Sanjiv Kumar

The massive scale and growth of textual biomedical data have made its indexing and classification increasingly important. However, existing research on this topic mainly utilized convolutional and recurrent neural networks, which generally…

Computation and Language · Computer Science 2022-03-08 Bruce Nguyen , Shaoxiong Ji