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Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) are key diagnostic tools for clinical evaluation and management of retinal diseases. Compared to traditional OCT, OCTA provides richer microvascular…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Renzhi Tian , Jinjie Wang , Wei Yang , Weizhen Li , Haoran Chen , Yiran Zhu , Chengchang Pan , Honggang Qi

Optical coherence tomography (OCT) is a medical imaging modality that allows us to probe deeper substructures of skin. The state-of-the-art wound care prediction and monitoring methods are based on visual evaluation and focus on surface…

Image and Video Processing · Electrical Eng. & Systems 2023-06-05 Prashant Kumar , Swatantra Dhara , Ayan Gope , Jyotirmoy Chatterjee , Subhamoy Mandal

Optical Coherence Tomography (OCT) has become one of the most used imaging modality in ophthalmology. It provides high-resolution, non-invasive visualization of retinal microarchitecture. The automated analysis of OCT images through…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Hedi Tabia , Désiré Sidibé , Nawres Khlifa , Ahmed Tabia , Ines Rahmany , Noura Aboudi , Zainab Haddad , Hajer Khachnaoui , Hsouna Zgolli

Various deep learning models have been developed to segment anatomical structures from medical images, but they typically have poor performance when tested on another target domain with different data distribution. Recently, unsupervised…

Image and Video Processing · Electrical Eng. & Systems 2022-01-21 Linkai Peng , Li Lin , Pujin Cheng , Ziqi Huang , Xiaoying Tang

This study is to demonstrate deep learning for automated artery-vein (AV) classification in optical coherence tomography angiography (OCTA). The AV-Net, a fully convolutional network (FCN) based on modified U-shaped CNN architecture,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Minhaj Alam , David Le , Taeyoon Son , Jennifer I. Lim , Xincheng Yao

Strong speckle noise is inherent to optical coherence tomography (OCT) imaging and represents a significant obstacle for accurate quantitative analysis of retinal structures which is key for advances in clinical diagnosis and monitoring of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Shijie Li , Palaiologos Alexopoulos , Anse Vellappally , Ronald Zambrano , Wollstein Gadi , Guido Gerig

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging technique that allows visualizations of vasculature and foveal avascular zone (FAZ) across retinal layers. Clinical researches suggest that the morphology and…

Image and Video Processing · Electrical Eng. & Systems 2021-07-14 Li Lin , Zhonghua Wang , Jiewei Wu , Yijin Huang , Junyan Lyu , Pujin Cheng , Jiong Wu , Xiaoying Tang

Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. Due to the underlying physics, OCT images usually suffer from a granular…

Computer Vision and Pattern Recognition · Computer Science 2015-02-10 Ahmadreza Baghaie , Roshan M. D'souza , Zeyun Yu

Accurately segmenting fluid in 3D optical coherence tomography (OCT) images is critical for detecting eye diseases but remains challenging. Traditional autoencoder-based methods struggle with resolution loss and information recovery. While…

Image and Video Processing · Electrical Eng. & Systems 2025-01-06 Khondker Fariha Hossain , Sharif Amit Kamran , Alireza Tavakkoli , George Bebis , Sal Baker

Medical image segmentation often requires segmenting multiple elliptical objects on a single image. This includes, among other tasks, segmenting vessels such as the aorta in axial CTA slices. In this paper, we present a general approach to…

Image and Video Processing · Electrical Eng. & Systems 2022-06-22 Marin Benčević , Marija Habijan , Irena Galić , Danilo Babin

Recent advancements in medical image analysis have led to the development of highly specialized models tailored to specific clinical tasks. These models have demonstrated exceptional performance and remain a crucial research direction. Yet,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Alessio Negrini , Simon Reiß

Multiple-surface segmentation in Optical Coherence Tomography (OCT) images is a challenge problem, further complicated by the frequent presence of weak image boundaries. Recently, many deep learning (DL) based methods have been developed…

Image and Video Processing · Electrical Eng. & Systems 2022-10-13 Hui Xie , Weiyu Xu , Xiaodong Wu

Recent studies suggest that early stages of diabetic retinopathy (DR) can be diagnosed by monitoring vascular changes in the deep vascular complex. In this work, we investigate a novel method for automated DR grading based on optical…

Image and Video Processing · Electrical Eng. & Systems 2022-12-22 Linus Kreitner , Ivan Ezhov , Daniel Rueckert , Johannes C. Paetzold , Martin J. Menten

Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

Automated segmentation of retinal optical coherence tomography (OCT) images has become an important recent direction in machine learning for medical applications. We hypothesize that the anatomic structure of layers and their high-frequency…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Azade Farshad , Yousef Yeganeh , Peter Gehlbach , Nassir Navab

Existing deep learning frameworks for Optical Coherence Tomography Angiography (OCTA) vessel segmentation are largely derived from the U-Net architecture, which serves as the foundation for most current designs. However, most of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Tuopusen Huang , Ding Ma , Xiangqian Wu

In OCT angiography (OCTA), decorrelation computation has been widely used as a local motion index to identify dynamic flow from static tissues, but its dependence on SNR severely degrades the vascular visibility, particularly in low- SNR…

Medical Physics · Physics 2019-04-16 Luzhe Huang , Yiming Fu , Ruixiang Chen , Shanshan Yang , Haixia Qiu , Xining Wu , Shiyong Zhao , Ying Gu , Peng Li

The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

Image and Video Processing · Electrical Eng. & Systems 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

The development of artificial intelligence models for macular edema (ME) analy-sis always relies on expert-annotated pixel-level image datasets which are expen-sive to collect prospectively. While anomaly-detection-based weakly-supervised…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Yuhui Tao , Yizhe Zhang , Qiang Chen

As a non-invasive imaging modality, optical coherence tomography (OCT) can provide micrometer-resolution 3D images of retinal structures. Therefore it is commonly used in the diagnosis of retinal diseases associated with edema in and under…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Morgan Heisler , Sieun Lee , Gavin Ding , Marinko V. Sarunic , Mirza Faisal Beg