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Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by…

Human-Computer Interaction · Computer Science 2026-03-31 Peng Kuai , Yukun Yang , Shaolun Ruan , Junchi Xu , Yanjie Zhang , Lin Zhang , Min Zhu , Rui Sheng

Deep Research (DR) agents extend Large Language Models (LLMs) beyond parametric knowledge by autonomously retrieving and synthesizing evidence from large web corpora into long-form reports, enabling a long-horizon agentic paradigm. However,…

Artificial Intelligence · Computer Science 2026-02-04 Haohao Luo , Zexi Li , Yuexiang Xie , Wenhao Zhang , Yaliang Li , Ying Shen

Significantly simplifying the creation of optimization models for real-world business problems has long been a major goal in applying mathematical optimization more widely to important business and societal decisions. The recent…

Artificial Intelligence · Computer Science 2024-02-27 Segev Wasserkrug , Leonard Boussioux , Dick den Hertog , Farzaneh Mirzazadeh , Ilker Birbil , Jannis Kurtz , Donato Maragno

Despite the critical threat posed by software security vulnerabilities, reports are often incomplete, lacking the proof-of-vulnerability (PoV) tests needed to validate fixes and prevent regressions. These tests are crucial not only for…

Software Engineering · Computer Science 2025-07-22 Vikram Nitin , Baishakhi Ray , Roshanak Zilouchian Moghaddam

Embodied agents tasked with complex scenarios, whether in real or simulated environments, rely heavily on robust planning capabilities. When instructions are formulated in natural language, large language models (LLMs) equipped with…

Recent advancements in large language models (LLMs) have enabled LLM-based agents to successfully tackle interactive planning tasks. However, despite their successes, existing approaches often suffer from planning hallucinations and require…

Computation and Language · Computer Science 2025-09-11 Weimin Xiong , Yifan Song , Qingxiu Dong , Bingchan Zhao , Feifan Song , Xun Wang , Sujian Li

Open-sourced Large Language Models (LLMs) have achieved great success in various NLP tasks, however, they are still far inferior to API-based models when acting as agents. How to integrate agent ability into general LLMs becomes a crucial…

Computation and Language · Computer Science 2024-03-20 Zehui Chen , Kuikun Liu , Qiuchen Wang , Wenwei Zhang , Jiangning Liu , Dahua Lin , Kai Chen , Feng Zhao

Large language models (LLMs) are revolutionizing education, with LLM-based agents playing a key role in simulating student behavior. A major challenge in student simulation is modeling the diverse learning patterns of students at various…

Machine Learning · Computer Science 2025-08-12 Tao Wu , Jingyuan Chen , Wang Lin , Mengze Li , Yumeng Zhu , Ang Li , Kun Kuang , Fei Wu

The pursuit of human-level artificial intelligence (AI) has significantly advanced the development of autonomous agents and Large Language Models (LLMs). LLMs are now widely utilized as decision-making agents for their ability to interpret…

The integration of workflows with large language models (LLMs) enables LLM-based agents to execute predefined procedures, enhancing automation in real-world applications. Traditional rule-based methods tend to limit the inherent flexibility…

Artificial Intelligence · Computer Science 2025-02-21 Yuchen Shi , Siqi Cai , Zihan Xu , Yuei Qin , Gang Li , Hang Shao , Jiawei Chen , Deqing Yang , Ke Li , Xing Sun

As the strength of Large Language Models (LLMs) has grown over recent years, so too has interest in their use as the underlying models for autonomous agents. Although LLMs demonstrate emergent abilities and broad expertise across natural…

Artificial Intelligence · Computer Science 2024-12-06 Chris Sypherd , Vaishak Belle

Successful application of large language models (LLMs) to robotic planning and execution may pave the way to automate numerous real-world tasks. Promising recent research has been conducted showing that the knowledge contained in LLMs can…

Robotics · Computer Science 2024-07-23 Ateeq Sharfuddin , Travis Breaux

Large language models (LLMs) excel at complex reasoning tasks but remain computationally expensive, limiting their practical deployment. To address this, recent works have focused on distilling reasoning capabilities into smaller language…

Computation and Language · Computer Science 2025-11-06 Minki Kang , Jongwon Jeong , Seanie Lee , Jaewoong Cho , Sung Ju Hwang

While recent AI-for-math has made strides in pure mathematics, areas of applied mathematics, particularly PDEs, remain underexplored despite their significant real-world applications. We present PDE-Controller, a framework that enables…

Machine Learning · Computer Science 2025-06-12 Mauricio Soroco , Jialin Song , Mengzhou Xia , Kye Emond , Weiran Sun , Wuyang Chen

Planning represents a fundamental capability of intelligent agents, requiring comprehensive environmental understanding, rigorous logical reasoning, and effective sequential decision-making. While Large Language Models (LLMs) have…

Artificial Intelligence · Computer Science 2025-05-27 Pengfei Cao , Tianyi Men , Wencan Liu , Jingwen Zhang , Xuzhao Li , Xixun Lin , Dianbo Sui , Yanan Cao , Kang Liu , Jun Zhao

Although planning is a crucial component of the autonomous driving stack, researchers have yet to develop robust planning algorithms that are capable of safely handling the diverse range of possible driving scenarios. Learning-based…

Artificial Intelligence · Computer Science 2024-01-02 S P Sharan , Francesco Pittaluga , Vijay Kumar B G , Manmohan Chandraker

Large Language Models (LLMs) have achieved significant advancements, but the increasing complexity of tasks and higher performance demands highlight the need for continuous improvement. Some approaches utilize synthetic data generated by…

Artificial Intelligence · Computer Science 2025-06-23 Haokun Zhao , Jinyi Han , Jiaqing Liang , Yanghua Xiao , Xiaojun Meng , Jiansheng Wei

While Large Language Models (LLMs) have demonstrated significant promise as agents in interactive tasks, their substantial computational requirements and restricted number of calls constrain their practical utility, especially in…

Machine Learning · Computer Science 2024-05-07 Maryam Hashemzadeh , Elias Stengel-Eskin , Sarath Chandar , Marc-Alexandre Cote

Foundation models are becoming valuable tools in medicine. Yet despite their promise, the best way to leverage Large Language Models (LLMs) in complex medical tasks remains an open question. We introduce a novel multi-agent framework, named…

Computation and Language · Computer Science 2024-10-31 Yubin Kim , Chanwoo Park , Hyewon Jeong , Yik Siu Chan , Xuhai Xu , Daniel McDuff , Hyeonhoon Lee , Marzyeh Ghassemi , Cynthia Breazeal , Hae Won Park

Large Language Model (LLM) agents have demonstrated remarkable generalization capabilities across multi-domain tasks. Existing agent tuning approaches typically employ supervised finetuning on entire expert trajectories. However,…

Computation and Language · Computer Science 2025-06-06 Zhixun Chen , Ming Li , Yuxuan Huang , Yali Du , Meng Fang , Tianyi Zhou
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