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The "AI Scientist" paradigm is transforming scientific research by automating key stages of the research process, from idea generation to scholarly writing. This shift is expected to accelerate discovery and expand the scope of scientific…

Human-Computer Interaction · Computer Science 2026-02-05 Keyu Zhao , Fengli Xu , Yong Li , Tie-Yan Liu

One of the grand challenges of artificial general intelligence is developing agents capable of conducting scientific research and discovering new knowledge. While frontier models have already been used as aides to human scientists, e.g. for…

Artificial Intelligence · Computer Science 2024-09-04 Chris Lu , Cong Lu , Robert Tjarko Lange , Jakob Foerster , Jeff Clune , David Ha

This paper introduces Agent-Based Auto Research, a structured multi-agent framework designed to automate, coordinate, and optimize the full lifecycle of scientific research. Leveraging the capabilities of large language models (LLMs) and…

Autonomous scientific discovery with large language model (LLM)-based agents has recently made substantial progress, demonstrating the ability to automate end-to-end research workflows. However, existing systems largely rely on…

Computational Engineering, Finance, and Science · Computer Science 2026-01-29 Tengyue Xu , Zhuoyang Qian , Gaoge Liu , Li Ling , Zhentao Zhang , Biao Wu , Shuo Zhang , Ke Lu , Wei Shi , Ziqi Wang , Zheng Feng , Yan Luo , Shu Xu , Yongjin Chen , Zhibo Feng , Zhuo Chen , Bruce Yuan , Harry Wang , Kris Chen

With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are…

Autonomous research systems capable of generating complete scientific manuscripts have advanced rapidly, yet robust and realistic evaluation frameworks have failed to keep pace. To bridge this gap, we introduce MLReplicate, an end-to-end…

Machine Learning · Computer Science 2026-05-19 Sasi Kiran Gaddipati , Diyana Muhammed , Farhana Keya , Gollam Rabby , Sören Auer

Collaboration is the defining mode of modern science, yet its core mechanism -- feedback -- remains hard to observe, difficult to scale, and unequally distributed. Here we test whether large language models (LLMs) can contribute to this…

Physics and Society · Physics 2026-05-26 Binglu Wang , Weixin Liang , Jiahui Xue , Yuhui Zhang , Hancheng Cao , Dashun Wang , Yian Yin

Autonomous machine learning research has gained significant attention recently. We present MLR-COPILOT, an autonomous Machine Learning Research framework powered by large language model agents. The system is designed to enhance ML research…

Artificial Intelligence · Computer Science 2025-11-18 Ruochen Li , Teerth Patel , Qingyun Wang , Xinya Du

The rapid integration of Large Language Models (LLMs) into scientific writing fundamentally challenges traditional definitions of authorship, responsibility, and scientific integrity. As researchers transition from using computers as…

Computational Physics · Physics 2026-04-07 Yi Zhou

We report a case study of four end-to-end attempts to autonomously generate ML research papers using a pipeline of six LLM agents mapped to stages of the scientific workflow. Of these four, three attempts failed during implementation or…

Machine Learning · Computer Science 2026-01-08 Dhruv Trehan , Paras Chopra

Large language models (LLMs) offer significant potential to accelerate systematic literature reviews (SLRs), yet current approaches often rely on brittle, manually crafted prompts that compromise reliability and reproducibility. This…

Computation and Language · Computer Science 2025-09-03 Teo Susnjak

Imagine decision-makers uploading data and, within minutes, receiving clear, actionable insights delivered straight to their fingertips. That is the promise of the AI Data Scientist, an autonomous Agent powered by large language models…

Artificial Intelligence · Computer Science 2025-08-26 Farkhad Akimov , Munachiso Samuel Nwadike , Zangir Iklassov , Martin Takáč

The rise of powerful large language models (LLMs) brings about tremendous opportunities for innovation but also looming risks for individuals and society at large. We have reached a pivotal moment for ensuring that LLMs and LLM-infused…

Human-Computer Interaction · Computer Science 2023-08-09 Q. Vera Liao , Jennifer Wortman Vaughan

Artificial intelligence (AI) models trained on published scientific findings have been used to invent valuable materials and targeted therapies, but they typically ignore the human scientists who continually alter the landscape of…

Artificial Intelligence · Computer Science 2023-06-05 Jamshid Sourati , James Evans

Artificial intelligence (AI) tools are being incorporated into scientific research workflows with the potential to enhance efficiency in tasks such as document analysis, question answering (Q&A), and literature search. However, system…

Artificial Intelligence · Computer Science 2026-05-13 Anthea Dathe , Kiran Hoffmann , Aline Mangold

Rapid development of artificial intelligence has drastically accelerated the development of scientific discovery. Trained with large-scale observation data, deep neural networks extract the underlying patterns in an end-to-end manner and…

Machine Learning · Computer Science 2024-11-26 Zijun Liu , Kaiming Liu , Yiqi Zhu , Xuanyu Lei , Zonghan Yang , Zhenhe Zhang , Peng Li , Yang Liu

Large language models (LLMs) have enabled agentic AI systems for scientific discovery, but most approaches remain limited to textbased reasoning without automated experimental verification. We propose MIND, an LLM-driven framework for…

Multiagent Systems · Computer Science 2026-04-16 Geonhee Ahn , Donghyun Lee , Hayoung Doo , Jonggeol Na , Hyunsoo Cho , Sookyung Kim

Many promising-looking ideas in AI research fail to deliver, but their validation takes substantial human labor and compute. Predicting an idea's chance of success is thus crucial for accelerating empirical AI research, a skill that even…

Artificial Intelligence · Computer Science 2025-06-03 Jiaxin Wen , Chenglei Si , Yueh-han Chen , He He , Shi Feng

The rapid evolution of artificial intelligence, particularly large language models, presents unprecedented opportunities for materials science research. We proposed and developed an AI materials scientist named MatPilot, which has shown…

Physics and Society · Physics 2024-11-14 Ziqi Ni , Yahao Li , Kaijia Hu , Kunyuan Han , Ming Xu , Xingyu Chen , Fengqi Liu , Yicong Ye , Shuxin Bai

Human-AI interaction researchers face an overwhelming challenge: synthesizing insights from thousands of empirical studies to understand how AI impacts people and inform effective design. Existing approach for literature reviews cluster…

Human-Computer Interaction · Computer Science 2025-10-01 Chayapatr Archiwaranguprok , Awu Chen , Sheer Karny , Hiroshi Ishii , Pattie Maes , Pat Pataranutaporn