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The dynamics of populations is frequently subject to intrinsic noise. At the same time unknown interaction networks or rate constants can present quenched uncertainty. Existing approaches often involve repeated sampling of the quenched…

Populations and Evolution · Quantitative Biology 2016-06-14 Tobias Galla

Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseases across biological systems and scales. Although the field…

Neural field models are commonly used to describe wave propagation and bump attractors at a tissue level in the brain. Although motivated by biology, these models are phenomenological in nature. They are built on the assumption that the…

Neurons and Cognition · Quantitative Biology 2019-01-16 Áine Byrne , Daniele Avitabile , Stephen Coombes

Understanding the patterns and processes of diversification of life in the planet is a key challenge of science. The Tree of Life represents such diversification processes through the evolutionary relationships among the different taxa, and…

Populations and Evolution · Quantitative Biology 2011-06-16 E. Alejandro Herrada , Claudio J. Tessone , Konstantin Klemm , Victor M. Eguiluz , Emilio Hernandez-Garcia , Carlos M. Duarte

Bayesian inference methods rely on numerical algorithms for both model selection and parameter inference. In general, these algorithms require a high computational effort to yield reliable estimates. One of the major challenges in…

Quantitative Methods · Quantitative Biology 2018-08-09 Patricio Maturana , Brendon J. Brewer , Steffen Klaere , Remco Bouckaert

We consider networks of dynamical units that evolve in time according to different laws, and are coupled to each other in highly irregular ways. Studying how to steer the dynamics of such systems towards a desired evolution is of great…

Physics and Society · Physics 2020-12-01 Ricardo Gutiérrez , Massimo Materassi , Stefano Focardi , Stefano Boccaletti

This paper introduces a novel multi-stage decision-making model that integrates hypothesis testing and dynamic programming algorithms to address complex decision-making scenarios.Initially,we develop a sampling inspection scheme that…

Systems and Control · Electrical Eng. & Systems 2025-03-11 Ziyang Liu , Yurui Hu , Yihan Deng

Dynamical systems see widespread use in natural sciences like physics, biology, chemistry, as well as engineering disciplines such as circuit analysis, computational fluid dynamics, and control. For simple systems, the differential…

As AI foundation models grow in capability, a deeper question emerges: What shapes their internal cognitive identity -- beyond fluency and output? Benchmarks measure behavior, but the soul of a model resides in its latent geometry. In this…

Artificial Intelligence · Computer Science 2025-10-03 Amitava Das

RNA structure and functional dynamics play fundamental roles in controlling biological systems. Molecular dynamics simulation, which can characterize interactions at an atomistic level, can advance the understanding on new drug discovery,…

Molecular Networks · Quantitative Biology 2023-06-21 Hua Zheng , Wei Xie , Paul Whitford , Ailun Wang , Chunsheng Fang , Wandi Xu

Time-varying mixture densities occur in many scenarios, for example, the distributions of keywords that appear in publications may evolve from year to year, video frame features associated with multiple targets may evolve in a sequence. Any…

Machine Learning · Statistics 2016-04-19 Cheng Luo , Yang Xiang , Richard Yi Da Xu

This paper uses a recent explanation for the fundamental haploid-diploid lifecycle of eukaryotic organisms to present a new memetic algorithm that differs from all previous known work using diploid representations. A form of the Baldwin…

Neural and Evolutionary Computing · Computer Science 2019-11-19 Michail-Antisthenis Tsompanas , Larry Bull , Andrew Adamatzky , Igor Balaz

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

The dominating NLP paradigm of training a strong neural predictor to perform one task on a specific dataset has led to state-of-the-art performance in a variety of applications (eg. sentiment classification, span-prediction based question…

Computation and Language · Computer Science 2021-09-06 Paul Michel

Hybrid modeling provides an effective solution to cope with multiple time scales dynamics in systems biology. Among the applications of this method, one of the most important is the cell cycle regulation. The machinery of the cell cycle,…

Computational Engineering, Finance, and Science · Computer Science 2013-09-05 Vincent Noël , Sergey Vakulenko , Ovidiu Radulescu

The dynamics of protection processes has been a fundamental challenge in systemic risk analysis. The conceptual principle and methodological techniques behind the mechanisms involved [in such dynamics] have been harder to grasp than…

Social and Information Networks · Computer Science 2019-07-29 Chulwook Park

The Harland document management system implements a data model in which document (object) structure can be altered by mixin-style multiple inheritance at any time. This kind of structural fluidity has long been supported by knowledge-base…

Databases · Computer Science 2007-05-23 Paul M. Aoki , Ian E. Smith , James D. Thornton

Neural network potentials (NNPs) offer a powerful alternative to traditional force fields for molecular dynamics (MD) simulations. Accurate and stable MD simulations, crucial for evaluating material properties, require training data…

Machine Learning · Computer Science 2025-06-23 Naoki Matsumura , Yuta Yoshimoto , Yuto Iwasaki , Meguru Yamazaki , Yasufumi Sakai

Single-cell sequencing is revolutionizing biology by enabling detailed investigations of cell-state transitions. Many biological processes unfold along continuous trajectories, yet it remains challenging to extract smooth, low-dimensional…

Machine Learning · Statistics 2025-06-30 Rong Ma , Xi Li , Jingyuan Hu , Bin Yu

The dynamics of systems biological processes are usually modeled by a system of ordinary differential equations (ODEs) with many unknown parameters that need to be inferred from noisy and sparse measurements. Here, we introduce…

Quantitative Methods · Quantitative Biology 2022-02-04 Mitchell Daneker , Zhen Zhang , George Em Karniadakis , Lu Lu