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Related papers: Volumic deformation of human cornea under pressure

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We introduce a new model of the human corneal stroma, regarded as a fluid-saturated continuum, able to describe surface flattening and thickness thinning observed in several pathological conditions. In contrast with more common approaches…

Tissues and Organs · Quantitative Biology 2026-01-05 A. Giammarini , A. Pandolfi

Understanding corneal stiffness is valuable for improving refractive surgery, detecting corneal abnormalities, and assessing intraocular pressure. However, accurately measuring the elastic properties, particularly the tensile and shear…

Medical Physics · Physics 2023-08-11 Guo-Yang Li , Xu Feng , Seok-Hyun Yun

Objective: The mechanical properties of corneal tissues play a crucial role in determining corneal shape and have significant implications in vision care. This study aimed to address the challenge of obtaining accurate in vivo data for the…

Medical Physics · Physics 2023-07-11 Guo-Yang Li , Xu Feng , Seok-Hyun Yun

Keratoconus is a pathology of the cornea associated with a tissue thinning and a weakening of its mechanical properties. However, it remains elusive which aspect is the leading cause of the disease. To investigate this question, we combined…

Medical Physics · Physics 2021-11-25 Chloé Giraudet , Jérome Diaz , Patrick Le Tallec , Jean-Marc Allain

The cornea provides the largest refractive power for the human visual system. Its stiffness, along with intraocular pressure (IOP), are linked to several pathologies, including keratoconus and glaucoma. Although mechanical tests can…

High-resolution optical imaging methods, such as confocal microscopy and full-field optical coherence tomography, capture flat optical sections of the sample. If the sample is curved, the optical field sections through several sample layers…

Medical Physics · Physics 2020-07-31 Viacheslav Mazlin , Kristina Irsch , Michel Paques , Mathias Fink , Albert Claude Boccara

Tear film rupture on the corneal surface plays a critical role in ocular health and visual comfort. Conventional theoretical approaches often idealize the cornea as a perfectly smooth surface, ignoring the surface roughness that are…

Fluid Dynamics · Physics 2026-03-20 Deepak Kumar , S Pushpavanam

Over 140 million people worldwide and over 45 million people in the United States wear contact lenses; it is estimated that 12%-27.4% contact lens users stop wearing them due to discomfort. Contact lens mechanical interactions with the…

Numerical Analysis · Mathematics 2025-12-11 Lucia Carichino , Kara L. Maki , David S. Ross , Riley K. Supple , Evan Rysdam

A stable shape for corneas experiencing refractive surgery has to be sustained so as to elude post-refractive surgery de-compensation. This de-compensation leads to visual complications and unsatisfactory procedure recovery. Variation in…

Medical Physics · Physics 2022-08-30 Hassan M. Ahmed , Nancy M. Salem , Walid I. Al-Atabany

In lens cataract, the clouding change in lens leads to a decline of transparency of part of the lens. There are three types of senile cataract: cortical cataract, nuclear cataract, and posterior/anterior sub-capsular cataract. The most…

Tissues and Organs · Quantitative Biology 2018-02-06 Jicun Wang-Michelitsch , Thomas M. Michelitsch

Optical sections of the cornea are obtained by illumination with a collimated beam expanded in a fan shape by a small rotary cylindrical lens. The light diffused from the cornea is observed by two cameras and processed in order to yield the…

Medical Physics · Physics 2007-05-23 Jose B. Almeida , Sandra Franco

We predict that illumination by a plane electromagnetic wave of optically resonant membranes, such as graphene or monolayers of transition metal dichalcogenides, directly affects their mechanical tension. The induced optomechanical tension…

Mesoscale and Nanoscale Physics · Physics 2019-07-04 I. D. Avdeev , A. N. Poddubny , A. V. Poshakinskiy

The shape of a liquid-air interface advancing on a heterogeneous surface was studied experimentally, together with the force induced by the pinning of the contact line to surface defects. Different surfaces were considered with circular…

Materials Science · Physics 2022-03-22 Solomon S. Melides , Dominic Vella , Marco Ramaioli

To establish the tissue regions necessary to accurately represent the mechanics of the optic nerve head (ONH), imaging data of the ONH from 2 healthy subjects were used to create in vivo subject-specific eye mechanical models considering…

Medical Physics · Physics 2025-05-01 Soumaya Ouhsousou , Lucy Q. Shen , Chhavi Saini , Amin Pourasghar , Mengyu Wang , John C. Brigham

Purpose: Recently the authors presented a technique that allows corneal thickness measurements along any meridian from optical sections obtained using a rotary scanning system. This paper presents 3-D mapping of the corneal thickness and…

General Physics · Physics 2007-05-23 S. Franco , J. B. Almeida , M. Parafita

We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…

Biological Physics · Physics 2023-06-28 Maria Laura De Bellis , Marcello Vasta , Alessio Gizzi , Anna Pandolfi

Objective: To compare non-contact acoustic micro-tapping optical coherence elastography (AuT-OCE) with destructive mechanical tests to confirm corneal elastic anisotropy. Design: Ex vivo, laboratory study with non-contact AuT-OCE followed…

Lens tension is essential for accommodative vision but remains difficult to measure with precision. Here, we present an optical coherence elastography (OCE) technique that quantifies both tension and elastic modulus in the lens capsule and…

Applied Physics · Physics 2025-12-29 Xu Feng , Guo-yang Li , Yuxuan Jiang , Owen Shortt-Nguyen , Seok-Hyun Yun

Dense suspensions of soft colloidal particles display a broad range of physical and rheological properties which are still far from being fully understood. To elucidate the role of deformability on colloidal flow, we employ computer…

Soft Condensed Matter · Physics 2018-08-31 M. Foglino , A. N. Morozov , D. Marenduzzo

Corneal collagen crosslinking (CXL) is commonly used to prevent or treat keratoconus. Although changes in corneal stiffness induced by CXL surgery can be monitored with non-contact dynamic optical coherence elastography (OCE) by tracking…

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