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Currently, deep learning (DL) has achieved the automatic prediction of dose distribution in radiotherapy planning, enhancing its efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Zhenghao Feng , Lu Wen , Peng Wang , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

Although current semi-supervised medical segmentation methods can achieve decent performance, they are still affected by the uncertainty in unlabeled data and model predictions, and there is currently a lack of effective strategies that can…

Computer Vision and Pattern Recognition · Computer Science 2024-04-10 Yuanpeng He

Decision Focused Learning has emerged as a critical paradigm for integrating machine learning with downstream optimisation. Despite its promise, existing methodologies predominantly rely on probabilistic models and focus narrowly on task…

Machine Learning · Computer Science 2025-03-21 Keivan Shariatmadar , Neil Yorke-Smith , Ahmad Osman , Fabio Cuzzolin , Hans Hallez , David Moens

Machine learning has achieved remarkable successes, yet its deployment in safety-critical domains remains hindered by an inherent inability to manage uncertainty, resulting in overconfident and unreliable predictions when models encounter…

Machine Learning · Computer Science 2025-10-28 Shireen Kudukkil Manchingal

Epistemic uncertainty is crucial for safety-critical applications and data acquisition tasks. Yet, we find an important phenomenon in deep learning models: an epistemic uncertainty collapse as model complexity increases, challenging the…

Machine Learning · Computer Science 2025-05-27 Andreas Kirsch

Data-driven control in unknown environments requires a clear understanding of the involved uncertainties for ensuring safety and efficient exploration. While aleatoric uncertainty that arises from measurement noise can often be explicitly…

Machine Learning · Computer Science 2023-07-13 Neha Das , Jonas Umlauft , Armin Lederer , Thomas Beckers , Sandra Hirche

We consider the problem of uncertainty estimation in the context of (non-Bayesian) deep neural classification. In this context, all known methods are based on extracting uncertainty signals from a trained network optimized to solve the…

Machine Learning · Computer Science 2019-04-25 Yonatan Geifman , Guy Uziel , Ran El-Yaniv

Deep neural networks are powerful tools to detect hidden patterns in data and leverage them to make predictions, but they are not designed to understand uncertainty and estimate reliable probabilities. In particular, they tend to be…

Machine Learning · Statistics 2022-11-10 Bat-Sheva Einbinder , Yaniv Romano , Matteo Sesia , Yanfei Zhou

Accurate uncertainty quantification remains a key challenge for standard LLMs, prompting the adoption of Bayesian and ensemble-based methods. However, such methods typically necessitate computationally expensive sampling, involving multiple…

Machine Learning · Computer Science 2025-07-25 Lakshmana Sri Harsha Nemani , P. K. Srijith , Tomasz Kuśmierczyk

Automated mental health prediction using textual data has shown promising results with deep learning and large language models. However, deploying these models in high-stakes real-world settings remains challenging, as existing approaches…

Computation and Language · Computer Science 2026-05-07 Yucheng Ruan , Ling Huang , Qika Lin , Kai He , Mengling Feng

In this paper, we propose TEDL, a two-stage learning approach to quantify uncertainty for deep learning models in classification tasks, inspired by our findings in experimenting with Evidential Deep Learning (EDL) method, a recently…

Machine Learning · Computer Science 2022-09-14 Xue Li , Wei Shen , Denis Charles

Modeling the absorbed dose during X-ray imaging is essential for optimizing radiation exposure. Monte Carlo simulations (MCS) are the gold standard for precise 3D dose estimation but require significant computation time. Deep learning…

Medical Physics · Physics 2025-02-14 Maxime Rousselot , Jing Zhang , Didier Benoit , Chi-Hieu Pham , Julien Bert

Data-driven methods based on machine learning have the potential to accelerate computational analysis of atomic structures. In this context, reliable uncertainty estimates are important for assessing confidence in predictions and enabling…

Machine Learning · Computer Science 2021-11-04 Jonas Busk , Peter Bjørn Jørgensen , Arghya Bhowmik , Mikkel N. Schmidt , Ole Winther , Tejs Vegge

In supervised learning, understanding an input's proximity to the training data can help a model decide whether it has sufficient evidence for reaching a reliable prediction. While powerful probabilistic models such as Gaussian Processes…

Machine Learning · Computer Science 2024-06-19 Ifigeneia Apostolopoulou , Benjamin Eysenbach , Frank Nielsen , Artur Dubrawski

Quantifying prediction uncertainty when applying object detection models to new, unlabeled datasets is critical in applied machine learning. This study introduces an approach to estimate the performance of deep learning-based object…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Ni Li , Ryan Jacobs , Matthew Lynch , Vidit Agrawal , Kevin Field , Dane Morgan

Uncertainty-quantification methods are applied to estimate the confidence of deep-neural-networks classifiers over their predictions. However, most widely used methods are known to be overconfident. We address this problem by developing an…

Machine Learning · Computer Science 2023-05-19 Luigi Sbailò , Luca M. Ghiringhelli

Understanding the uncertainty inherent in deep learning-based image registration models has been an ongoing area of research. Existing methods have been developed to quantify both transformation and appearance uncertainties related to the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-11 Junyu Chen , Yihao Liu , Shuwen Wei , Zhangxing Bian , Aaron Carass , Yong Du

Uncertainty quantification is central to safe and efficient deployments of deep learning models, yet many computationally practical methods lack lacking rigorous theoretical motivation. Random network distillation (RND) is a lightweight…

Machine Learning · Computer Science 2026-02-27 Moritz A. Zanger , Yijun Wu , Pascal R. Van der Vaart , Wendelin Böhmer , Matthijs T. J. Spaan

Uncertainty estimation in deep learning has become a leading research field in medical image analysis due to the need for safe utilisation of AI algorithms in clinical practice. Most approaches for uncertainty estimation require sampling…

Image and Video Processing · Electrical Eng. & Systems 2022-04-12 Kaisar Kushibar , Víctor Manuel Campello , Lidia Garrucho Moras , Akis Linardos , Petia Radeva , Karim Lekadir

Quantifying uncertainty in a model's predictions is important as it enables the safety of an AI system to be increased by acting on the model's output in an informed manner. This is crucial for applications where the cost of an error is…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Aria Khoshsirat
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