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Automated volumetric segmentation of the pancreas on cross-sectional imaging is needed for diagnosis and follow-up of pancreatic diseases. While CT-based pancreatic segmentation is more established, MRI-based segmentation methods are…

Background: Pancreatic cancer is one of the most aggressive cancers, with poor survival rates. Endoscopic ultrasound (EUS) is a key diagnostic modality, but its effectiveness is constrained by operator subjectivity. This study evaluates a…

Pancreatic cancer is one of the global leading causes of cancer-related deaths. Despite the success of Deep Learning in computer-aided diagnosis and detection (CAD) methods, little attention has been paid to the detection of Pancreatic…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Christiaan G. A. Viviers , Mark Ramaekers , Peter H. N. de With , Dimitrios Mavroeidis , Joost Nederend , Misha Luyer , Fons van der Sommen

Intraductal Papillary Mucinous Neoplasm (IPMN) cysts are pre-malignant pancreas lesions, and they can progress into pancreatic cancer. Therefore, detecting and stratifying their risk level is of ultimate importance for effective treatment…

Molecular subtyping of PDAC into basal-like and classical has established prognostic and predictive value. However, its use in clinical practice is limited by cost, turnaround time, and tissue requirements, thereby restricting its…

Early detection improves prognosis in pancreatic ductal adenocarcinoma (PDAC) but is challenging as lesions are often small and poorly defined on contrast-enhanced computed tomography scans (CE-CT). Deep learning can facilitate PDAC…

Image and Video Processing · Electrical Eng. & Systems 2022-01-14 Natália Alves , Megan Schuurmans , Geke Litjens , Joeran S. Bosma , John Hermans , Henkjan Huisman

This work presents comprehensive results to detect in the early stage the pancreatic neuroendocrine tumors (PNETs), a group of endocrine tumors arising in the pancreas, which are the second common type of pancreatic cancer, by checking the…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Zhuotun Zhu , Yongyi Lu , Wei Shen , Elliot K. Fishman , Alan L. Yuille

The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of which may develop into PDAC. Previous computer-aided…

Computer Vision and Pattern Recognition · Computer Science 2018-06-20 Hongwei Li , Kanru Lin , Maximilian Reichert , Lina Xu , Rickmer Braren , Deliang Fu , Roland Schmid , Ji Li , Bjoern Menze , Kuangyu Shi

Pancreatic cancer with more than 60,000 new cases each year has less than 10 percent 5-year overall survival. Radiation therapy (RT) is an effective treatment for Locally advanced pancreatic cancer (LAPC). The current clinical RT workflow…

Medical Physics · Physics 2023-06-07 Hamed Hooshangnejad , Quan Chen , Xue Feng , Rui Zhang , Kai Ding

Objective: Our study aimed to evaluate and validate PanSegNet, a deep learning (DL) algorithm for pediatric pancreas segmentation on MRI in children with acute pancreatitis (AP), chronic pancreatitis (CP), and healthy controls. Methods:…

Despite the advances in medicine, cancer has remained a formidable challenge. Particularly in the case of pancreatic tumors, characterized by their diversity and late diagnosis, early detection poses a significant challenge crucial for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-06 Reza Babaei , Samuel Cheng , Theresa Thai , Shangqing Zhao

Pancreas segmentation has been traditionally challenging due to its small size in computed tomography abdominal volumes, high variability of shape and positions among patients, and blurred boundaries due to low contrast between the pancreas…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Andrea Moglia , Matteo Cavicchioli , Luca Mainardi , Pietro Cerveri

Pancreatic NEuroendocrine Tumors (pNETs) are very rare endocrine neoplasms that account for less than 5% of all pancreatic malignancies, with an incidence of only 1-1.5 cases per 100,000. Early detection of pNETs is critical for improving…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Wenqi Li , Yingli Chen , Keyang Zhou , Xiaoxiao Hu , Zilu Zheng , Yue Yan , Xinpeng Zhang , Wei Tang , Zhenxing Qian

Objectives: Pancreatic cancer is a lethal disease, hard to diagnose and usually results in poor prognosis and high mortality. Developing an artificial intelligence (AI) algorithm to accurately and universally predict the early cancer risk…

The presence of tertiary lymphoid structures (TLSs) on pancreatic pathological images is an important prognostic indicator of pancreatic tumors. Therefore, TLSs detection on pancreatic pathological images plays a crucial role in diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2023-07-28 Bingxue Wang , Liwen Zou , Jun Chen , Yingying Cao , Zhenghua Cai , Yudong Qiu , Liang Mao , Zhongqiu Wang , Jingya Chen , Luying Gui , Xiaoping Yang

Acute pancreatitis (AP) is a common and potentially life-threatening gastrointestinal disease that imposes a significant burden on healthcare systems. ICU readmissions among AP patients are common, especially in severe cases, with rates…

Applications · Statistics 2025-05-22 Shuheng Chen , Yong Si , Junyi Fan , Li Sun , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Automatic segmentation of an organ and its cystic region is a prerequisite of computer-aided diagnosis. In this paper, we focus on pancreatic cyst segmentation in abdominal CT scan. This task is important and very useful in clinical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-23 Yuyin Zhou , Lingxi Xie , Elliot K. Fishman , Alan L. Yuille

Pancreatic cancer carries a poor prognosis and relies on endoscopic ultrasound (EUS) for targeted biopsy and radiotherapy. However, the speckle noise, low contrast, and unintuitive appearance of EUS make segmentation of pancreatic tumors…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Pascal Spiegler , Taha Koleilat , Arash Harirpoush , Corey S. Miller , Hassan Rivaz , Marta Kersten-Oertel , Yiming Xiao

Pancreatic cancer, which has a low survival rate, is one of the most challenging cancers to diagnose and treat effectively. Early detection through abdominal computed tomography (CT) scans is crucial, yet complicated by the pancreas'…

Image and Video Processing · Electrical Eng. & Systems 2025-07-18 Xubei Zhang , Mikhail Y. Shalaginov , Tingying Helen Zeng
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