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Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

Finding a Hadamard matrix of a specific order using a quantum computer can lead to a demonstration of practical quantum advantage. Earlier efforts using a quantum annealer were impeded by the limitations of the present quantum resource and…

Quantum Physics · Physics 2024-10-15 Andriyan Bayu Suksmono

In this paper, the Quantum Approximate Optimization Algorithm (QAOA) is analyzed by leveraging symmetries inherent in problem Hamiltonians. We focus on the generalized formulation of optimization problems defined on the sets of $n$-element…

Quantum Physics · Physics 2024-01-23 Boris Tsvelikhovskiy , Ilya Safro , Yuri Alexeev

In the pursuit of achieving near-term quantum advantage for combinatorial optimization problems, the Quantum Approximate Optimization Algorithm (QAOA) and the Variational Quantum Eigensolver (VQE) are the primary methods of interest, but…

Quantum Physics · Physics 2025-03-06 Adelina Bärligea , Benedikt Poggel , Jeanette Miriam Lorenz

Search-based software engineering (SBSE) addresses critical optimization challenges in software engineering, including the next release problem (NRP) and feature selection problem (FSP). While traditional heuristic approaches and integer…

Software Engineering · Computer Science 2025-07-01 Shuchang Wang , Xiaopeng Qiu , Yingxing Xue , Yanfu Li , Wei Yang

Combinatorial optimization is a challenging problem applicable in a wide range of fields from logistics to finance. Recently, quantum computing has been used to attempt to solve these problems using a range of algorithms, including…

Quantum Physics · Physics 2024-03-06 Jonathan Wurtz , Stefan Sack , Sheng-Tao Wang

We establish and discuss a number of connections between a digitized version of Quantum Annealing (QA) with the Quantum Approximate Optimization Algorithm (QAOA) introduced by Farhi et al. (arXiv:1411.4028) as an alternative hybrid…

Quantum Physics · Physics 2019-12-10 Glen Bigan Mbeng , Rosario Fazio , Giuseppe Santoro

The Quantum Approximate Optimization Algorithm (QAOA) is a quantum-classical hybrid algorithm intending to find the ground state of a target Hamiltonian. Theoretically, QAOA can obtain the approximate solution if the quantum circuit is deep…

Quantum Physics · Physics 2022-04-26 Yahui Chai , Yong-Jian Han , Yu-Chun Wu , Ye Li , Menghan Dou , Guo-Ping Guo

We present a quantum algorithm for portfolio optimisation. Specifically, We present an end-to-end quantum approximate optimisation algorithm (QAOA) to solve the discrete global minimum variance portfolio (DGMVP) model. This model finds a…

Quantum Physics · Physics 2024-10-22 Haomu Yuan , Christopher K. Long , Hugo V. Lepage , Crispin H. W. Barnes

Many quantum algorithms seek to output a specific bitstring solving the problem of interest--or a few if the solution is degenerate. It is the case for the quantum approximate optimization algorithm (QAOA) in the limit of large circuit…

Quantum Physics · Physics 2022-08-23 Maxime Dupont , Nicolas Didier , Mark J. Hodson , Joel E. Moore , Matthew J. Reagor

The quantum approximate optimization algorithm (QAOA) is a promising quantum algorithm that can be used to approximately solve combinatorial optimization problems. The usual QAOA ansatz consists of an alternating application of the cost and…

Quantum Physics · Physics 2024-11-01 Anthony Wilkie , Igor Gaidai , James Ostrowski , Rebekah Herrman

We introduce a variational algorithm based on the quantum alternating operator ansatz (QAOA) for the approximate solution of computationally hard counting problems. Our algorithm, dubbed VQCount, is based on the equivalence between random…

Quantum Physics · Physics 2026-04-16 Julien Drapeau , Shreya Banerjee , Stefanos Kourtis

Currency arbitrage capitalizes on price discrepancies in currency exchange rates between markets to produce profits with minimal risk. By employing a combinatorial optimization problem, one can ascertain optimal paths within directed…

Computational Finance · Quantitative Finance 2025-02-25 Sangram Deshpande , Elin Ranjan Das , Frank Mueller

Designing noisy-resilience quantum algorithms is indispensable for practical applications on Noisy Intermediate-Scale Quantum~(NISQ) devices. Here we propose a quantum approximate optimization algorithm~(QAOA) with a very shallow circuit,…

Quantum Physics · Physics 2021-09-27 Fang-Gang Duan , Dan-Bo Zhang

We implement two Quantum Approximate Optimisation Algorithm (QAOA) variants for a battery revenue optimisation problem, equivalent to the weakly NP-hard Knapsack Problem. Both approaches investigate how to tackle constrained problems with…

Emerging Technologies · Computer Science 2019-08-16 Pierre Dupuy de la Grand'rive , Jean-Francois Hullo

To arrive at some viable product design, product development processes frequently use numerical simulations and mathematical programming techniques. Topology optimization, in particular, is one of the most promising techniques for…

Quantum Physics · Physics 2025-05-06 Yuki Sato , Ruho Kondo , Satoshi Koide , Seiji Kajita

The Quantum Approximate Optimization Algorithm (QAOA) has enjoyed increasing attention in noisy intermediate-scale quantum computing due to its application to combinatorial optimization problems. Because combinatorial optimization problems…

Optimization and Control · Mathematics 2024-01-18 Yunsoo Ha , Sara Shashaani , Matt Menickelly

The quantum approximate optimization algorithm (QAOA) generates an approximate solution to combinatorial optimization problems using a variational ansatz circuit defined by parameterized layers of quantum evolution. In theory, the…

Quantum Physics · Physics 2021-09-24 Rebekah Herrman , Phillip C. Lotshaw , James Ostrowski , Travis S. Humble , George Siopsis

The quantum approximate optimization algorithm (QAOA) is considered to be one of the most promising approaches towards using near-term quantum computers for practical application. In its original form, the algorithm applies two different…

Quantum Physics · Physics 2021-04-08 Mauro E. S. Morales , Jacob Biamonte , Zoltán Zimborás

Real-world optimization problems must undergo a series of transformations before becoming solvable on current quantum hardware. Even for a fixed problem, the number of possible transformation paths -- from industry-relevant formulations…

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