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The clinical time-series setting poses a unique combination of challenges to data modeling and sharing. Due to the high dimensionality of clinical time series, adequate de-identification to preserve privacy while retaining data utility is…

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Synthetic data has gained significant momentum thanks to sophisticated machine learning tools that enable the synthesis of high-dimensional datasets. However, many generation techniques do not give the data controller control over what…

Cryptography and Security · Computer Science 2022-11-22 Florimond Houssiau , Samuel N. Cohen , Lukasz Szpruch , Owen Daniel , Michaela G. Lawrence , Robin Mitra , Henry Wilde , Callum Mole

The availability of genomic data is essential to progress in biomedical research, personalized medicine, etc. However, its extreme sensitivity makes it problematic, if not outright impossible, to publish or share it. As a result, several…

Genomics · Quantitative Biology 2022-01-19 Bristena Oprisanu , Georgi Ganev , Emiliano De Cristofaro

The integration of privacy measures, including differential privacy techniques, ensures a provable privacy guarantee for the synthetic data. However, challenges arise for Generative Deep Learning models when tasked with generating realistic…

Machine Learning · Computer Science 2024-09-27 Anantaa Kotal , Anupam Joshi

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

Synthetic data generation, a cornerstone of Generative Artificial Intelligence, promotes a paradigm shift in data science by addressing data scarcity and privacy while enabling unprecedented performance. As synthetic data becomes more…

Machine Learning · Statistics 2024-03-12 Xiaotong Shen , Yifei Liu , Rex Shen

Advances in generative models have transformed the field of synthetic image generation for privacy-preserving data synthesis (PPDS). However, the field lacks a comprehensive survey and comparison of synthetic image generation methods across…

Cryptography and Security · Computer Science 2025-06-27 Yunsung Chung , Yunbei Zhang , Nassir Marrouche , Jihun Hamm

Access to genomic data is highly regulated due to its sensitive nature. While safeguards are essential, cumbersome data access processes pose a significant barrier to the development of AI methods for genomics. Synthetic data generation can…

Cryptography and Security · Computer Science 2026-05-01 Daniil Filienko , Martine De Cock , Sikha Pentyala

Recent advancements in generative AI have made it possible to create synthetic datasets that can be as accurate as real-world data for training AI models, powering statistical insights, and fostering collaboration with sensitive datasets…

Machine Learning · Computer Science 2025-01-08 Amy Steier , Lipika Ramaswamy , Andre Manoel , Alexa Haushalter

Smartwatch health sensor data are increasingly utilized in smart health applications and patient monitoring, including stress detection. However, such medical data often comprise sensitive personal information and are resource-intensive to…

Machine Learning · Computer Science 2026-02-03 Lucas Lange , Nils Wenzlitschke , Erhard Rahm

The digitization of medical records ushered in a new era of big data to clinical science, and with it the possibility that data could be shared, to multiply insights beyond what investigators could abstract from paper records. The need to…

Machine Learning · Computer Science 2021-06-03 Ofer Mendelevitch , Michael D. Lesh

Since technology is advancing so quickly in the modern era of information, data is becoming an essential resource in many fields. Correct data collection, organization, and analysis make it a potent tool for successful decision-making,…

Machine Learning · Computer Science 2024-05-28 Dilsat Berin Aytar , Semra Gunduc

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Creation of a synthetic dataset that faithfully represents the data distribution and simultaneously preserves privacy is a major research challenge. Many space partitioning based approaches have emerged in recent years for answering…

Cryptography and Security · Computer Science 2023-06-26 Eleonora Kreačić , Navid Nouri , Vamsi K. Potluru , Tucker Balch , Manuela Veloso

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alternative. Recent successes with numerical and tabular data…

Computation and Language · Computer Science 2025-03-05 Atiquer Rahman Sarkar , Yao-Shun Chuang , Noman Mohammed , Xiaoqian Jiang

Machine learning heavily relies on data, but real-world applications often encounter various data-related issues. These include data of poor quality, insufficient data points leading to under-fitting of machine learning models, and…

Machine Learning · Computer Science 2025-04-07 Yingzhou Lu , Lulu Chen , Yuanyuan Zhang , Minjie Shen , Huazheng Wang , Xiao Wang , Capucine van Rechem , Tianfan Fu , Wenqi Wei

The protection of private information is of vital importance in data-driven research, business, and government. The conflict between privacy and utility has triggered intensive research in the computer science and statistics communities,…

Cryptography and Security · Computer Science 2022-08-11 March Boedihardjo , Thomas Strohmer , Roman Vershynin

Artificial intelligence (AI) has the potential to transform healthcare, but it requires access to health data. Synthetic data that is generated through machine learning models trained on real data, offers a way to share data while…

Computers and Society · Computer Science 2025-08-13 Vibeke Binz Vallevik , Anne Kjersti C. Befring , Severin Elvatun , Jan Franz Nygaard

Background: Heart failure (HF) research is constrained by limited access to large, shareable datasets due to privacy regulations and institutional barriers. Synthetic data generation offers a promising solution to overcome these challenges…

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