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The human brain is a complex network that supports mental function. The nascent field of network neuroscience applies tools from mathematics to neuroimaging data in the hopes of shedding light on cognitive function. A critical question…

Neurons and Cognition · Quantitative Biology 2017-04-26 John D. Medaglia , Perry Zurn , Walter Sinnott-Armstrong , Danielle S. Bassett

Much of neuroscience aims at reverse engineering the brain, but we only record a small number of neurons at a time. We do not currently know if reverse engineering the brain requires us to simultaneously record most neurons or if multiple…

Neurons and Cognition · Quantitative Biology 2019-07-04 Elahe Arani , Sofia Triantafillou , Konrad P. Kording

In this study, we propose a neural network approach to capture the functional connectivities among anatomic brain regions. The suggested approach estimates a set of brain networks, each of which represents the connectivity patterns of a…

Computer Vision and Pattern Recognition · Computer Science 2018-07-24 Baran Baris Kivilcim , Itir Onal Ertugrul , Fatos T. Yarman Vural

With the recent success of deep neural networks in computer vision, it is important to understand the internal working of these networks. What does a given neuron represent? The concepts captured by a neuron may be hard to understand or…

Computer Vision and Pattern Recognition · Computer Science 2020-12-29 Suryabhan Singh Hada , Miguel Á. Carreira-Perpiñán

In neuroscience, researchers have developed informal notions of what it means to reverse engineer a system, e.g., being able to model or simulate a system in some sense. A recent influential paper of Jonas and Kording, that examines a…

Information Theory · Computer Science 2021-10-05 Keerthana Gurushankar , Pulkit Grover

Cognition is supported by neurophysiological processes that occur both in local anatomical neighborhoods and in distributed large-scale circuits. Recent evidence from network control theory suggests that white matter pathways linking…

Neurons and Cognition · Quantitative Biology 2016-06-30 John D. Medaglia , Shi Gu , Fabio Pasqualetti , Rebecca L. Ashare , Caryn Lerman , Joseph Kable , Danielle S. Bassett

Cognitive control is a suite of processes that helps individuals pursue goals despite resistance or uncertainty about what to do. Although cognitive control has been extensively studied as a dynamic feedback loop of perception, valuation,…

Controlling a complex network towards a desired state is of great importance in many applications. A network can be controlled by inputting suitable external signals into some selected nodes, which are called driver nodes. Previous works…

Systems and Control · Electrical Eng. & Systems 2022-06-07 Xizhe Zhang , Yuyan Zhu , Yongkang Zhao

The neural networks of the brain are capable of learning statistical input regularities on the basis of synaptic learning, functional integration into increasingly larger, interconnected neural assemblies, and self organization. This self…

Robotics · Computer Science 2022-06-10 Birgitta Dresp-Langley

Cognitive control researchers aim to describe the processes that support adaptive cognition to achieve specific goals. Control theorists consider how to influence the state of systems to reach certain user-defined goals. In brain networks,…

Neurons and Cognition · Quantitative Biology 2018-06-04 John D. Medaglia

Traditional approaches to understanding the brain's resilience to neuropathology have identified neurophysiological variables, often described as brain or cognitive 'reserve,' associated with better outcomes. However, mechanisms of function…

Neurons and Cognition · Quantitative Biology 2017-01-18 John D. Medaglia , Fabio Pasqualetti , Roy H. Hamilton , Sharon L. Thompson-Schill , Danielle S. Bassett

Recurrent Neural Networks (RNNs) are popular models of brain function. The typical training strategy is to adjust their input-output behavior so that it matches that of the biological circuit of interest. Even though this strategy ensures…

Neurons and Cognition · Quantitative Biology 2020-11-09 Alessandro Salatiello , Martin A. Giese

Recurrent neural networks (RNNs) are a widely used tool for modeling sequential data, yet they are often treated as inscrutable black boxes. Given a trained recurrent network, we would like to reverse engineer it--to obtain a quantitative,…

Machine Learning · Computer Science 2019-12-06 Niru Maheswaranathan , Alex Williams , Matthew D. Golub , Surya Ganguli , David Sussillo

Recurrent Neural Networks (RNNs) are frequently used to model aspects of brain function and structure. In this work, we trained small fully-connected RNNs to perform temporal and flow control tasks with time-varying stimuli. Our results…

Neurons and Cognition · Quantitative Biology 2023-06-29 Cecilia Jarne , Rodrigo Laje

This paper introduces a framework for quantitative characterization of the controllability of time-varying linear systems (or networks) in terms of input novelty. The motivation for such an approach comes from the study of biophysical…

Optimization and Control · Mathematics 2014-11-24 Gautam Kumar , Delsin Menolascino , ShiNung Ching

Neuron reconstruction is essential to generate exquisite neuron connectivity map for understanding brain function. Despite the significant amount of effect that has been made on automatic reconstruction methods, manual tracing by…

Computer Vision and Pattern Recognition · Computer Science 2020-03-20 Donghuan Lu , Sujun Zhao , Peng Xie , Kai Ma , Lijuan Liu , Yefeng Zheng

In several papers published in Biological Cybernetics in the 1980s and 1990s, Kawato and colleagues proposed computational models explaining how internal models are acquired in the cerebellum. These models were later supported by…

Neurons and Cognition · Quantitative Biology 2021-12-22 Mitsuo Kawato , Aurelio Cortese

Various research initiatives try to utilize the operational principles of organisms and brains to develop alternative, biologically inspired computing paradigms and artificial cognitive systems. This paper reviews key features of the…

Adaptation and Self-Organizing Systems · Physics 2012-01-25 Andreas Schierwagen

The brain processes information through many layers of neurons. This deep architecture is representationally powerful, but it complicates learning by making it hard to identify the responsible neurons when a mistake is made. In machine…

Neurons and Cognition · Quantitative Biology 2014-11-04 Timothy P. Lillicrap , Daniel Cownden , Douglas B. Tweed , Colin J. Akerman

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

Quantitative Methods · Quantitative Biology 2020-03-20 Shikuang Deng , Shi Gu
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