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The field of explainability in artificial intelligence (AI) has witnessed a growing number of studies and increasing scholarly interest. However, the lack of human-friendly and individual interpretations in explaining the outcomes of…

Artificial Intelligence · Computer Science 2025-02-04 Toygar Tanyel , Serkan Ayvaz , Bilgin Keserci

Explainable AI (XAI) is an increasingly important area of machine learning research, which aims to make black-box models transparent and interpretable. In this paper, we propose a novel approach to XAI that uses the so-called counterfactual…

Artificial Intelligence · Computer Science 2023-08-02 Bastian Pfeifer , Mateusz Krzyzinski , Hubert Baniecki , Anna Saranti , Andreas Holzinger , Przemyslaw Biecek

In the field of Explainable Artificial Intelligence (XAI), counterfactual examples explain to a user the predictions of a trained decision model by indicating the modifications to be made to the instance so as to change its associated…

Artificial Intelligence · Computer Science 2023-05-11 Thibault Laugel , Adulam Jeyasothy , Marie-Jeanne Lesot , Christophe Marsala , Marcin Detyniecki

Many visualizations have been developed for explainable AI (XAI), but they often require further reasoning by users to interpret. Investigating XAI for high-stakes medical diagnosis, we propose improving domain alignment with diagrammatic…

Artificial Intelligence · Computer Science 2025-02-27 Brian Y. Lim , Joseph P. Cahaly , Chester Y. F. Sng , Adam Chew

Counterfactual explanations have emerged as a prominent method in Explainable Artificial Intelligence (XAI), providing intuitive and actionable insights into Machine Learning model decisions. In contrast to other traditional feature…

In recent years, AI systems in the medical domain have advanced significantly. However, despite outperforming humans, they are rarely used in practice since it is often not clear how they make their decisions. Optimal explanation and…

Human-Computer Interaction · Computer Science 2026-05-06 Julia Wagner , Tim Schlippe

In explainable artificial intelligence (XAI) research, the predominant focus has been on interpreting models for experts and practitioners. Model agnostic and local explanation approaches are deemed interpretable and sufficient in many…

Artificial Intelligence · Computer Science 2024-02-01 Adarsa Sivaprasad , Ehud Reiter , Nava Tintarev , Nir Oren

Explainable artificial intelligence (XAI) plays an indispensable role in demystifying the decision-making processes of AI, especially within the healthcare industry. Clinicians rely heavily on detailed reasoning when making a diagnosis,…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Anna Stubbin , Thompson Chyrikov , Jim Zhao , Christina Chajo

Explainable artificial intelligence (XAI) has helped elucidate the internal mechanisms of machine learning algorithms, bolstering their reliability by demonstrating the basis of their predictions. Several XAI models consider causal…

Machine Learning · Computer Science 2024-04-30 Daisuke Takahashi , Shohei Shimizu , Takuma Tanaka

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Accurate and interpretable image-based diagnosis remains a fundamental challenge in medical AI, particularly under domain shifts and rare-class conditions. Deep learning models often struggle with real-world distribution changes, exhibit…

Machine Learning · Computer Science 2025-12-13 Midhat Urooj , Ayan Banerjee , Farhat Shaikh , Kuntal Thakur , Sandeep Gupta

Counterfactual explanations have emerged as a popular solution for the eXplainable AI (XAI) problem of elucidating the predictions of black-box deep-learning systems due to their psychological validity, flexibility across problem domains…

Machine Learning · Computer Science 2022-12-20 Eoin Delaney , Arjun Pakrashi , Derek Greene , Mark T. Keane

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

Explainable artificial intelligence (XAI) has become increasingly important in biomedical image analysis to promote transparency, trust, and clinical adoption of DL models. While several surveys have reviewed XAI techniques, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Getamesay Haile Dagnaw , Yanming Zhu , Muhammad Hassan Maqsood , Wencheng Yang , Xingshuai Dong , Xuefei Yin , Alan Wee-Chung Liew

With the increasing availability of structured and unstructured data and the swift progress of analytical techniques, Artificial Intelligence (AI) is bringing a revolution to the healthcare industry. With the increasingly indispensable role…

Machine Learning · Computer Science 2020-11-09 Devam Dave , Het Naik , Smiti Singhal , Pankesh Patel

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

We propose a BlackBox Counterfactual Explainer, designed to explain image classification models for medical applications. Classical approaches (e.g., saliency maps) that assess feature importance do not explain "how" imaging features in…

Computer Vision and Pattern Recognition · Computer Science 2022-11-21 Sumedha Singla , Motahhare Eslami , Brian Pollack , Stephen Wallace , Kayhan Batmanghelich

ProfileXAI is a model- and domain-agnostic framework that couples post-hoc explainers (SHAP, LIME, Anchor) with retrieval - augmented LLMs to produce explanations for different types of users. The system indexes a multimodal knowledge base,…

Counterfactual medical image generation have emerged as a critical tool for enhancing AI-driven systems in medical domain by answering "what-if" questions. However, existing approaches face two fundamental limitations: First, they fail to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Hyungi Min , Taeseung You , Hangyeul Lee , Yeongjae Cho , Sungzoon Cho

With the rising necessity of explainable artificial intelligence (XAI), we see an increase in task-dependent XAI methods on varying abstraction levels. XAI techniques on a global level explain model behavior and on a local level explain…

Human-Computer Interaction · Computer Science 2023-07-18 Udo Schlegel , Daniela Oelke , Daniel A. Keim , Mennatallah El-Assady
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